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CRISPR-Cas9 Gene Editing Technologies Market

CRISPR-Cas9 Gene Editing Technologies Market Size, Share & Trends Analysis Report By Product and Service (Reagents and Consumables, Software and Systems, Services), By Technology (CRISPR, TALEN, ZFN, ANTISENSE, Other technologies), By Applications (Cell Line Engineering, Genetic Engineering, Drug Discovery and Development, Other Applications), By End-User (Pharmaceutical and Biotechnology Companies , Academic and Research Institutes) and By Region(North America, Europe, APAC, Middle East and Africa, LATAM) Forecasts, 2024-2032

Report Code: SRHI215DR
Study Period 2020-2032 CAGR 14.6%
Historical Period 2020-2022 Forecast Period 2024-2032
Base Year 2023 Base Year Market Size USD 2.876 billion
Forecast Year 2032 Forecast Year Market Size USD 9.936 billion
Largest Market North America Fastest Growing Market Europe
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Market Overview

The global CRISPR-Cas9 gene editing market size was valued at USD 2.876 billion in 2023. It is expected to reach USD 9.936 billion by 2032, growing at a CAGR of 14.6% over the forecast period (2024-32). The global CRISPR-Cas9 gene editing technologies market is primarily driven by factors such as increasing investment in gene therapy research and development, growing demand for personalized medicine, and expanding applications of CRISPR-Cas9 in drug discovery and functional genomics. Moreover, advancements in CRISPR-Cas9 technology, such as improved efficiency, specificity, and scalability, are fueling market growth.


  • North America is the highest shareholder in the global market

Market Overview

CRISPR-Cas9 stands as a groundbreaking gene editing technology, facilitating precise and efficient modifications in the DNA of living cells. This innovative tool finds diverse applications across multiple domains, including biomedical research, gene therapy, agriculture, industrial biotechnology, and human reproduction. Within the realm of biomedical research, CRISPR-Cas9 proves instrumental in the creation of animal models for human diseases. In the context of gene therapy, it enables the correction or insertion of genes in individuals with genetic disorders.

Moreover, its utility extends to enhancing crop traits, engineering microorganisms for biofuel, chemical, and pharmaceutical production, investigating gene function and regulation, and editing human embryos for reproductive purposes. The profound implications of CRISPR-Cas9 underscore its potential to revolutionize scientific and medical landscapes, societal norms, and ethical considerations.

Market Dynamics

Global CRISPR-Cas9 Gene Editing Technologies Market Drivers

Growing Demand for Innovative Treatments

The escalating prevalence of genetic diseases and intricate medical conditions has generated a growing demand for innovative therapies capable of targeting the underlying causes of these ailments. Within the CRISPR-Cas9 gene editing technology market, this technology demonstrates substantial promise for advancing gene therapies tailored to address diverse conditions, including but not limited to cystic fibrosis, sickle cell anemia, and cancer. CRISPR-Cas9 is positioned as a pivotal player in pursuing therapeutic breakthroughs, offering the potential to reshape the landscape of genetic medicine by precisely addressing the genetic origins of various disorders.

For Instance, the National Institution of Health (NIH) supports research on CRISPR Cas9 Gene therapy for various diseases, such as cystic fibrosis, sickle cell disease, and cancer. The NIH has funded several clinical trials using CRISPR-Cas9 to modify genes in patients' cells and test their safety and efficacy. The NIH also provides resources and guidance for researchers and clinicians interested in developing and applying CRISPR-Cas9 gene therapy. In summary, NIH support catalyzes the market growth of CRISPR-Cas9 gene editing technologies by driving scientific advancements, validating its therapeutic potential, ensuring safety and efficacy, and providing essential resources and guidance to the research community.

Global CRISPR-Cas9 Gene Editing Technologies Market Restraint

Technical Challenges and Effective/Safe Delivery System

A major obstacle confronting the worldwide market for CRISPR-Cas9 gene editing technologies is the multitude of technical difficulties linked to guaranteeing accurate and secure genome editing. The main concern with these difficulties is the possibility of off-target consequences, which arise when accidental modifications occur in parts of the genome other than the intended target. The incidence of off-target effects presents serious safety issues, requiring continued study to improve the specificity and precision of CRISPR-Cas9 technology.

Another significant barrier to industry expansion for CRISPR-Cas9 tools is the absence of reliable and secure delivery methods. Successful genome editing requires the effective transport of CRISPR-Cas9 components, such as Cas9 proteins and guide RNAs, into target cells. Nevertheless, there are several drawbacks to the current delivery strategies, including poor efficacy, side effects, and possible toxicity or immunogenicity.

Global CRISPR-Cas9 Gene Editing Technologies Market Opportunities

Expansion of Pipeline for Gene Therapy

The growing number of gene therapy candidates undergoing clinical trials with CRISPR-Cas9 opens up substantial opportunities for progressing in treating a wide range of diseases. These trials signify a promising avenue for developing innovative therapies that leverage the precision and efficiency of CRISPR-Cas9 gene editing technology. This surge in clinical trials reflects the enthusiasm within the scientific and medical communities to harness the capabilities of CRISPR-Cas9 for targeted and effective interventions, offering new hope for improved treatments and outcomes in various health conditions.

