Diabetic Neuropathy Market: Information by Disorder Type (Peripheral Neuropathy, Focal Neuropathy, Autonomic Neuropathy), Treatment (Drugs, Others), and Region-Forecast till 2029

Mar 23, 2020   Diabetic neuropathy is a type of nerve damage that can occur due to prolonged uncontrolled high blood sugar levels which most often resonates with clinical diabetic conditions. Scientifically, high blood sugar (glucose) can injure nerves throughout the body and often lead to clinical manifestations of several symptoms. Diabetic neuropathy most often damages nerves in the legs and feet regions. Depending on the affected nerves, diabetic neuropathy symptoms can range from pain and numbness in the ...
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Report Description

Diabetic neuropathy is a type of nerve damage that can occur due to prolonged uncontrolled high blood sugar levels which most often resonates with clinical diabetic conditions. Scientifically, high blood sugar (glucose) can injure nerves throughout the body and often lead to clinical manifestations of several symptoms. Diabetic neuropathy most often damages nerves in the legs and feet regions. Depending on the affected nerves, diabetic neuropathy symptoms can range from pain and numbness in the legs and feet to problems with the digestive system, urinary tract, blood vessels, and heart. The diabetic Neuropathy Market consists of drugs, treatment regimes, monitoring devices, and medications that are aimed to address the symptomatic effects of the disease like pain and numbness.

Diabetic-Neuropathy-Market-Updated

The global diabetic neuropathy market was valued at USD 85,011.7 million in 2019 and is expected to grow at a 7.11 % CAGR during the forecast period.

Rapidly Increasing Chronic Diabetic Patients Globally has been Driving the Global Market

Diabetes is one of the predominant diseases with substantial adverse consequences on human health. These chronic lifestyle diseases are extensively spread across all regions and traced in individuals from all socioeconomic statuses. As per reports from National Diabetes Statistics Report in 2020, by the Centers for Disease Control and Prevention (CDC), it is found that 34.2 million U.S. individuals (10.5% of the U.S. population) were clinically diagnosed with Diabetes in 2018.

Diabetic-Neuropathy-Market-Growth-Updated

Table 1: Estimated Number of Adults Aged 18 Years or Older With Diagnosed Diabetes, Undiagnosed Diabetes, and Total Diabetes, the United States, 2018

Characteristics

Diagnosed diabetes cases

(No. in Millions) (95% CI)

Undiagnosed diabetes cases

(No. in Millions) (95% CI)

Total cases

(No. in Millions) (95% CI)

Total

26.8

7.3

34.1

Age in Years

18-44

3.6

1.4

4.9

45-64

11.7

3.1

14.8

>65

11.5

2.9

14.3

Sex 

Male

14.0

3.9

17.9

Female

12.8

3.4

16.2

Source- National Diabetes Statistics Report, U.S. Census Bureau 2018

Further, researchers and scientists across the globe have shown scientific evidence that links diabetes with its associated neuropathy. For instance, as Mayo Clinic reported, approximations suggest that symptoms and complications of diabetic neuropathy may be traced in as many as 50% of people who have diabetes. Further, as published in current diabetes reports, depending on factors, such as age, duration of imbalanced blood sugar, glucose regulation, among other factors, the prevalence of peripheral neuropathy in adults with diabetes is estimated to be between 6% and 51%. Therefore, attributed to such high risks and health issues associated with uncontrolled diabetes that leads to neuropathy, the market products are in demand.

Growing Awareness among People and Increasing Dependence on Diabetes Control Measure to Bolster Market Growth

With the rising prevalence of chronic diabetes across all regions, there is a massive patient pool globally. Thus, gradually, people worldwide have gained awareness regarding the same, irrespective of whether someone they know has suffered from the same or not. Further, numerous initiatives have been taken to make people aware of such diabetic complications, which is promoting the market as people seek treatment and care services. Also helping the market development is the growing awareness about health care facilities and preventive treatment that are continually growing to accommodate more services.

Many government initiates have been launched to address the motive of growing public awareness. For instance, the month of November is declared as Diabetes Awareness Month. Further, November 14th is celebrated as World Diabetes Day, all of which are intended to help raise awareness for Type 1 and Type 2 diabetes and effective treatment and preventive measures. Additionally, several government organizations like the National Institute of Neurological Disorders and Stroke (NINDS), under the U.S. National Institute of Health (NIH), the World Health Organization (WHO), Indian Medical Research Council (ICMR), among others, have conducted many types of research as well as awareness programs to spread awareness regarding such complications. For instance, NINDS conducts and supports research on diabetic neuropathy to increase understanding of the disorder and find newer ways to prevent and cure it.

Diabetic Neuropathy Market: Segmentation

Peripheral Neuropathy Dominates the Global Market in Terms of Revenue, by Disorder Type

The peripheral neuropathy segment dominates the global market valued at 66,372.5 million USD in 2019 and is expected to keep dominating the market with market revenue of 92,376.3 million USD in 2025, growing at 7.44% CAGR. The high rate of incidence of peripheral neuropathy is expected to further boost the sub-segmental products. For instance, according to the National Institute of Neurological Disorders and Strokes, there are more than 20 million people in the United States who have been estimated to have developed some form of peripheral neuropathy. Thus, the naturally peripheral diabetic neuropathy segment dominates the market share. While there are no permanent treatments that have been developed which could reverse the diseased condition, medications and therapy-based means are available that is intended to keep the blood glucose levels in range to prevent the progression of peripheral neuropathy. For instance, the two FDA approved medications for symptomatic effects of diabetic peripheral neuropathy are Cymbalta (Elli Lilly and Company) and Lyrica (Pfizer Inc.).

