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Mass Spectrometry Market Size, Share & Trends Analysis Report By Product (Instruments, Consumables & Service), By Technology (Quadrupole Liquid Chromatography-Mass Spectrometry, Gas Chromatography- Mass Spectrometry (GC- MS), Fourier Transform-Mass Spectrometry (FT-MS), Time-of-Flight Mass Spectrometry (TOFMS), Matrix Assisted Laser Desorption/Ionization- Time-of-Flight Mass Spectrometry (MALDI- TOF), Magnetic Sector Mass Spectrometry, Others), By Application (Proteomics, Metabolomics, Lipidomics, Glycomics, Others), By End User (Government & Academic Institutions, Pharmaceutical & Biotechnology Companies, Others) and By Region(North America, Europe, APAC, Middle East and Africa, LATAM) Forecasts, 2024-2032

Report Code: SRHI7DR
Last Updated : Jan 16, 2025
Author : Straits Research
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Mass Spectrometry Market Size

The global mass spectrometry market size was valued at USD 6.93 billion in 2024 and is projected to grow from USD 7.33 billion in 2025 to reach USD 12.33 billion by 2033, exhibiting a CAGR of 6.7% during the forecast period (2025 – 2033). 

Mass spectrometry is a powerful analytical technique used to measure the mass-to-charge ratio of ions. It helps identify and quantify molecules in a sample, providing detailed information about their structure and composition. Widely applied across industries, it plays a vital role in healthcare, pharmaceutical research, biotechnology, food safety, and environmental testing.

The technology works by ionizing chemical compounds, separating the ions based on their mass-to-charge ratio, and detecting them to generate data. Its precision and sensitivity make it indispensable for advancing scientific fields like genomics, proteomics, and precision medicine, enabling breakthroughs in diagnostics, drug discovery, and environmental monitoring.

The global market is expanding due to rising applications in healthcare and clinical testing, food and environmental testing, and its extensive use in the pharmaceutical and biotechnology sectors. Technological advancements further drive this growth. For example, in December 2024, Roche launched the cobas mass spec solution, transforming diagnostics with unmatched sensitivity and specificity, offering clinicians deeper insights.

Such innovations are accelerating the shift towards precision medicine by enabling breakthroughs in genomics and proteomics, fostering a personalized approach to healthcare.

Mass Spectrometry Market Trends

Emergence of imaging mass spectrometry

The growing adoption of imaging mass spectrometry is revolutionizing molecular analysis, marking significant advancements in visualizing molecular distribution on surfaces, such as tissue sections. This technology enables researchers to detect and analyze intact proteins, lipids, and other biological molecules, enhancing the precision of biomedical research and diagnostics. Recent developments are pushing boundaries, enabling high-resolution imaging that can reveal intricate molecular landscapes.

For instance, in May 2024, scientists at Vanderbilt University in Nashville, Tennessee, tested advanced imaging mass spectrometry techniques on proteins, showcasing the potential to deepen our understanding of biological processes.

These innovations are fueling the broader application in fields like pathology and pharmaceuticals, propelling the market toward sustained growth and diversification.

Increasing adoption of mass spectrometry in proteomics and metabolomics

Mass spectrometry is transforming proteomics and metabolomics by enabling detailed insights into disease mechanisms and physiological functions. Proteomics benefits from its ability to detect and quantify a wide range of proteins in a sample, while metabolomics uses it to analyze small molecules that play critical roles in cellular processes. These capabilities are vital for disease diagnosis, biomarker discovery, and therapeutic advancements.

  • For instance, in June 2024, Bruker introduced the timsTOF Ultra 2, featuring ultra-high sensitivity for single-cell and sub-cellular proteomics. This innovation opens new research avenues, enabling scientists to delve deeper into the molecular intricacies of diseases.

The integration of mass spectrometry in these fields is driving a paradigm shift, pushing market growth through technological breakthroughs and expanding applications.


Mass Spectrometry Market Growth Factors

Increasing investments in R&D of pharmaceutical industries

Pharmaceutical and biotechnology companies are heavily investing in developing new molecules, leveraging mass spectrometry throughout the drug development lifecycle—from early discovery to clinical trials. This reliance on mass spectrometry underscores its vital role in ensuring precision, accuracy, and efficiency in drug research.

For instance, in November 2024, AstraZeneca announced a $3.5 billion investment in U.S. manufacturing and R&D, aiming to bolster its global expansion through advanced R&D centers worldwide.

