Manual Pipettes Market

Market Overview

The global manual pipettes market was valued at USD 3.02 billion in 2022. It is estimated to reach USD 4.39 billion by 2031, growing at a CAGR of 4.25% during the forecast period (2023–2031). There has been a surge in the incidence of chronic illnesses worldwide, which has led to an increase in clinical diagnostic tests, which is, in turn, driving the global manual pipette market. Moreover, the surging expenditure on healthcare advancements and research and development in emerging economies is expected to create opportunities for market growth as pipettes are extensively used in these fields.

Manual pipettes, sometimes referred to as mechanical pipettes or manual micropipettes, are indispensable laboratory tools utilized for precise measurement and transfer of minute liquid quantities. These instruments find extensive utilization throughout several scientific and medical domains, encompassing molecular biology, biochemistry, chemistry, and clinical laboratory settings. Manual pipettes exhibit variations in size and design. However, they typically encompass a piston-driven mechanism for accurate liquid aspiration and dispensation.

Manual pipettes are specifically engineered to deliver accurate and precise measurements. Accuracy pertains to the degree of proximity between a measured value and the true value, whereas precision concerns the reliability and consistency of measurements. The precision and dependability of results produced with manual pipettes also depend on calibration and maintenance. It is recommended that users adhere to the manufacturer's guidelines for calibration, cleaning, and storage procedures to uphold the optimal performance of the pipette.

Market Dynamics

Global Manual Pipettes Market Drivers

Growing Demand for Clinical Diagnostics

An increase in the prevalence of chronic ailments, including cancer, cardiovascular disease, and diabetes, has resulted in an elevated need for clinical diagnostic tests that facilitate the monitoring, management, and early detection of these conditions. For instance, according to the September 2023 WHO update, chronic disease accounts for 74% of deaths worldwide, equivalent to 41 million people annually.

Additionally, the surging geriatric population further contributes to this burden of chronic disease. For instance, based on research conducted by the National Council on Aging (NCOA), it has been found that around 95% of individuals aged 60 and above are diagnosed with at least one chronic illness, with over 80% experiencing the coexistence of two or more such conditions. Therefore, a growing demand for diagnostic tests in healthcare, including molecular diagnostics and clinical chemistry, requires precise liquid handling tools, contributing to the market growth of manual pipettes.

Global Manual Pipettes Market Restraint

Availability of Alternative Pipette Options

The increasing adoption of laboratory automation has the potential to impede the growth of the manual pipette market. Automated pipetting systems provide increased throughput, precision, and reproducibility, diminishing dependence on manual pipettes in specific applications. Moreover, the COVID-19 pandemic expedited the implementation of automation in many sectors, encompassing laboratory settings. The demand for expeditious and efficient testing procedures may prompt a transition toward automated pipetting technologies.

Furthermore, the increasing adoption of disposable pipettes, which prevents the necessity for frequent cleaning and calibration inherent in manual pipettes, may increase in popularity, influencing the demand for conventional reusable manual pipettes. These factors are predicted to restrict market expansion.

Global Manual Pipettes Market Opportunities

Rising Demand from Emerging Economies

With emerging markets' ongoing investment in healthcare and research infrastructure, the possibility of heightened utilization of manual pipettes exists. For instance, according to ITA, Brazil allocates 9.1% of its gross domestic product (GDP) towards healthcare expenditures. Moreover, the projected government expenditure on healthcare in the Gulf Cooperation Council (GCC) reached nearly USD 30.5 billion in 2021, a significant increase from the previous figure of USD 2.4 billion recorded in 2016. This growth will follow a compound annual growth rate (CAGR) of 6%.

Furthermore, research and development (R&D) is the foundation for the UAE's exponential economic expansion and is a top government priority. For example, the Emirates Research and Development Council was established by the R&D Governance Policy unveiled in 2021 and was one of several recent campaigns and initiatives designed to support R&D in the UAE. Moreover, the Abu Dhabi Government has earmarked AED 4 billion for the advancement of research and development (R&D) inside the region. Thus, the high expenditure in healthcare and research and development in emerging economies is expected to create opportunities for manual pipette market growth as they are integral apparatuses in healthcare and research.

Regional Analysis

Based on region, the global manual pipettes market is bifurcated into North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa.

North America is a highly advanced region owing to the presence of developed nations like the U.S. and Canada. The regional market expansion can be ascribed to the demand from academic institutions and research laboratories, where manual pipettes are extensively utilized for a wide range of studies. Academic institutions in the United States have typically been responsible for conducting approximately 10% to 15% of total U.S. research and development (R&D) and roughly half of all U.S. fundamental research. They incurred USD 83.7 billion in R&D expenditures in 2019. Basic research received funding equivalent to nearly two out of every three dollars allocated to academic R&D, thereby driving the manual pipette market in the North American region. Moreover, promoting enhanced knowledge and educational initiatives on appropriate laboratory methodologies and equipment utilization can facilitate the widespread acceptance and implementation of precise manual pipetting practices.

