Nicotinic Acid Market Size & Outlook, 2025-2033

Nicotinic Acid Market Size

The global nicotinic acid market size was valued at USD 331.15 million in 2024 and is anticipated to grow from USD 338.24 million in 2025 to reach USD 400.67 million by 2033, growing at a CAGR of 2.14% during the forecast period (2025–2033). The growth of the market is attributed to rising prevalence of cardiovascular diseases.

One of the major drivers of the global nicotinic acid market is the rising demand for dietary supplements and nutraceuticals. With increasing awareness about preventive healthcare, consumers are turning to vitamins and functional ingredients like nicotinic acid (Vitamin B3) for improved metabolic, neurological, and skin health. This compound is widely used in multivitamin supplements and energy products, driven by the growing popularity of wellness-focused lifestyles.

According to the Council for Responsible Nutrition, over 75% of U.S. adults used dietary supplements in 2023, indicating strong market potential. Additionally, the pharmaceutical industry continues to utilize this compound in therapies for niacin deficiency and lipid disorders. Innovations such as extended-release formulations have improved patient tolerance, thereby enhancing adoption. The convergence of health-conscious behavior, aging populations, and product innovation is significantly contributing to the sustained growth of the global market.

Key Market Indicators

• North America dominated the nicotinic acid industry and accounted for a 33% share in 2024.
• Based on source, the natural segment held the largest share of approximately 97% of the nicotinic acid market in 2024, owing to rising consumer preference for clean-label and plant-based ingredients.
• Based on form, the dry form segment leads the global market owing to its extended shelf life, ease of transportation, and cost-effectiveness in bulk handling.
• Based on application, the animal feed segment is driven by its critical role in improving animal metabolism and productivity.
• Based on distribution channel, the online retail segment is gaining significant traction in the market due to increasing digital penetration and consumer inclination toward e-commerce.

Nicotinic Acid Market Trends

Increasing Use in Animal Feed

The use of nicotinic acid in animal feed is gaining momentum due to its essential role in metabolic functions and overall animal health. It is widely incorporated into poultry and livestock diets to improve growth rates, reproductive performance, and feed efficiency.

• For example, a study published in Frontiers in October 2024 investigated Taihe black-bone silky fowls subjected to heat stress and found that supplementing their diet with 400–800 mg/kg of nicotinic acid significantly enhanced meat quality, boosted antioxidant enzyme activity, and supported favorable muscle fiber transitions.

These findings highlight this compound’s potential in improving poultry resilience and productivity under heat stress conditions. With climate change increasing the frequency of heatwaves, livestock producers are increasingly turning to nutritional interventions like niacin to maintain productivity and animal welfare in challenging environments.

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Nicotinic Acid Market Growth Factor

Rising Prevalence of Cardiovascular Diseases

The surging incidence of cardiovascular diseases globally is a significant driver for the global market. Nicotinic acid, also known as niacin, is clinically proven to reduce LDL (bad cholesterol), triglycerides, and increase HDL (good cholesterol), making it a crucial component in lipid-modifying therapy.

• According to the World Health Organization, cardiovascular diseases (CVDs) are the leading reason of death worldwide, claiming approximately 17.9 million lives annually, with high cholesterol being a leading risk factor. In the U.S., the CDC reports that around 86 million adults have total cholesterol levels above 200 mg/dL.

With rising lifestyle-related diseases, sedentary habits, and poor dietary patterns, the demand for cholesterol-lowering agents like niacin is expected to grow, especially in prescription drugs and dietary supplements for cardiovascular health management.

Market Restraint

Side Effects and Tolerance Issues

Despite its therapeutic benefits, nicotinic acid (niacin) is often associated with side effects that can limit its widespread use. One of the most common issues is skin flushing, which can be uncomfortable and discourages continued use. At higher doses, this compound has been linked to liver toxicity, gastrointestinal disturbances, and insulin resistance, especially in patients with pre-existing conditions.

These adverse reactions often result in poor patient compliance and hesitation among healthcare providers to recommend it as a long-term solution. Additionally, the availability of alternative cholesterol-lowering drugs with fewer side effects further restricts the market growth.

Market Opportunity

Emerging Markets and Fortification Policies

Governments in emerging economies are increasingly mandating food fortification to address micronutrient deficiencies, creating a strong opportunity for industry producers.

