Isosorbide Market Size & Outlook, 2025-2033

Isosorbide Market Size

The global isosorbide market size was valued at USD 659.7 million in 2024 and is expected to grow from USD 707.3 million in 2025 to reach USD 1,260.1 million by 2033, growing at a CAGR of 7.08% during the forecast period (2025-2033).

The global isosorbide market is experiencing robust growth, driven by increasing demand for sustainable and bio-based alternatives to petrochemical-derived products. Isosorbide, a diol derived from sorbitol, is gaining traction due to its biodegradability, low toxicity, and versatility in applications such as polymers, resins, and pharmaceuticals. The push towards environmentally friendly materials, coupled with stringent regulations on carbon emissions, is propelling the adoption of isosorbide in various industries. Notably, the Asia-Pacific region is emerging as a significant market, with countries like China and India investing in green technologies and sustainable manufacturing practices. However, challenges such as high production costs and competition from established petrochemical products may hinder market growth. Nonetheless, ongoing research and development efforts to improve production efficiency and expand application areas are expected to create new opportunities for market expansion.

Isosorbide Market Trend

Rising Demand in Pharmaceuticals

The pharmaceutical industry's growing interest in isosorbide derivatives, such as isosorbide mononitrate and isosorbide dinitrate, is a significant driver of market growth. Due to their vasodilatory properties, these compounds are widely used in treating cardiovascular diseases, including angina pectoris and heart failure. The increasing prevalence of cardiovascular conditions globally, attributed to ageing populations and lifestyle changes, is fueling the demand for these medications.

Moreover, the trend towards developing sustained-release formulations to improve patient compliance is further augmenting the use of isosorbide derivatives. Recent technological advancements have led to the development of extended-release formulations and transdermal patches, enhancing patient adherence. Additionally, the pharmaceutical industry is experiencing a shift towards sustainable practices, with isosorbide serving as a bio-based excipient in drug formulations. This growing pharmaceutical demand, coupled with innovations in drug delivery systems, is expected to contribute significantly to the overall expansion of the isosorbide market.

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Isosorbide Market Driver

Shift towards Bio-Based Polymers

The isosorbide market is experiencing a significant shift towards bio-based polymers, particularly in the packaging industry. Isosorbide is increasingly utilised as a monomer in producing polyethene isosorbide terephthalate (PEIT), a bio-based alternative to polyethene terephthalate (PET). PEIT offers superior thermal stability and mechanical properties, making it suitable for high-performance applications. The growing consumer awareness regarding environmental sustainability and regulatory pressures to reduce carbon footprints drives the demand for bio-based polymers. The European Union's directive on single-use plastics encourages manufacturers to adopt sustainable materials, boosting the market.

• For instance, BASF announced plans in June 2024 to expand its line of bio-based products, including industrial-grade isosorbide, as part of its carbon-reduction initiatives.

These advancements, coupled with ongoing research and development in polymerisation technologies, enhance the feasibility of large-scale PEIT production, indicating a promising future for isosorbide-based polymers.

Market Restraining Factors

High Production Costs

Despite isosorbide's favourable properties and applications, high production costs remain a significant restraint to market growth. The manufacturing process of isosorbide involves multiple steps, including the hydrogenation of glucose to sorbitol and subsequent dehydration to isosorbide, which are energy-intensive and require specialised equipment. Additionally, the cost of raw materials and catalysts further adds to the overall production expenses. These high costs make isosorbide-based products less competitive than their petrochemical counterparts, limiting their adoption, especially in price-sensitive markets. Efforts are underway to develop more cost-effective and efficient production methods, such as enzymatic processes and continuous flow reactors, which could 9reduce manufacturing expenses.

However, until these technologies are commercially viable, high production costs will continue to challenge the widespread adoption of isosorbide. Furthermore, the availability of sorbitol, the primary feedstock for isosorbide production, is subject to agricultural factors, which can impact production and pricing.

Market Opportunity

Expansion in the Asia-Pacific Region

The Asia-Pacific region presents significant growth opportunities for the isosorbide market, driven by rapid industrialisation, urbanisation, and increasing environmental awareness. Countries like China, India, and Japan invest heavily in sustainable technologies and green chemistry initiatives, creating a favourable environment for bio-based chemicals like isosorbide.