Drugs Segment is the Largest Contributor in Terms of Revenue, by Treatment Type

The drug segment by treatment dominates the global market, valued at 61,154.5 million USD in 2019 and is estimated at 84,133.9 million USD in 2025. Further, the drug segment of the market is one of the fastest-growing segments of the market growing at a 7.21% CAGR, owing to multiple factors. New drug approvals due to large-scale product development, growing demand for prescription therapeutics for diabetes and associated complications, and a strong drug pipeline within the key players are few such factors that are fueling the segmental growth.

Additionally, with the rising prevalence of diabetic neuropathy, owing to the increasing diabetic population across the globe, several market players have channelized capital, focusing on the development of therapeutic drugs to treat the disease.  The growing segment of biosimilar industries due to the patent expiry of several generic drugs has further boosted the segment as more and more market players develop drugs to try and fulfill the unmet demands.

Regional Overview

North-America-Lead-Diabetic-Neuropathy-Market-Growth-Updated

North America Regional Market Dominates the Global Market in Terms of Revenue

The American regional market was valued at 34,328.9 million USD growing at a 7.15% CAGR. Market dominance can be attributed to a high prevalence of diabetes in the region. Due to the large pool of patients and wider acceptance of advanced technologies, and developed countries like the United States and Canada, the region held the major chunks of the market. For instance, according to reports published by the American Diabetes Association (ADA), in 2018, 34.2 million Americans that attribute to 10.5% of the population were estimated to have either type of Diabetes.

Further, dedicated research activities have established the association of neuropathy with diabetes and have concluded that the majority of the people with clinically diagnosed diabetic conditions are at significant risk of suffering from neuropathy. Further, an American study published in the neurology journal estimates that 47% of patients with diabetes have or will be diagnosed with some peripheral neuropathy during the lifetime. This has fueled the diabetic neuropathy market for treatment and monitoring devices as well as medications to regulate and stabilize high blood sugar. 

Further, huge capital investments in the region have significantly boosted the market. For instance, according to the ADA, 1 in every 4 healthcare dollars was spent on treating people with diabetes in 2017, and the direct medical costs and indirect expenditures attributable to diabetes in the United States were an estimated USD 327 billion.

APAC Regional Market Has Shown Market Potential and Is Expected to Witness Fastest Growth Rate

Asia-Pacific is the fastest-growing market with an 8.10% CAGR. Asia-Pacific has a substantial market potential for the diabetic neuropathy market due to the significant prevalence rate in the region. For instance, a study by Pan et al. estimated that in Beijing, China, peripheral neuropathy had prevalence rates of 21.92% and 35.34% in patients with type 1 and type 2 diabetes, respectively. This can be attributed to the growing diabetic population as well as the rising geriatric population in the region. According to the International Diabetes Federation, around 60% of diabetic patients live in Asia. Further, China and India combined have the highest number of patients, owing to the large population in the two countries and the proportion of individuals in the geriatric segment.

With fast economic growth and growing policy measures in Asia-Pacific, the biggest market players are entering the region's untapped market. Also, in Asia-Pacific, the demand for the market is expected to gain substantial momentum due to partnerships between endocrinologists, credentialed diabetes educators, and diabetes prevention stakeholder organizations and market leaders. For instance, in August 2020, Sonnet BioTherapeutics signed a Letter of Intent for licensing of neuropathies asset to new Life Therapeutics. The letter of intent has been executed to negotiate an agreement to license the company’s SON-081 and SON-080 assets, both of which are low-dose Interleukin 6 formulations, for diabetic peripheral neuropathy to New Life Therapeutics of Singapore.

Key Players

  • Abbott
  • Hoffmann-La Roche Ltd.
  • Eli Lilly and Company
  • Johnson & Johnson Services, Inc.
  • GlaxoSmithKline Plc
  • Lupin Pharmaceuticals, Inc.
  • Pfizer Inc.
  • Innovus Pharmaceuticals, Inc
  • Astellas Pharma Inc.
  • Assertio Holdings, Inc.
  • Glenmark Pharmaceutical Limited

Recent Developments

  • On 15 October 2020, Eli Lilly announced a definitive agreement to acquire Disarm Therapeutics, a privately-held biotechnology company that a potent SARM1 inhibitor and is advancing them in preclinical development, intending to deliver breakthrough treatments to patients with peripheral neuropathy and other neurological diseases such as amyotrophic lateral sclerosis (ALS) and multiple sclerosis.
  • On 06 March 2019, Innovus Pharmaceuticals, launched its Diabasens Product in Canada that functions in relieving cutaneous pain associated with diabetic neuropathy. 

Diabetic Neuropathy Market: Segmentation

By Disorder Type

  • Peripheral Neuropathy
  • Autonomic Neuropathy
  • Proximal Neuropathy
  • Focal Neuropathy

By Treatment

  • Drugs
  • Physiotherapy
  • Others

By Region

  • North America
  • Europe
  • Asia-Pacific
  • The Middle East & Africa
  • Central and South America and the Caribbean

Frequently Asked Questions (FAQs)

increasing geriatric population, rising healthcare expenditure, surging research activities, increasing awareness regarding advanced care treatments, and rising incidences of neuropathic pain due to chemotherapy are the key factors expected to drive Diabetic Neuropathy Market during the forecast period.
Drug Segment is expected to be the leading segment in Diabetic Neuropathy Market during the forecast period.
North America is expected to hold the highest market share in Diabetic Neuropathy Market.
Abbott Laboratories, Hoffmann-La Roche Ltd, Eli Lilly and Company, Johnson & Johnson, GlaxoSmithKline Plc, Lupin Limited, Innovus Pharmaceuticals, Depomed, Inc, Astellas Pharma Inc, Pfizer Inc, are the top players in Diabetic Neuropathy Market.
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