Additionally, the key players in the region, like Corning Incorporated, Denville Scientific, Thermo Fisher Scientific, and Gilson, are further driving market growth in North America. Moreover, the flourishing prevalence of chronic diseases has increased the demand for diagnostic testing in healthcare settings, such as clinical and research laboratories. For instance, as per CDC, 4 out of 10 adults have two or more chronic diseases, and 6 out of 10 adults have at least one chronic condition in the United States. Similarly, according to NLM, the projected prevalence of at least one chronic disease among those aged 50 years and above is expected to experience a substantial growth of 99.5%, rising from 71.522 million in 2020 to an estimated 142.66 million by the year 2050. Thus, the demand for manual pipettes is increasing in the region.

The Asia-Pacific region is expected to grow at a significant pace. The region has a huge prevalence of chronic illnesses, and with a surge in the geriatric population, the situation worsens. For instance, according to the OECD, it is projected that the proportion of individuals aged 65 years and older will undergo a twofold increase in lower-middle- and low-income nations and territories within the Asia-Pacific region throughout the forthcoming decades, ultimately reaching a level of 13.4% by the year 2050. The proportion of elderly people is predicted to be notably significant in Korea and Hong Kong (China), with over 40% of the population anticipated to be 65 and above by the year 2050. Thus, this aging population increases the demand for diagnostic tests to examine chronic illnesses, which is expected to boost the demand for clinical diagnostics and, ultimately, the manual pipette market.

Furthermore, the nations in the region are spending significantly on R&D, which is expected to drive the manual pipettes market. For instance, in 2000, China's contribution to global research and development (R&D) funding was less than 5 percent. Nevertheless, it is worth noting that China had a substantial rise in its research and development (R&D) expenditure by the year 2020. This increase resulted in China providing more than 24 percent of overall worldwide financing, as the Congressional Research Service (CRS) reported. In addition, China currently holds the position as the second-largest investor in research and development (R&D) among prominent nations, thereby underscoring the nation's aspirations in science and technology. Therefore, this increase in R&D spending increases the research programs conducted in the region, and all the research relating to life sciences encompasses the use of pipette as its vital apparatus, thereby boosting market growth.

Segmental Analysis

The global manual pipettes market is segmented by type and application.

Based on type, the global manual pipettes market is divided into single-channel and multichannel manual pipettes. 

The single-channel pipette is a handheld device that transfers fluids between different containers. The pipette possesses a nozzle at one extremity and a plunger at the opposite end. Squeezing the plunger to initiate vacuum suction will facilitate liquid suction. The pressurized liquid will be released into the receiving container as soon as the timer goes off. Single-channel pipettes are offered in various sizes, encompassing a range of capacities from 0.05 to 100 ml. Typically, these pipettes are composed of either plastic or glass materials.

A manual pipette with multiple channels is a laboratory instrument used to precisely measure and transfer tiny volumes of liquid. In contrast to single-channel pipettes, designed to manipulate one sample at a time, multiple-channel pipettes are specifically constructed to aspirate and dispense liquid in numerous channels concurrently. These pipettes are especially beneficial when working with multi-well plates, such as 384-well or 96-well plates, where liquid management requires efficiency and accuracy.

Additionally, the pipettes exhibit variability in the number of channels, with an average range of eight to twelve. The quantity of channels is determined by the laboratory application's requirements and the design. The use of a multiple-channel manual pipette requires strict adherence to correct pipetting procedures to ensure reliable and accurate results in laboratory studies.

Based on application, the global manual pipette market is segmented into laboratories, hospitals, clinics, and others.

Manual pipettes are of utmost importance in hospitals as they fulfill the essential functions of manipulating, processing, and examining samples. The device is employed to acquire accurate measurements of biological specimens from individuals, including but not limited to blood, urine, and various bodily fluids. This phase is frequently considered crucial in the process of diagnostic testing. In certain instances, it may be necessary to dilute samples to adjust their concentration to a level that falls within the detectable range of an assay.

Additionally, pipettes are crucial in ensuring precise and consistent dilution factors. Automated pipetting technologies are more prevalent in contemporary laboratory settings; however, manual pipettes are indispensable for numerous jobs due to their versatility and cost-efficiency.

Manual pipettes are widely utilized in laboratory settings to conduct various experiments and examinations. Precision is a key characteristic of these devices since they facilitate the transfer of liquids or solutions between containers with minimal or no leakage. One significant advantage of manual pipettes is their versatility in accommodating operations of varying scales, both small and large, in the foreseeable future.

Recent Developments

• October 2023- In its recent 'INTEGRA supports start-ups' competition, INTEGRA Biosciences granted the bioanalytical company DNTOX 31 EVOLVE manual pipettes, GRIPTIPS® pipette tips valued at USD 1,000, and lab accessories. Implementing pipettes will significantly enhance the organization's testing capacity and propel research in this critical domain by streamlining neurotoxicological hazard assessments.
• May 2023- Molecular diagnostics start-up Nanopath was selected as the first-ever Integra supports start-ups competition winner. In recognition of its achievement, the company will receive 30 EVOLVE manual pipettes, which will be instrumental in advancing the development of its innovative technology and facilitating its clinical application.