Bioabsorbable Stents Market

Market Overview

The global bioabsorbable stents market size was valued at USD 216 million in 2021. It is anticipated to generate USD 365 million by 2030, growing at a CAGR of 5.95% during the forecast period (2022–2030).

Bioabsorbable stents are a specific form of a stent that can disintegrate or reabsorb within the body of the patient. Stents come in a variety of sizes, shapes, and materials. These are employed in various therapeutic situations, including esophageal cancer, gall bladder cancer, and cancers of the abdomen and gastrointestinal system. However, bioabsorbable stents are most commonly used to treat cardiac problems like clogged blood arteries.

The bioabsorbable stents assist in the restoration of blood flow and provide support to the blood vessel during the healing process. Furthermore, these stents reabsorb or disappear from the treated location on their own after a few days, which offers advantages such as less late-stent thrombosis. These stents are compatible with pediatric surgery, requiring no additional surgical removal and allowing for artery expansion. Polylactic acid, a naturally dissolving substance, is used in most of these stents.

Market Dynamics

Market Drivers

• Growing Heart Disease and Geriatric Populations soaring Market Growth

One of the significant drivers of market growth is the accessibility of bioabsorbable stents for percutaneous coronary intervention procedures (PCI) in patients with heart diseases such as coronary artery disease and peripheral arterial disease. Heart disease is the leading cause of death and morbidity worldwide. According to the World Health Organization (WHO), cardiovascular illnesses caused 17.9 million deaths in 2018.

According to the American College of Cardiology (AHA), coronary artery disease in the United States was 1,055,000 people in 2019, with 335,000 recurrent cardiovascular events and 720,000 new cases. Three-quarters of deaths from heart disorders occur in low to middle nations. The rise in the global elderly population is also a significant driver driving the global bioabsorbable stent market, as older people are more prone to cardiovascular disease. Since aging causes changes in the blood vessels present in the heart, people over the age of 65 are more likely to acquire coronary artery disease than younger people.

According to the Centers for Disease Control and Prevention (CDC), 10.9% of people over the age of 45 have been diagnosed with coronary artery disease (CAD), with 7.1% of adults between the ages of 45 and 65 and 17% of adults over the age of 65 having been diagnosed. As a result, the rising frequency of heart illness, combined with an aging population, is driving up the need for bioabsorbable stents.

• Advances in Bioabsorbable Stent Technology

In the global healthcare market, bioabsorbable stents play a significant role. It is expected to grow throughout the forecast period, owing to technological improvements and increased usage of new bioabsorbable stents. Physicians employ these devices to perform cardiac surgery on patients, such as percutaneous coronary intervention (PCI) operations. Several newer technologies are gaining traction and being utilized by various healthcare practitioners. With the help of bioabsorbable stents, correct blood flow will be restored, and blood will gradually be reabsorbed in the body, allowing for natural restoration of vascular function and repair of artery walls.

In April 2019, for example, Arterius Limited partnered with the Translational Biomedical Research Centre to create novel bioabsorbable stents and eliminate the risk associated with metal stents. The increased risk of restenosis and late stent thrombosis related to traditional stent use encourages the adoption of bioabsorbable stents. Bioabsorbable stents are organic and natural and are used to treat gastrointestinal cancer, gallbladder cancer, and esophageal cancer, among other clinical conditions. It employs a variety of polymeric materials, namely polyglycolic acid, poly-L-lactic acid, polycaprolactone, and poly (D, L-lactide/glycolide) copolymer, which has both scaffolding and drug delivery properties.

Abbott has introduced a bioabsorbable everolimus-eluting stent, which is made up of two different types of polymer and has the ability to reabsorb after 18 months. Bioabsorbable stents decrease the risk of many procedures such as acute and sub-acute elastic recoil, intimal hyperplasia and adverse vascular remodeling, and balloon angioplasty coronary dissections. As a result of these technological breakthroughs in bioabsorbable stents, the market is projected to expand.

• Increased Demand for Minimally Invasive Treatment

The global market is expected to develop due to the rising need for minimally invasive surgical procedures and increased usage of percutaneous coronary intervention procedures. A minimally invasive surgical procedure is one in which a little incision replaces a large hole. Percutaneous coronary intervention is a minimally invasive surgical treatment in which angioplasty is performed, and bioabsorbable stents are implanted in the patient's body.