• India, for instance, operationalised updated standards in 2021 requiring staples such as wheat flour, rice, atta, and maida to be fortified with niacin (Vitamin B3) at 12.5–20 mg per 100 g. In June 2024, FSSAI further tightened its regulatory framework, mandating the use of approved test methods for verifying vitamin premixes in rice kernels.

These regulations elevate B3 demand in both public distribution and private markets. With rising disposable incomes and consumer awareness, fortified food and supplement sales are surging. This regulatory momentum in India and similar initiatives emerging across Asia and Africa offer a timely, scalable growth path for nicotinic acid suppliers targeting food, feed, and nutritional sectors.

Regional Analysis

The market in North America is witnessing steady growth due to increasing health consciousness and rising adoption of preventive healthcare supplements. The region’s advanced pharmaceutical sector is integrating nicotinic acid in lipid-modifying therapies to address high cholesterol levels. Additionally, robust investment in nutraceutical R&D and growing demand for fortified foods and beverages are fueling market expansion. Regulatory support for vitamin enrichment in processed foods and widespread use of this compound in animal nutrition to enhance livestock productivity also contribute significantly to the market's regional development.

• The United States nicotinic acid market benefits from the high prevalence of lifestyle diseases and proactive consumer health trends. The CDC reports nearly 40% of U.S. adults have high cholesterol, supporting demand for niacin-based treatments. Major players like Nature’s Bounty and GNC offer diverse niacin supplements. Furthermore, the FDA’s approval of niacin as a cholesterol management aid and increasing integration in multivitamin products fuel market expansion across the pharmaceutical and wellness sectors.
• Canada's market is witnessing growth due to increased adoption of health supplements and government-backed nutrition programs. Health Canada’s push for vitamin fortification, especially in indigenous and northern communities, supports demand. Brands like Jamieson Wellness include niacin in multivitamin formulations. Additionally, Canada's aging population fuels the nutraceutical sector, where this compound is used for cardiovascular health, cholesterol control, and energy metabolism.

Asia-Pacific Nicotinic Acid Market Trends

The Asia Pacific region is experiencing rapid growth in the market due to increasing consumer awareness of vitamin deficiencies and rising disposable incomes. The booming pharmaceutical and nutraceutical industries are incorporating niacin in supplements and cholesterol-lowering medications. Growing urbanization and lifestyle-related diseases are driving demand for fortified food and beverages. Additionally, the livestock sector is increasingly utilizing this compound to boost animal health and productivity, supported by government efforts to enhance food safety and nutritional quality through animal feed additives.

• China's nicotinic acid sector is expanding rapidly, driven by growing demand in animal feed and pharmaceuticals. Leading Chinese manufacturers like Brother Enterprises and Jubilant Life Sciences (with operations in China) are scaling production. The country’s rising focus on livestock nutrition and government-backed health supplementation initiatives is boosting market growth. For instance, feed additive regulations now encourage vitamin B3 use to enhance poultry growth and prevent metabolic disorders.
• India's market for nicotinic acid is witnessing strong growth, propelled by its booming nutraceutical and pharmaceutical sectors. Major Indian companies like Jubilant Pharmova and Piramal Pharma produce niacin for domestic and global use. The rise in lifestyle diseases and government campaigns like the “Food Fortification Resource Centre” promote vitamin enrichment in staple foods. Additionally, increasing demand for affordable lipid-modifying agents is supporting wider application of this acid in India’s healthcare system.

Europe Nicotinic Acid Market Trends

Europe’s market is growing steadily, driven by stringent regulations promoting food fortification and preventive healthcare practices. The region’s strong emphasis on clean-label and functional food products supports the use of vitamins like this compound in cereals, beverages, and snacks. Demand is further boosted by the aging population and rising awareness of cardiovascular health. Additionally, the animal feed industry increasingly adopts this compound to support metabolic efficiency and growth in livestock, aligning with regional goals of improving food security and sustainable farming practices.