• For instance, the Indian government's "Make in India" campaign, which focuses on sustainable development, encourages the establishment of bio-refineries and the adoption of renewable chemicals. Similarly, China's commitment to reducing carbon emissions and promoting circular economy principles boosts the demand for bio-based materials.

Moreover, the region's large consumer base and growing middle-class population drive the demand for eco-friendly products, including packaging materials and personal care items made from isosorbide. Collaborations between local manufacturers and international companies also facilitate technology transfer and capacity building, further enhancing the market potential in the Asia-Pacific region.

Regional Insights

Asia-Pacific dominates the isosorbide market, with countries like China, India, and Japan leading the charge. This dominance is attributed to the easy availability of raw materials, cost-effective labour, and the expansion of end-use industries such as pharmaceuticals, personal care, nutraceuticals, and cosmetics. The region's prominent players and large polymer manufacturers further bolster its leading position. Additionally, government regulations aimed at reducing VOC content in paints and coatings and adopting bio-based materials in the automotive industry have driven the demand for isosorbide. The region's rapid industrialisation, increasing environmental awareness, and supportive government policies are key drivers. The region's large population and expanding middle class further fuel demand for sustainable products, positioning Asia-Pacific as a critical market for isosorbide.

China Isosorbide Market Trends

• China's isosorbide industry is expanding rapidly, driven by the government's focus on sustainable development and environmental protection. Investments in green chemistry and bio-based materials encourage the adoption of isosorbide in various industries. The country's large manufacturing base and growing consumer awareness further fuel market growth. This robust growth trajectory underscores China's significant role in the global isosorbide market.
• India is emerging as a significant market for isosorbide, supported by government initiatives promoting green chemistry and sustainable materials. The country's growing packaging and textile industries are adopting isosorbide-based products to meet environmental standards. Investments in research and development are also contributing to the market's expansion. India's focus on enhancing its healthcare infrastructure and increasing pharmaceutical exports contributes to the growth of its biopharmaceutical logistics market. The nation's commitment to sustainable development positions it as a key player in the market.

North America Isosorbide Market Trends

North America is projected to be the fastest-growing region in the isosorbide market. The region's growth is fueled by rigorous environmental regulations and a high adoption rate of sustainable materials, particularly in sectors like pharmaceuticals and bioplastics. The presence of major pharmaceutical companies and a shift towards eco-friendly materials support this growth. Additionally, collaborations between industry and academia foster innovation in isosorbide applications, particularly in developing advanced polymers and pharmaceuticals.

• The United States is pivotal in the global isosorbide market, driven by its robust research infrastructure and commitment to sustainable materials. The nation's focus on green chemistry has led to significant investments in bio-based polymers, particularly in sectors like automotive, packaging, and pharmaceuticals. The U.S. government's support through favourable policies and subsidies encourages manufacturers to adopt eco-friendly raw materials. Additionally, the pharmaceutical industry's growing interest in isosorbide derivatives, such as isosorbide mononitrate and isosorbide dinitrate, is fueling market growth. Collaborations between academia and industry further accelerate innovation, positioning the U.S. as a leader in isosorbide application development.
• Canada's isosorbide market is experiencing steady growth, bolstered by government initiatives promoting sustainable development and the use of bio-based materials. The country's commitment to reducing carbon emissions and fostering a circular economy encourages industries to adopt renewable resources like isosorbide. Collaborations between research institutions and industry players are driving innovation, leading to the development of advanced isosorbide applications. This growth underscores Canada's strategic position in the bio-based materials sector.

Europe Isosorbide Market Trends

Europe is experiencing significant growth in the isosorbide market, driven by strong governmental support for bio-based products and stringent EU sustainability directives. The region sees substantial applications in the personal care and pharmaceutical sectors, influenced by consumer preferences for natural ingredients and sustainable products. Europe's advanced chemical manufacturing capabilities and research & development initiatives further bolster market dynamics. The region's commitment to establishing a bio-based sector and implementing numerous plans and policies to achieve long-term economic growth is expected to drive isosorbide demand. The European Union's policies promote the circular economy and reduction of carbon emissions, encouraging the adoption of isosorbide in various industries. Furthermore, collaborations between governments and the private sector are leading to the development of innovative applications for isosorbide, enhancing its market presence in the region.