MicroPort Scientific Corporation, for example, developed the Castor Branched Stent-Graft system in April 2021, which can be used to treat aortic arch repair using a less invasive surgical method. According to the most recent data from interventional cardiology procedural analysis, roughly 965,000 angioplasty procedures were performed in the United States per year in 2020. In addition, the Centers for Medicare and Medicaid Services (CMS) added angioplasty to the list of 17 cardiac procedures allowed by Ambulatory Surgical Centers (ASC) in 2019. Furthermore, by 2026, percutaneous coronary intervention (PCI) treatments are anticipated to reach one million. As a result, the demand for percutaneous coronary intervention (PCI), a less invasive technique, is booming.

• R&D and Healthcare Infrastructure Growth

The government has provided ideal conditions for the growth of healthcare infrastructure over the last decade. The government boosted its spending on the healthcare business, which is a vital component in the expansion of healthcare infrastructure and pushes the growth of bioabsorbable stents. For example, in February 2021, India's government increased healthcare spending from 1.2% to 2.5% of GDP, intended to be invested in modernization and the establishment of healthcare infrastructure.

The global market is growing due to an increase in investment and activity in R&D by various medical fields to discover and develop new solutions for bioabsorbable stents with precision and rapid response. Investment in the R&D sector is a venture strategy for generating unique products and long-term company and development growth.

According to the United Nations Educational, Scientific, and Cultural Organization (UNESCO) data, global R&D investment has surpassed USD 1.7 trillion, with around ten countries accounting for 80% of the total. The market is expected to rise during the projected period due to government regulations governing the design and deployment of sophisticated stents, including bioabsorbable stents.

Market Restraints

• High Procedural Cost linked with Bioabsorbable Stents

Due to the high expense of a procedure connected with the bioabsorbable stent, bioabsorbable stent adoption is expected to be limited. According to statists, the average cost of an angioplasty procedure in 2019 was roughly USD 28,200 million. In developing nations, where many people lack health insurance, the high price is a significant impediment. According to the World Bank and the World Health Organization, half of the world's population did not have access to essential health services in 2017. As a result, this factor is expected to limit the market growth during the forecast period.

• Risk of Bioabsorbable Stents

There's a potential that bioabsorbable stents will cause some harmful effects. The manufacturers of bioabsorbable stents have been forced to pull their products due to the substantial danger connected with the device. For example, Abbott recalled Absorb worldwide in 2017 due to risks such as cardiac infarction and thick strut. The trouble is related to the non-uniform structure of the polymer utilized in the stents, which causes the device's flow to be disrupted. As a result, these risk concerns may negatively influence the market growth during the projection period.

Growth Opportunities

• Improved R&D and Technological Advancements

Treatment of coronary artery disease and peripheral arterial disease, intertwined with notions of rising technologies and a surge in R&D expenditure, gives high precision and provides accurate responses. The notion of bioabsorbable stents has been around for over 20 years; however, there are still numerous obstacles to overcome in generating bioabsorbable stents with adequate radial strength and reabsorption that does not cause an inflammatory reaction.

Abbott continued its research after the first bioabsorbable stent was withdrawn from the market in 2017. In 2020, it released the Esprit BTK bioabsorbable stents, which are utilized to resist vascular recoil and provide medication delivery systems. Clinical trials are being conducted to assess the BRS devices' safety and efficacy. Researchers are also addressing Absorb's drawbacks, such as myocardial infarction and thick strut, intending to develop a new bioabsorbable stent that avoids these risks. As a result, the market for bioabsorbable stents is predicted to grow due to the increased acceptance of innovative technologies and increased R&D activities.

Segmental Analysis

The global bioabsorbable stents market share is categorized by biomaterials, applications, and end-users.

Based on the Types of Biomaterials Used

The two subsegments are polymeric stent and metallic stent. The polymeric stent is the major shareholder in the global bioabsorbable stents market. As a result of a growth in the number of approvals granted by the government and an increase in the prevalence of cardiovascular disorders, it is anticipated that the market will expand significantly over the next few years. Companies intend to produce polymeric stents. The global market for polymeric stents is projected to generate USD 194 million at a CAGR of 5.4% by 2030.

Metallic bioabsorbable stents comprise iron, zinc, and magnesium with a strong alloy. Zinc in bioabsorbable stents prevents biofilm growth. Metallic stents can cause thrombosis and restenosis. Metallic stents take longer to absorb and may cause restenosis; thus, doctors and patients prefer plastic. Owing to these factors, the market for metallic stents is facing slow growth.