• Germany's nicotinic acid industry is growing due to increased health awareness and strong demand for cholesterol-lowering supplements. The country has a high prevalence of hyperlipidemia, with around 20% of adults affected, according to the Robert Koch Institute. German pharmaceutical companies like BASF are investing in vitamin production, while fortified food trends are accelerating demand across retail chains such as DM and Rossmann.
• The UK market benefits from government-supported nutritional initiatives and rising supplement usage. Public Health England promotes vitamin intake through food fortification programs, encouraging inclusion of B-vitamins like niacin. Additionally, British consumers are adopting functional foods and OTC supplements from brands like Holland & Barrett to manage cholesterol and energy metabolism, boosting market growth across pharmaceutical, nutraceutical, and fortified food sectors.

Source Insights

The natural segment holds a dominant share in the global market owing to rising consumer preference for clean-label and plant-based ingredients. Increasing demand for naturally sourced vitamins in dietary supplements and fortified foods is driving this growth. Consumers associate natural sources with better bioavailability and fewer side effects, which enhances market appeal. Regulatory support for natural additives in food and pharma applications is also bolstering the segment's dominance across both developed and emerging markets.

Form Insights

The dry form segment leads the global market owing to its extended shelf life, ease of transportation, and cost-effectiveness in bulk handling. This form is preferred in pharmaceutical formulations, animal feed additives, and dietary supplements for its high stability and compatibility with other dry ingredients. Manufacturers also favour the dry form due to its low production cost and versatility in blending. These advantages contribute significantly to its widespread adoption across various end-use industries.

Application Insights

Animal feed represents the dominant application segment in the market, driven by its critical role in improving animal metabolism and productivity. Nicotinic acid enhances feed efficiency, supports energy utilization, and prevents nutritional deficiencies in livestock. Rising meat and dairy consumption worldwide has led to increased demand for fortified animal feed, particularly in the poultry and swine sectors. Furthermore, growing awareness about livestock health and quality output continues to support this segment's robust market position.

Distribution Channel Insights

Online retail is gaining significant traction in the market due to increasing digital penetration and consumer inclination toward e-commerce. The convenience of home delivery, product variety, and competitive pricing are major factors boosting online sales. Consumers, especially those purchasing dietary supplements and wellness products, prefer online platforms for better accessibility and information. Moreover, the growing presence of health-focused e-commerce platforms and direct-to-consumer brands is extending the reach of nicotinic acid-based products globally.

Company Market Share

Companies in the global market are focusing on expanding production capacities, enhancing purity levels, and investing in R&D to develop advanced formulations with reduced side effects. Many are forming strategic partnerships and entering emerging markets to tap into growing demand from nutraceutical, pharmaceutical, and animal nutrition sectors. Additionally, efforts are being made to comply with stringent regulatory standards and promote vitamin-fortified products to cater to health-conscious consumers.

Jubilant Life Sciences Limited

Jubilant Life Sciences Limited, now operating as Jubilant Pharmova Limited, is a key player in the global market, known for being one of the world’s largest manufacturers of Vitamin B3 (nicotinic acid and niacinamide). Headquartered in India, the company serves the pharmaceutical, animal nutrition, and food sectors across over 95 countries. With integrated operations and strong R&D capabilities, Jubilant leverages cost-effective manufacturing and global distribution networks to maintain a competitive edge in the vitamin and active pharmaceutical ingredient markets.

• In January 2025, Jubilant unveiled a significant expansion of its operations in India, specifically at its Bharuch facility in Gujarat. As part of this development, the company is setting up a new cGMP-compliant plant dedicated to producing nutraceuticals and dietary ingredients for human use. The facility will primarily manufacture Niacinamide (Vitamin B3), catering to a range of applications such as human nutrition, cosmetics, and infant food products.

List of key players in Nicotinic Acid Market

1. Lonza Group AG
2. Jubilant Life Sciences Limited
3. Vertellus Holdings LLC
4. DSM Nutritional Products
5. Shandong Hongda Biotechnology Co., Ltd.
6. Lasons India Pvt. Ltd.
7. Resonance Specialties Limited
8. Tianjin Zhongrui Pharmaceutical Co., Ltd.
9. Vanetta Ltd.
10. Zhejiang NHU Company Ltd.

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Recent Developments

• April 2025- Zydus Lifesciences secured final US FDA approval to manufacture Generic Niacin Extended‑Release Tablets (500 mg, 750 mg, and 1,000 mg) at its Moraiya facility in Ahmedabad. These tablets address cholesterol issues, reducing LDL and triglycerides while raising HDL, and tap into a U.S. market with annual sales around USD 5.5 million.