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Anti-HIV Drugs Market: Information by Medication Class (Nucleoside Reverse Transcriptase Inhibitors (NRTIS)), Distribution Channel (Hospital Pharmacies), Region — Forecast till 2029

Market Snapshot
Study Period:
Base Year:
Fastest Growing Market:
Largest Market:
North America
6.2 %
Key Players
Gilead Sciences IncSciences Inc.

ViiV Healthcare

Merck & Co. Inc.


Hoffmann-La Roche Ltd.

Market Overview

 Globally, the prevalence of HIV has been increasing at a concerning rate, which is subsequently increasing testing procedures for HIV and the development of anti-HIV drugs with high efficacy and potency. The anti-HIV drug market is one of the fastest-growing markets across the globe.


An increasing number of infection transmission through contaminated needles and infected blood is subsequently rising the prevalence of HIV across the globe. Currently, HIV infection is treated using nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), entry and fusion inhibitors, integrase inhibitors, and protease inhibitors (PIs). Some of the prominent drugs available in the market include Truvada, Atripla, Stribild, and Prezista/Prezcobix.

The Global anti-HIV drugs market was valued at USD 26,883.4 million in 2019 and is expected to grow with a CAGR of 6.2%.


Unavailability of Effective Drugs and High Price of Anti-HIV drugs

In Sub Saharan Africa, the rising prevalence of HIV, unavailability of effective drugs, low income, and the high price of anti-HIV drugs prompt the dire need for affordable anti-HIV drugs in the region. As per the data published by the UNAIDS, globally, around 39.7 million people had HIV, and about 1.7 million people died of HIV in 2018. The disease is highly prevalent in developing and underdeveloped countries due to a lack of adequate prevention measures and treatment facilities. The unmet treatment needs and therapeutics in the Asian and African countries provide lucrative opportunities for market growth. The following table depicts the increasing prevalence of HIV and people receiving anti-HIV therapies globally.


Rapid Development of Effective Anti-HIV Drugs by Prominent Players

Globally, the prominent market players, such as Gilead Sciences IncSciences, Inc., GSK, Merck & Co., Inc., Roche, Boehringer Ingelheim, are performing extensive research to develop new products to address the growing demand for effective drugs. The players are also leveraging innovative technologies such as cell therapy and immunomodulation for new drug development. The launch of such innovative drugs in the market is creating lucrative opportunities for the anti-HIV drug market during the forecast period. The following graph depicts the pipeline for anti-HIV drugs by Gilead Sciences Incsciences Inc.


Government Initiatives to Raise Awareness Regarding Diagnosis and Treatment of HIV

Governments and organizations across the globe are actively working to raise awareness regarding HIV and organizing several campaigns to increase community awareness regarding treatment and care. In the U.S., the federal government launched a five-year initiative in 2010, the National HIV/AIDS Strategy, to control the prevalence of HIV and increase access to anti-HIV therapies. In July 2015, the federal government extended the National HIV/AIDS Strategy until 2020.

In India and Brazil, the governments have launched the National AIDS Control Program and the Brazilian HIV/AIDS Programme, respectively, to increase awareness regarding HIV and its treatment options. Thus, increasing awareness about the diagnosis and treatment of HIV is subsequently surging the adoption of effective treatment options, further driving the market growth. The following figure depicts the global and domestic financial resource mobilization in for HIV treatment.


Anti-HIV Drugs Market: Segmentation

Increasing Drug Resistance to Drive the Demand for Multi-Class Combination Drugs

The multi-class combination drugs segment held the largest market share as the HIV treatment requires the combination of anti-HIV drugs belonging to different drug classes. Currently, the U.S. FDA has approved more than 20 drugs, which are commercially available in the market. Single drug therapies often lead to treatment failures due to drug resistance. On the other hand, the multi-drug combinations have better efficacy in inhibiting the multiple aspects of HIV transmission, further driving its adoption across the globe. The multi-class combination drugs can target incoming viral load, virus-infected cells, and cells susceptible to HIV infection, further driving the market growth.

Increasing FDA Approval to Drive NRTIs Segment Growth

The NRTIs segment is expected to grow at a significant rate during the forecast period. NRTIs acts by inhibiting reverse transcriptase activity, ultimately terminating the viral replication. Currently, the U.S. FDA has approved about seven NRTIs for HIV treatment, which includes Zidovudine (Retrovir), Lamivudine (Epivir), Abacavir sulfate (Ziagen), Didanosine (Videx), Delayed-Release Didanosine (Videx EC), Stavudine (Zerit), and Emtricitabine.

Rapid Product Launches by Prominent Market Players to Drive the Segment Growth

The HIV integrase strand inhibitors segment is projected to witness the fastest growth on account of rapid product launches by prominent market players such as Gilead Sciences Inc. and Merck & Co., Inc. Currently, BI 224436 HIV integrase inhibitor developed by Gilead Sciences IncInc. is under phase II clinical trial. Similarly, Cabotegravir developed by GSK is also under clinical trial.