By Application-Wise

The most significant share of the global bioabsorbable stents market is held by coronary artery disease due to demographic shifts toward an unhealthy lifestyle, an aging population, and an increase in the incidence of diabetes cardiovascular disease. The global market for coronary artery disease is projected to generate USD 278 million at a CAGR of 6.7% by 2030. Peripheral artery disease was valued at USD 62 million in 2021. A significant element to the expansion of the market is the rising incidence of the elderly population, the growing incidence of smoking, the prevalence of high blood pressure, and the adoption of unhealthy lifestyles.

The global bioabsorbable stents market is segmented as hospitals and cardiac centers based on the end-users. Hospital is the highest market shareholder. Due to an increase in coronary artery disease, a drop in the expense of post-operative cardiac care, and an increase in the life expectancy of patients suffering from cardiac disease, this subsegment is predicted to grow significantly during the projection period. The global market for the hospital is projected to generate USD 330 million at a CAGR of 6.2% by 2030. The cardiac center held a market share of USD 24 million in 2021. The market's growth is fueled by a rise in demand for quality of life, an increase in the frequency of coronary artery disease, and a drop in the cost of post-operative cardiac care.

Regional Analysis

North America is the Largest Revenue Holder in the Global Market

Based on region, the global bioabsorbable stents market share is segmented into North America, Europe, Asia-Pacific, and LAMEA.

North America is anticipated to hold the largest market share of USD 153 million by 2030 at a CAGR of 5.7% during the forecast period. Developments in technology and research in North America for bioabsorbable stents and an increase in the proportion of elderly patients with coronary artery disease and pulmonary disease will increase the market for bioabsorbable stents in the years to come. US has the primary market in this region, with revenue of USD 78 million in 2021.

Asia-Pacific is the second-largest contributor to the bioabsorbable stents market because of an increase in the number of people leading sedentary lifestyles, an increase in the prevalence of coronary artery disease, and progress made in the healthcare industry. Asia-Pacific is anticipated to be worth USD 120 million by 2030 at a CAGR of 6.7% during the forecast period. Compared to other countries, China is the most significant contributor to the market, valued at USD 30 million in 2021. Japan and India are growing their market gradually with market revenue of USD 21 million and USD 13 million, respectively, in 2021.

The bioabsorbable stents market in Europe is expected to witness steady growth, with a value of USD 40 million in 2021. The growing incidence of coronary artery disease and peripheral vascular disease, as well as the adoption of unhealthy lifestyle choices, the increase in the geriatric population, the increase in the number of approvals for bioabsorbable stents, the presence of advanced healthcare infrastructure, and the surge in the number of approvals for bioabsorbable stents, are all major factors driving the market forward. Germany and France have more market revenue compared to UK and Italy. The market revenue of Germany and France were valued at USD 14 million and USD 11 million, respectively, in 2021.

LAMEA has the lowest market. In 2021, the market revenue was valued at USD 18 million, with Brazil being their major contributor. Firms' extensive Research and development spending resulted in technological breakthroughs, which boosted the multi-functionality, simplicity of use, and scalability of bioabsorbable stents, resulting in market expansion.

Recent Developments

• April 2021- MicroPort launched the Castor Branched Stent-Graft system in Italy, used for aortic arch repair by minimally invasive treatment.
• March 2021- B Braun collaborated with Infrared to accelerate the clinical trial of SeQurnt Pleases Rex and utilize both its resources for clinical expertise and financial resources.
• March 2021- Elixir Medical announced the INFINITY SWEDEHEART randomized controlled trial (RCT) of the DynamX Coronary Bioadaptor system, the first coronary artery implant to adopt vessel physiology.
• September 2020- To increase its product portfolio, Terumo launched the TREO abdominal stent graft system to treat a patient suffering from abdominal aortic aneurysms.
• June 2020- BIOTRONIK was awarded a group purchasing contract from Vizient to enhance and access biotronik vascular intervention solutions like bare-metal stents, which increases its business segments.

Bioabsorbable Stents Market Segmentation

By Biomaterial

• Polymeric Stents
• Metallic Stents

By Application

• Coronary Artery Disease
• Peripheral Artery Disease

By End-User

• Hospitals
• Cardiac Centers

By Regions

• North America
• Europe
• Asia-Pacific
• LAMEA