September 2025 – Zai Lab Receives Hong Kong Approval for TIVDAK® in Recurrent or Metastatic Cervical CancerZai Lab Limited announced that the Hong Kong Department of Health approved TIVDAK® (tisotumab vedotin-tftv) for adults with recurrent or metastatic cervical cancer whose disease progressed after chemotherapy. The approval expanded access to antibody-drug conjugate (ADC) therapy in the Greater China region.
May 2025 – Adcentrx Therapeutics Receives FDA Fast Track Designation for Cervical Cancer ADC CandidateAdcentrx Therapeutics received U.S. FDA Fast Track designation for ADRX-0706, a Nectin-4 antibody-drug conjugate (ADC) being evaluated for patients with locally advanced or metastatic squamous cell cervical cancer. The designation supports accelerated development of targeted therapies addressing unmet needs in advanced cervical cancer treatment.
March 2025 – Genmab and Pfizer’s TIVDAK® Approved in Japan for Advanced Cervical CancerGenmab A/S announced approval of TIVDAK® (tisotumab vedotin) by Japan’s Ministry of Health, Labour and Welfare for advanced or recurrent cervical cancer patients who progressed after chemotherapy. The approval was supported by results from the Phase 3 innovaTV 301 clinical trial, which demonstrated improved overall survival compared with chemotherapy.
March 2025 – European Commission Approves TIVDAK® for Previously Treated Recurrent or Metastatic Cervical CancerGenmab A/S and Pfizer Inc. received European Commission marketing authorization for TIVDAK® as a monotherapy treatment for adult patients with recurrent or metastatic cervical cancer following systemic therapy. The approval expanded availability of the ADC therapy across European markets.