For instance, the US National Institutes of Health (NIH) maintains a database of clinical trials involving gene therapy, including those using CRISPR-Cas9. According to the NIH, there are currently more than 100 active or recruiting gene therapy trials using CRISPR-Cas9 for various diseases, such as cancer, blood disorders, eye diseases, and infectious diseases. This indicates a growing interest and investment in CRISPR-Cas9 as a potential gene therapy tool. It enhances visibility, fosters investor confidence, showcases diverse applications, and contributes to the scientific validation of CRISPR-Cas9, collectively driving the market forward.

Regional Analysis

Based on region, the global CRISPR-Cas9 gene editing technology market is bifurcated into North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa. 

North America Dominates the Global Market

North America is the most significant global CRISPR-Cas9 gene editing technology market shareholder and is expected to expand substantially during the forecast period. In the US, venture capitalists, governmental organizations, and private companies have made large financial and investment contributions in the gene editing field. North America has a strong research and development base, with prestigious universities and research institutes like Harvard, MIT, and Stanford that foster innovation and discovery in CRISPR technology. These institutions attract top researchers and contribute significantly to advancements in the field. North America also has a vibrant ecosystem of biotechnology companies heavily invested in CRISPR research and development. These companies translate scientific discoveries into practical applications, propelling the market forward.

Moreover, North America has supportive government policies facilitating CRISPR research and development. Government agencies like the NIH in the US provide significant funding for CRISPR research, fostering innovation and accelerating breakthroughs. This enables researchers to pursue promising avenues and develop novel applications. Additionally, North America has clear and established regulatory frameworks that provide a pathway for clinical trials, giving companies and investors confidence in the market's stability and predictability. This fosters a more favorable research and development environment than regions with unclear or underdeveloped regulatory frameworks. Therefore, strong academic and commercial infrastructure and supportive government policies have positioned North America as the global leader in the CRISPR-Cas9 gene editing technology market.

Europe is a major player in the CRISPR-Cas9 gene editing market, with significant growth potential. A growing number of collaborations between academic institutions and industry players are fostering knowledge exchange and accelerating research progress. This synergy between academia and industry can lead to faster development and commercialization of CRISPR-based therapies. European governments actively promote research and development through increased funding initiatives. This financial backing fuels innovation and positions Europe as a significant contributor to the field's advancement. While Europe is not the undisputed leader, it is a strong contender in the CRISPR-Cas9 gene editing market due to its supportive and innovative environment.

Report Scope

Report Metric Details
By Product and Service
  1. Reagents and Consumables
  2. Software and Systems
  3. Services
By Technology
  2. TALEN
  3. ZFN
  5. Other technologies
By Applications
  1. Cell Line Engineering
  2. Genetic Engineering
  3. Drug Discovery and Development
  4. Other Applications
By End-User
  1. Pharmaceutical and Biotechnology Companies 
  2. Academic and Research Institutes
Company Profiles Merck KGaA Thermo Fisher Scientific, Inc. GenScript Agilent Technologies PerkinElmer Lonza Tecan Life Sciences Sangamo Therapeutics Editas Medicine CRISPR Therapeutics AG Precision Biosciences Cellectis S.A. Intellia Therapeutics Bluebird Bio, Inc. Regeneron Pharmaceuticals AMSBIO Creative Biogene Synthego Corporation Beam Therapeutics Inc. Caribou Biosciences, Inc. OriGene Technologies New England Biolabs Inscripta Mammoth Biosciences
Geographies Covered
North America U.S. Canada
Europe U.K. Germany France Spain Italy Russia Nordic Benelux Rest of Europe
APAC China Korea Japan India Australia Singapore Taiwan South East Asia Rest of Asia-Pacific
Middle East and Africa UAE Turkey Saudi Arabia South Africa Egypt Nigeria Rest of MEA
LATAM Brazil Mexico Argentina Chile Colombia Rest of LATAM
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, Environment & Regulatory Landscape and Trends
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Segmental Analysis

The global CRISPR-Cas9 gene editing technology market is bifurcated into products and services, technology, applications, and end-users.

Based on products and services, the global CRISPR-Cas9 gene editing technology market is segmented into reagents and consumables, software and systems, and services.

Reagents and consumables are in a dominating position among the product and service categories of the CRISPR-Cas9 gene editing technology market due to their widespread and frequent use for a variety of applications. CRISPR-Cas9 experiments and diagnostics require the use of products such as library preparation kits, purification kits, target enrichment kits, plates, chips, and tubes throughout the workflow. These products enable the preparation, isolation, enrichment, and analysis of DNA or RNA molecules for gene editing. 

Moreover, CRISPR-Cas9 technology has a broad range of applications in different fields, like gene therapy development, disease modeling, and agricultural biotechnology. Each field requires specific reagents and consumables for different process steps, such as vector construction, cell culture, and disease-causing mutation studies. Therefore, the high frequency and diversity of use of reagents and consumables drive a consistent and significant demand for these products in the CRISPR-Cas9 gene editing technology market.