• The United Kingdom is witnessing a notable increase in the adoption of isosorbide, particularly in the packaging and personal care sectors. Government policies to reduce plastic waste and promote sustainable materials are key drivers of this trend. Research and development activities focusing on bio-based polymers enhance the market's growth prospects. The UK's commitment to sustainability is evident in initiatives like the USABLE PACKAGING project, which aims to establish a new value chain for bioplastics based on low-cost and widely available feedstock. Such endeavours position the UK as a significant contributor to the market.
• Germany is a leader in the European isosorbide market, strongly emphasising research and innovation. The country's commitment to sustainability and stringent environmental regulations promotes the use of bio-based materials. Collaborations between academia and industry are fostering the development of advanced isosorbide applications, particularly in the automotive and packaging sectors. Germany's advanced chemical manufacturing capabilities and research & development initiatives further bolster market dynamics. The nation's proactive approach to sustainable development solidifies its position in the market for isosorbide.

Product Type Insights

Oil-based isosorbide continues to dominate the global market due to its cost-effectiveness and established production infrastructure. The widespread availability of oil and economies of scale make oil-based isosorbide more affordable than its bio-based counterparts. Additionally, the consistent quality and performance characteristics of oil-based isosorbide are vital for applications, especially in the pharmaceutical industry, where stringent quality and safety standards are mandatory. The well-controlled production processes ensure that the isosorbide meets these rigorous standards, further solidifying its dominance in the market. However, the growing emphasis on sustainability and environmental concerns gradually shifts towards bio-based isosorbide, prompting manufacturers to invest in research and development for more sustainable production methods.

Application Insights

Polyethylene isosorbide terephthalate (PEIT) dominates the application segment, driven by its superior thermal resistance and mechanical strength. As a bio-based polymer, PEIT is a sustainable alternative to traditional PET, and it is used extensively in packaging applications such as hot-fill containers, jars, and bottles. The growing demand for bio-based PET and the increasing significance of bio-refining industries in developing novel bio-based polymers have propelled PEIT's prominence. In 2024, PEIT accounted for over 26.3% of the market share, reflecting its critical role in the transition towards sustainable packaging solutions. Recent advancements in polymerisation technologies have enhanced the feasibility of large-scale PEIT production, indicating a promising future for isosorbide-based polymers.

End-Use Industry Insights

The polymers and resins segment leads the end-use industry, attributed to the escalating demand for bio-based materials in various applications. Isosorbide's integration into the bio-refining industry for developing novel bio-based polymers and resins has been significant. The shift towards sustainable materials in the automotive, packaging, and construction sectors has further amplified the demand for isosorbide in polymers and resins, aligning with global sustainability goals. Additionally, isosorbide's compatibility with other polymers enhances materials' mechanical and optical properties, making it a preferred choice in various applications.

Company Market Share

The global isosorbide market is characterised by several key players focusing on innovation, strategic partnerships, and expansion to strengthen their market position. Companies are investing in research and development to enhance product quality and explore new applications for isosorbide. Collaborations with academic institutions and other industry players are common strategies to drive innovation and market growth.

• Roquette Frères: Roquette Frères is a leading player in the market and is known for its commitment to sustainability and innovation. The company offers a range of isosorbide-based products catering to various industries, including pharmaceuticals, polymers, and personal care. Roquette's strategic focus on research and development has led to the introduction of high-quality, bio-based materials that meet the evolving needs.

List of key players in Isosorbide Market

1. Roquette Frères
2. Mitsubishi Chemical Corporation
3. Archer Daniels Midland Company
4. Novaphene
5. Samyang Biopharmaceuticals Corporation Inc.
6. J&K Scientific Ltd.
7. Jinan Hongbaifeng Industry & Trade Co. Ltd.
8. Par Pharmaceutical
9. Thermo Fisher Scientific
10. Merck KGaA
11. TCI Chemicals
12. ApexBio Technology
13. Oakwood Products Inc.
14. BioCrick Biotech
15. Fintech Industry Limited

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Recent Developments

• January 2024- Roquette achieved the International Sustainability and Carbon Certification (ISCC) PLUS for its POLYSORB® isosorbide, produced in Lestrem, France. This certification underscores Roquette's commitment to sustainable practices in producing plant-based ingredients.