Such substantial investments enhance the adoption of mass spectrometry tools, directly contributing to the market's growth. The trend highlights the increasing demand for advanced analytical tools in the pharmaceutical sector.

Increasing new product launches with advanced technologies

The continuous launch of technologically advanced mass spectrometry instruments is propelling market growth by catering to the evolving needs of diverse industries. These innovations enhance the precision, sensitivity, and scope of analytical capabilities, positioning it as a cutting-edge solution for complex analyses.

  • For example, in June 2024, Agilent introduced groundbreaking GC/MS and LC/Q-TOF systems at ASMS 2024. Designed to target the food and environmental markets, these systems offer unmatched precision and sensitivity, addressing critical analytical challenges.

Such advancements exemplify the sector's commitment to innovation, driving market expansion. With each new product launch, mass spectrometry becomes more versatile, fostering its adoption across various scientific and industrial applications.

Market Restraining Factor

High cost of instruments & associated service

The high cost of mass spectrometry instruments and related services acts as a significant restraint on market growth. Advanced instruments, developed through continuous R&D, are priced at a premium due to their sophisticated technology and precise analytical capabilities. This financial burden is further amplified by the high service costs associated with their usage and maintenance.

For instance, the service cost for utilizing LC-MS and GC-MS instruments is approximately $200.57 per sample, making their adoption challenging, especially for small and mid-sized laboratories. These expenses limit accessibility and restrict broader adoption across industries. The high cost of ownership, combined with recurring operational expenses, creates a financial barrier, ultimately hindering the market’s overall expansion potential.

Mass Spectrometry Market Opportunities

Development of miniaturized and portable systems

Traditional mass spectrometers are often large and require high-vacuum environments, limiting their use in field applications and making them less accessible to a broader user base. However, the development of miniaturized and portable mass spectrometry systems is expanding the scope of applications and attracting new user groups. These portable systems enable on-site analysis in industries such as environmental monitoring, forensic science, and food safety, breaking the constraints of laboratory-bound equipment.

  • For instance, in January 2024, researchers at MIT explored the potential of 3D-printed portable mass spectrometers designed for remote access. This innovation allows researchers to conduct high-precision analyses in remote or resource-limited locations, significantly enhancing flexibility and accessibility.

The portability of these advanced systems benefits researchers by enabling real-time data collection and analysis, fostering faster decision-making processes. This growing trend is unlocking new opportunities for market expansion, highlighting the increasing demand for accessible, field-ready mass spectrometry solutions.

Study Period 2021-2033 CAGR 6.7%
Historical Period 2021-2023 Forecast Period 2025-2033
Base Year 2024 Base Year Market Size USD 6.93 billion
Forecast Year 2033 Forecast Year Market Size USD 12.33 billion
Largest Market North America Fastest Growing Market Asia-Pacific
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Regional Insights

North America: Dominant region with 41.68% market share

North America holds the largest revenue share in the global mass spectrometry market, driven by substantial investments in research and development for technological advancements and the rising demand for innovative technologies in healthcare and clinical diagnostics. The region’s strong focus on leveraging mass spectrometry for groundbreaking applications in healthcare is accelerating its growth.

  • For instance, in June 2024, Thermo Fisher Scientific launched a state-of-the-art mass spectrometer designed to transform basic scientific discoveries into clinical applications, ultimately improving patient outcomes.

This leadership is further supported by a well-established healthcare infrastructure, a robust pharmaceutical industry, and a proactive approach to adopting advanced diagnostic tools, ensuring North America’s continued dominance in the market.

Asia-Pacific: Rapid growth in China, Japan, and India

Asia Pacific is expected to register the fastest CAGR, driven by rising investments in healthcare infrastructure, an expanding pharmaceutical and biotechnology industry, and increasing funding for research and development. Strategic expansions further fuel regional growth. For instance, in 2024, AbbVie announced a $223 million investment to expand its biologics manufacturing facility in Singapore, set for completion by 2026.

Moreover, Thermo Fisher Scientific inaugurated a sterile drug manufacturing facility in Singapore to bolster R&D and production for the Asia Pacific market, reflecting the region’s growing significance in the global industry.