Based on technology, the global CRISPR-Cas9 gene editing technology market is segmented into TALEN, CRISPR, Antisense, ZFN, and other applications.

CRISPR is the most popular gene editing tool available since it is very accurate, versatile, and easy to use. Unlike other methods, CRISPR is straightforward to build and utilize because it uses a guide RNA molecule to guide the Cas9 enzyme to the desired region in the genome. CRISPR can also perform various functions, such as editing, regulating, or correcting genes and studying their role in an organism. This makes it a versatile tool for various fields and applications. Moreover, CRISPR has a high success rate and accuracy in editing the target cells, minimizing the risk of unwanted changes in the genome. These features make CRISPR a reliable and effective technology for gene editing.

Based on application, the global CRISPR-Cas9 Gene editing technology market is segmented into cell line engineering, genetic engineering, drug discovery and development, and other applications.

The field of CRISPR-Cas9 applications includes cell line engineering, a crucial component that transforms drug development and biological research. Scientists can more easily create customized models for researching diseases and assessing possible treatments by utilizing the variety and precision of CRISPR-Cas9 technology to precisely alter and improve cell lines. With the use of this cutting-edge technique, scientists can precisely modify important biological pathways or imitate mutations linked to disease in cell lines. With unmatched specificity and efficiency, these modified cell lines are useful resources for understanding the mechanisms underlying diseases, identifying potential drugs, and assessing the effectiveness of treatments.

Based on end-users, the global CRISPR-Cas9 gene editing technology market is segmented into pharmaceutical and biotechnology companies and academic and research institutes.

Innovative gene therapies for a range of crippling illnesses, such as cancer, cystic fibrosis, and sickle cell anemia, are being developed by pharmaceutical and biotechnology corporations, who are at the forefront of this effort. CRISPR-Cas9 proves to be a breakthrough tool in this endeavor, providing unmatched precision and potency in genome editing. The emerging paradigm of personalized medicine is well aligned with CRISPR's ability to precisely modify genes on a patient-specific basis. Pharmaceutical companies hope to change the therapeutic landscape and usher in a new era of targeted and effective interventions by customizing therapies based on each patient's genetic profile.

Market Size By Product and Service

Recent Developments

  • February 2023- GenScrip(China) unveiled plans to expand its Singapore facility, focusing on enhancing its gene synthesis services. This strategic move represents a substantial expansion of GenScript's advanced gene-synthesis capabilities. The primary objective of this expansion is to cater to the increasing demand for premium gene synthesis services, particularly in the field of novel vaccine and therapeutics development within the life sciences sector. This expansion of CRISPR-Cas9 Editing technologies supports cutting-edge research and development initiatives, contributing to life sciences and biotechnology advancements.
  • December 2023- The International Service for Acquisition Agri-biotech Applications (ISAAA), a non-profit organization promoting biotechnology benefits, approved Casgevy, the first gene therapy using CRISPR-Cas9 to treat sickle cell disease. It has the potential of CRISPR-Cas9 as a novel and innovative treatment for sickle cell disease, a rare and life-threatening blood disorder. It also showcases the first FDA approval of a CRISPR-based therapy, which could pave the way for more applications and approvals in the future. This could boost the demand and growth of the CRISPR-Cas9 market and public awareness and acceptance of the technology.

Top Key Players

Merck KGaA Thermo Fisher Scientific, Inc. GenScript Agilent Technologies PerkinElmer Lonza Tecan Life Sciences Sangamo Therapeutics Editas Medicine CRISPR Therapeutics AG Precision Biosciences Cellectis S.A. Intellia Therapeutics Bluebird Bio, Inc. Regeneron Pharmaceuticals AMSBIO Creative Biogene Synthego Corporation Beam Therapeutics Inc. Caribou Biosciences, Inc. OriGene Technologies New England Biolabs Inscripta Mammoth Biosciences Others

Frequently Asked Questions (FAQs)

How big is the CRISPR-Cas9 gene editing technologies market?
The global CRISPR-Cas9 gene editing technologies market size was valued at USD 2.876 billion in 2023. It is expected to reach USD 9.936 billion by 2032, growing at a CAGR of 14.6% over the forecast period (2024-32).
Europe region has the highest growth rate in the CRISPR-Cas9 gene editing technologies market.
Growing demand for innovative treatments is the major growth factor of the CRISPR-Cas9 gene editing technologies market.
Reagents and consumables segment is the leading segment for the market during forecast period.
The key players in the global CRISPR-Cas9 gene editing technologies market include Merck KGaA, Thermo Fisher Scientific, Inc., GenScript, Agilent Technologies, PerkinElmer, Lonza, Tecan Life Sciences, Sangamo Therapeutics, Editas Medicine, CRISPR Therapeutics AG, Precision Biosciences, Cellectis S.A., Intellia Therapeutics, Bluebird Bio, Inc., Regeneron Pharmaceuticals, AMSBIO, Creative Biogene, Synthego Corporation, Beam Therapeutics Inc., Caribou Biosciences, Inc., OriGene Technologies, New England Biolabs, Inscripta, Mammoth Biosciences.

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