A minimally invasive treatment called renal denervation is used to treat resistant hypertension. The primary contributors to the growth of the renal denervation devices market are the increasing elderly population, the rising prevalence of hypertension, and the procedure's long-lasting effects.
The prevalence of hypertension-related illnesses and chronic conditions continues to increase globally. Hypertension, commonly known as high blood pressure, is a severe medical condition that significantly raises the chance of developing heart, kidney, brain, and other disorders. In 2018, the Centers for Disease Control and Prevention (CDC) reported that high blood pressure was a primary cause of death for more than 494,873 Americans, with over 100 million suffering from the illness. An increase in hypertension cases is anticipated to generate demand for renal denervation devices during the projected period.
According to the United Nations Department of Economics and Social 2019 report, it was estimated that by the year 2050, 16% of the global population would be over 65, up from 9% in 2019. By 2050, one in four people in Europe and Northern America could be 65 or older. In 2018, people aged 65 and over outnumbered children under five globally for the first time in history. The number of people aged 80 and older is anticipated to treble between 2019 and 2050, from 143 million to nearly 426 million. The percentage of the population aged 65 or older virtually doubled from 6% in 1990 to 11% in 2019 in Eastern and South-Eastern Asia and from 5% in 1990 to 9% in 2019 in Latin America and the Caribbean, according to the same survey. In four regions, namely Central and Southern Asia, Northern Africa and Western Asia, Eastern and South-Eastern Asia, and Latin America and the Caribbean, the percentage of the elderly is anticipated to quadruple.
It is anticipated that the number of individuals suffering from hypertension will increase as the global population ages. Hypertension is caused by aging-related arterial stiffness, hemodynamic alterations, neurohormonal and autonomic dysregulation, and diminishing the renal function. Consequently, all of the considerations mentioned above suggest that an increase in hypertension cases would drive demand for renal denervation devices over the projection period, thereby boosting the growth of the analyzed market.
Innovative research in fields such as hypertension has also led to the expansion of new commercial prospects. In February 2020, Ablative Solutions, Inc. published favorable research results regarding the safety and efficacy of its CE-marked Peregrine System Infusion Catheter. The study determined that the renal denervation treatment utilizing the Peregrine Catheter and alcohol as a neurolytic agent is safe and effective and can reduce blood pressure in patients with poorly managed hypertension on medication.
The number of firms shaping the future of Renal Denervation Devices is increasing. As the healthcare industry pushes toward minimally invasive surgeries, a growing interest is in developing solutions for hypertension treatment, which is projected to lead to market growth. Future growth potential for the market for denervation devices is likely to be significantly influenced by the reasons mentioned above.
Europe accounts for the largest market share and is estimated to grow at a CAGR of 37.5% during the forecast period. The growth is attributable to the rising geriatric population. The spiking cases of therapy-resistant hypertension are also a key factor driving the market. Hypertension is one of the most common diseases in Europe. Changes in lifestyle, such as excessive alcohol consumption, lack of physical activity, smoking, and consumption of fast food, increase the risk of hypertension. The increased blood pressure subsequently gives rise to various diseases, such as stroke, heart attacks, and pulmonary arterial hypertension. The increasing prevalence of smoking in Germany is also causing hypertension, increasing the demand for renal denervation devices.
Asia-Pacific is estimated to account for USD 90 million by 2030, registering a CAGR of 37.6%. The market is anticipated to expand in the region because of the rising prevalence of hypertension and increasing awareness of the treatment's benefits. Renal denervation can selectively ablate renal sympathetic nerve fibers and prevent the transmission of nerve impulses between the central sympathetic nerve and kidney to control blood pressure as a unique, promising non-drug therapeutic option for hypertension resistant to drug therapy. Increasing research into the treatment's efficacy is the primary driver of the anticipated market expansion. Therefore, the increasing prevalence of hypertension and cardiovascular disorders increases the desire for appropriate treatment, raising the country's demand for the devices.
North America is the third largest region. The increasing prevalence of hypertension, the changing lifestyle, the growing senior population, and the long-lasting effect of the surgery may lead to a sharp increase in demand. Domestic enterprises are employing numerous techniques to increase their market position, including R&D, mergers and acquisitions, and product launches. In 2020, the US-based company ReCor Medical Inc. announced that it is Paradise Ultrasound Renal Denervation System has achieved Breakthrough Device Designation from the FDA. The renal nerve is ablated using ultrasonic energy using the Paradise system. Consequently, the increasing prevalence of hypertension, the ongoing development of the industry, and the adoption of new technologies by market participants in the country are anticipated to stimulate the expansion of the market under study.
In June 2024, DeepQure, a Korean medtech firm introduced an early feasibility study for its HyperQure renal denervation device to treat resistant hypertension.
As per our analyst, renal denervation devices are situated at a critical juncture in the hypertension treatment landscape. Market revenue projections for these devices remain optimistic, largely fueled by the rising incidence of resistant hypertension and a growing patient population seeking alternatives to traditional pharmacotherapy.
Despite this potential, the market is tempered by challenges such as high device costs and inconsistent clinical trial outcomes, which can affect adoption rates and investor confidence. For sustained growth and market penetration, renal denervation devices must address the financial and clinical challenges while demonstrating unequivocal efficacy and cost-effectiveness to healthcare providers and payers.