Countries Insights

  • U.S. –The U.S. market maintains its leadership due to significant investments in research and development, along with its advanced healthcare infrastructure. The presence of major industry players such as Agilent Technologies, Shimadzu Corporation, Danaher, and Thermo Fisher strengthens its market position. These companies continue to invest heavily in innovation and technological advancements, ensuring that the U.S. remains a key driver with continuous development in both healthcare and scientific applications.
  • Canada -Canada's commitment to research and development fuels growth in its market. The Canadian government actively supports scientific initiatives through funding, empowering researchers to adopt advanced technologies and create innovative products. For example, in March 2024, Queen’s University researchers received $40 million in government funding to advance research in human health and materials discovery. This support plays a crucial role in expanding the use of mass spectrometry for diverse applications in healthcare and materials science.
  • Germany–Germany's thriving pharmaceutical and biotechnology sectors contribute significantly to the growth of the mass spectrometry industry. The presence of global industry leaders and substantial investments by companies like Roche ensures that Germany remains at the forefront. In 2023, Roche invested $1.46 billion to enhance its German facilities, including locations in Mannheim and Penzberg. Such investments foster innovation and create demand for advanced tools, accelerating the market's expansion in both research and production environments.
  • UK -The United Kingdom plays a pivotal role in advancing the market through government-backed research and development initiatives. The integration of novel technologies into mass spectrometry systems is crucial, and the UK government funds projects that drive innovation. For instance, in May 2024, the Critical Mass (C-Mass) project received $51.31 million in funding from UK Research and Innovation, aimed at advancing the UK’s capabilities in mass spectrometry, which will help the country maintain its competitive edge in scientific research.
  • France -France's market is witnessing growth due to increasing investments from market players aiming to expand their product portfolios. In September 2024, bioMérieux, a global leader in in-vitro diagnostics, inaugurated a new-generation R&D building in France, signaling ongoing advancements in the healthcare sector. This continued investment strengthens France's position in the global mass spectrometry landscape, fostering growth by enhancing both research capabilities and the availability of advanced diagnostic tools in the country.
  • Japan –Japan's expanding pharmaceutical and biotechnology industries are driving the growth of the market for mass spectrometry. As major players in these sectors continue to expand their product portfolios, demand for advanced analytical tools like mass spectrometers increases. In 2024, AGC Biologics unveiled plans for a new biologics and advanced therapies facility in Japan. This expansion will boost the need for mass spectrometry in research and product development, fueling market growth in the region.
  • India–India, with the second-largest pharmaceutical industry by volume globally, is emerging as a key market for mass spectrometry. The growing pharmaceutical and biotechnology sectors generate substantial demand for advanced analytical tools. In 2024, 93 new projects were reported in India’s pharmaceutical, biotech, and life sciences sectors, driving the need for mass spectrometry in sample analysis and product development. This expansion positions India as a significant contributor to the market's growth in the coming years.
  • Australia –Australia continues to lead in research, making it a prominent market for advanced technologies, including mass spectrometry. The country’s focus on scientific discovery and innovation fosters growth in various sectors, including healthcare and environmental analysis. In August 2024, AXT introduced disruptive mass spectrometry technology to Australia, enhancing the country's capabilities in scientific research and analysis. This move strengthens Australia's position as a leader in adopting and integrating cutting-edge technologies, driving regional market expansion.
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Segmentation Analysis

The global mass spectrometry market is segmented into technology, sample preparation, and application.

By Technology

Quadrupole mass spectrometry segment dominates the market with the largest market revenue

The quadrupole segment dominates the market due to its high selectivity, superior signal-to-noise ratio, and reliable analyte identification through multiple reaction monitoring. These features ensure precise quantitation and enhanced performance. Moreover, quadrupole systems are cost-effective and available in advanced configurations, such as triple quadrupoles with expanded linear quantitation ranges. For instance, in June 2022, Agilent launched a revolutionary triple quadrupole LC/MS system, exemplifying ongoing technological advancements that sustain this segment’s leadership.

By Sample Preparation

LC-MS segment dominates the market with the largest market revenue

The LC-MS segment leads the global market, driven by its high sensitivity and critical role in the pharmaceutical industry, which primarily involves liquid sample analysis. With increasing investments in pharmaceutical and biologics R&D, the demand for LC-MS systems continues to rise. These instruments offer unmatched precision in detecting and analyzing liquid samples, aligning with the industry's evolving needs. The segment's dominance reflects its indispensable role in advancing pharmaceutical research and development.