Easy Access to HIV Drugs to Drive the Hospital Pharmacies Segment

The hospital pharmacies segment held the largest market share in 2018 due to increasing awareness regarding HIV drugs and improving healthcare infrastructure in both developed and developing countries. The hospital pharmacy stores offer easy access to HIV drugs as they supply time-bound medicines for critically ill HIV patients. They also enable hospitals to provide quality anti-HIV drugs by directly purchasing from drug manufacturers, thus avoiding the problem of counterfeit medicines.  

Impact of COVID 19

The COVID-19 outbreak has placed enormous strain on the global supply of anti-HIV drugs due to disruption in supply chain and drug shortages. Globally, several HIV drug manufacturers are manufacturing medications for the treatment of COVID 19, further hampering the market growth. Prominent players, such as Gilead Sciences Incand Eli Lilly, are arduously working to develop innovative medicines to address the rising prevalence of COVID-29 and expand their product portfolio. In March 2020, Remdesivir developed by Gilead Sciences Increceived orphan drug status from the U.S. FDA.

Regional Overview


Strong Presence of Leading Market Players to Drive North America’s Anti-HIV Market Growth

North America dominates the anti-HIV drugs market as the region possesses the presence of leading market players that are actively working to develop innovative drugs with improved efficacy such as Complera by Gilead Sciences Inc. As per the U.S. Department of Health & Human Services, around 1.1 million people aged 13 and above had HIV in 2016. As per the latest estimates from the Centers for Disease Control and Prevention (CDC), in 2018, around 37,832 new cases of HIV were registered in the U.S.

As per Canada’s Source for HIV, the CATIE, in 2015, around 75,500 Canadians have HIV, and the prevalence rate has increased by 9.7% since 2011. The National Institutes of Health (NIH) in the U.S., represents the largest public investment in HIV research in the world, further driving the market growth. Thus, the rising prevalence of HIV and the strong presence of dominant market players drive regional market growth. The following graph illustrates the anti-HIV drug market dynamics in the U.S.


Government Initiatives in India and China to Drive Asia-Pacific’s Market Growth

Asia-Pacific is expected to witness the fastest growth in the anti-HIV drug market. Rising healthcare spending, favorable government regulations, and the high presence of unmet drug demand in India and China drive the market growth. As per the AVERT, an international HIV and AIDS charity organization, in 2015, about 5.1 million people had HIV in Asia; of which only 64% were diagnosed with HIV. In the same year, around 180,000 people died of HIV in Asia. Governments in India and China are organizing several awareness programs to raise awareness regarding HIV and its treatment options, further driving the market growth.

Key Players

  • Gilead Sciences IncSciences, Inc.
  • ViiV Healthcare
  • Merck & Co., Inc.
  • AbbVie
  • Hoffmann-La Roche Ltd.
  • Teva Pharmaceutical Industries Ltd.
  • Bristol-Myers Squibb
  • Pfizer
  • Shionogi
  • Cipla Limited
  • Boehringer Ingelheim International GmbH

Recent Developments

  • In July 2019, Merck announced the launch of new drug candidate Islatravir (MK-8591) nucleoside reverse transcriptase translocation inhibitor (NRTTI) for HIV treatment
  • In April 2019, Viiv healthcare received the U.S. FDA approval for Dovato (dolutegravir and lamivudine combination), a single tablet containing a two-drug regime for HIV treatment

Anti-HIV Drugs Market Segmentation

By Medication Class

  • Multi-class combination drugs
  • Nucleoside reverse transcriptase inhibitors (NRTIs)
  • Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
  • HIV integrase strand transfer inhibitors

By Distribution Channel

  • Hospital pharmacies
  • Retail pharmacies
  • E-commerce

By Region

  • North America
  • Europe
  • Asia-Pacific
  • South America
  • The Middle East and Africa

Frequently Asked Questions (FAQs)

Multi-Class Combination Drugs Segment is expected to be the leading segment in Anti-HIV Drugs Market during the forecast period.
The anti-HIV market was valued at USD 26,883.4 million in 2019 and is expected to grow with a CAGR of 6.2%.
Gilead Sciences IncSciences, Inc., ViiV Healthcare, Merck & Co., Inc., AbbVie, F. Hoffmann-La Roche Ltd., Bristol-Myers Squibb, Pfizer, Shionogi are the top players in Anti-HIV Drugs Market.
North America is expected to hold the highest market share in Anti-HIV Drugs Market.
increasing awareness about the diagnosis and treatment of HIV is subsequently surging the adoption of effective treatment options are the key factors expected to drive Anti-HIV Drugs Market during the forecast period.
In 2019 Global Anti-HIV Drugs Market was valued at USD 26,883.4 million.
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