Global Research-grade Proteins Market Revenue Grows at a CAGR of 15.88%.

Introduction

Straits Research released its highly anticipated report, “Global Research-grade Proteins Market Size & Outlook, 2026-2034”. According to the study, the market size is valued at USD 1126.67 million in 2025 and is anticipated to grow till USD 4231.16 million by 2034, growing at a CAGR of 15.88% from 2026-2034.

Market Dynamics

The research-grade proteins market is expanding steadily as laboratories incorporate specialized protein reagents into a diverse range of molecular, cellular, and translational studies. A key driver for this market is the rapid growth of advanced experimental systems that depend on highly controlled protein inputs to study signaling pathways, receptor dynamics, and disease-related mechanisms with greater experimental precision. As research programs adopt more sophisticated platforms, demand for proteins with consistent structural and functional attributes continues to accelerate across pharmaceutical companies, biotechnology firms, and academic laboratories.

A restraint in the market stems from variability in protein production quality across different expression systems and purification conditions. Inconsistencies in folding, post-translational characteristics, or activity levels can introduce additional verification steps for researchers, prolonging project timelines and increasing the complexity of assay development. These variations become more challenging in experiments where even minor deviations in protein performance can influence downstream biological responses or model behavior, creating limitations for teams aiming to maintain uniform experimental conditions.

Despite these challenges, the market presents a substantial opportunity through the growing establishment of specialized protein foundries focused on custom synthesis. These centers harness advanced expression technologies and characterization tools to deliver tailored protein constructs suited for niche research objectives, including rare variants, engineered domains, or proteins modified for enhanced stability. As custom synthesis becomes more accessible across global research networks, laboratories gain wider access to in-depth protein libraries that support new investigative directions in structural biology, functional genomics, cell therapy development, and therapeutic exploration, strengthening long-term market potential.

Market Highlights

• Product: Based on product, the Cytokines and Growth Factors segment held the highest revenue share of 25.52% in 2025.
• Host Cell: Based on the host cell, the Mammalian Cells segment dominated the market with 58.12% in 2025.
• End Use: By end use, the Pharmaceutical and Biotechnology Companies segment held the largest market share of 62.34% in 2025.
• Regional Insights: North America held a dominant share of the global market, accounting for 45.84% in 2025.

Competitive Players

1. Thermo Fisher Scientific Inc.
2. Merck KGaA
3. Merck
4. Bio-Techne
5. Abcam Limited
6. R&D Systems, Inc. 
7. Promega Corporation
8. Sino Biological, Inc. 
9. GenScript
10. Lonza
11. Cytiva
12. BD
13. New England Biolabs
14. Rockland Immunochemicals, Inc.
15. ACROBiosystems
16. Novus Biologicals
17. Others

Recent Developments

October 2025: Qkine, Ltd.,  announced the launch of its cell therapy grade proteins, engineered to support the stringent requirements of cell therapy research, process development, and GMP manufacturing.

Segmentation

1. By Product (2026-2034)
   1. Cytokines & Growth Factors
      1. Interferons (IFNs)
      2. Interleukins (ILs)
      3. Others
   2. Antibodies
   3. Immune Checkpoint Proteins
   4. Virus Antigens
   5. Enzymes
      1. Kinases
      2. Metabolic Enzymes
      3. Others
   6. Recombinant Regulatory Proteins
   7. Hormones
   8. Others
2. By Host Cell (2026-2034)
   1. Mammalian Cells
   2. Bacterial Cells
   3. Yeast & Fungi
   4. Insect Cells
   5. Others
3. By End Use (2026-2034)
   1. Pharmaceutical & Biotechnology Companies
   2. Academic & Research Institutes
   3. Others