By Application

Pharma & bio-pharma segment dominates the market with the largest market revenue

The pharma and bio-pharma segment dominates the market due to mass spectrometry's extensive applications in drug discovery, development, and quality control. From the initial stages of research to final product testing, mass spectrometry ensures accuracy and reliability. The post-COVID-19 surge in pharmaceutical and biotech activities has further amplified demand. As these industries continue to grow and innovate, mass spectrometry remains integral, solidifying the pharma and bio-pharma segment's market leadership.

Market Size By Technology

Market Size By Technology
Time-of-Flight (TOF) Quadrupole Mass Spectrometry Ion Trap Mass Spectrometry Orbitap Fourier Transform Mass Spectrometry (FTMS) Others

List of key players in Mass Spectrometry Market

  1. Agilent Technology
  2. Shimadzu Corporation
  3. Danaher
  4. Thermo Fisher
  5. Bruker
  6. PerkinElmer
  7. Waters Corporation
  8. LECO Corporation
  9. SCIEX
  10. CAMAG
  11. JASCO
  12. In Zybio Inc. 
  13. Pfeiffer Vacuum+Fab Solutions
  14. SEPSOLVE
  15. Sercon
Mass Spectrometry Market Share of Key Players

Company Market Share

Key players in the global market are increasingly pursuing strategic collaborations, acquisitions, and partnerships to enhance their product offerings, expand their technological capabilities, and broaden their market reach. These strategic moves not only help key players meet the rising demand for more efficient and accurate mass spectrometry systems but also enable them to respond to the evolving needs of industries such as healthcare, environmental analysis, and pharmaceuticals.

SepSolve: An emerging provider in the global mass spectrometry market

SEPSOLVE is an emerging player in the global market, recognized for its innovative product offerings, including TOF-MS and advanced hard and soft (tandem) ionization techniques. These products are designed to provide highly accurate and efficient analysis across various applications, from healthcare to environmental monitoring.

Recent Development by SepSolve:

In May 2024, SepSolve Analytical announced a strategic partnership with HyperChrom SA to bring together HyperChrom’s fast gas chromatography (GC) and SepSolve’s BenchTOF2™ time-of-flight mass spectrometer (TOF MS).

Recent Developments

  • October 2024 –MOBILion Systems unveiled novel high-resolution mass spectrometry functionality, marking a paradigm shift in proteomics workflows. The new technology significantly improves speed and sensitivity, enabling researchers to perform complex analyses faster and with greater precision.
  • June 2024 –Shimadzu announced the release of a new LC-MS triple quadrupole mass spectrometry series designed to enhance reliability and analytical performance. The new systems feature optimized gas flow and improved nebulizer coaxiality, resulting in better sensitivity, precision, and robustness in various applications.

Analyst Opinion

As per our analysts, the global market is experiencing significant expansion, driven by its increasing applications across diverse industries. Key factors propelling this growth include its widespread use in healthcare and clinical diagnostics, food safety and environmental testing, as well as the analysis of samples in the pharmaceutical and biotechnology sectors.

The robust growth of these industries further amplifies the demand for mass spectrometry, providing a broader scope for market expansion. Moreover, ongoing technological advancements are revolutionizing the field, delivering enhanced precision, speed, and reliability, which benefit researchers and enable breakthroughs in complex analyses.

These developments, coupled with the versatility of mass spectrometry in addressing evolving analytical challenges, position the market for sustained growth in the coming years.

 


Mass Spectrometry Market Segmentations

By Technology (2021-2033)

  • Time-of-Flight (TOF)
  • Quadrupole Mass Spectrometry
  • Ion Trap Mass Spectrometry
  • Orbitap
  • Fourier Transform Mass Spectrometry (FTMS)
  • Others

By Sample Preparation (2021-2033)

  • LC-MS
  • GC-MS
  • Others

By Application (2021-2033)

  • Pharma & Bio-pharma
  • Food and Beverage Testing
  • Environmental Testing
  • Clinical
  • Academic
  • Others

Frequently Asked Questions (FAQs)

How big is the Mass Spectrometry Market?
Straits research predicts that the global mass spectrometry market size was valued at USD 6.93 billion in 2024 and is projected to grow from USD 7.33 billion in 2025 to reach USD 12.33 billion by 2033.
The global market growth rate growing at a 6.7% from 2025 to 2033.
Increasing investments in R&D of pharmaceutical industries, is a key growth factor driving advancements in global market.
North America holds the largest market share in global market
Currently, Pharma & bio-pharma segment dominates the market with the largest market revenue.


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