The global bone cement and glue market size was valued at USD 1.3 billion in 2023 and is projected to reach a value of USD 2.3 billion by 2032, registering a CAGR of 5.9% during the forecast period (2024-2032). Some factors driving the global bone cement and glue market share include an increase in the number of elderly individuals and an increase in road accidents caused by heavy traffic, sports injuries, and trauma.
Bone cement and glue are medicinal materials used in orthopedic operations to consolidate and strengthen bone structures, implants, and fractures. They function as adhesives or fillers, giving structural support and increasing the stability of implants or bone fragments during and after surgery.
Rapid growth in the geriatric population is the vital factor escalating the market growth, as well as rising developments in the field of regenerative medicine, rising number of road traffic accidents, rising prevalence of osteoporosis, increase in the incidence of periodontics among young adults, growing demand for orthopedic bone cement and casting materials, rising number of domestic and global players entering the market with new ingredients such as antibiotic-impregnated bone cement Furthermore, increased growth potential in emerging nations, as well as expanding R&D efforts, will open up new chances for the bone cement and glue market throughout the projection period.
However, rising unfavorable reimbursement scenarios, increased costs, and extensive clinical data requirements for launching new bone cement are among the significant factors that will obstruct market growth, while rising development of novel biomaterials with high mechanical properties and adhesion strength will further challenge the growth of the bone cement and glue market during the forecast period mentioned above.
The rising frequency of orthopedic disorders like osteoporosis, osteoarthritis, and fractures, especially among the elderly, drives demand for bone cement and glue. As the world's population ages and lifestyles change, there is an increasing demand for orthopedic therapies such as joint replacement surgery and fracture repair, both of which necessitate using bone cement and glue.
Additionally, musculoskeletal problems, such as fractures, osteoarthritis, and lower back pain, are among the primary causes of disability globally. In 2022/23, 27% of workers had musculoskeletal problems, the primary cause of work-related illness. The frequency of musculoskeletal diseases is expected to rise by 115% between 2020 and 2050, reaching 1060 million instances. Osteoarthritis (OA) is the most common type of arthritis, affecting around 500 million individuals globally, or roughly 7% of the population. According to a 2023 study, 15% of adults aged 30 and up have OA; by 2050, this figure might rise to approximately one billion. OA affects approximately 22% of adults over 60 and is more common in women, with 23% affected compared to 18% of men.
Furthermore, the American Academy of Orthopaedic Surgeons (AAOS) estimates that over 700,000 knee replacements are performed yearly in the United States. Thus, the increasing prevalence of orthopedic problems is boosting global demand for bone cement and adhesive products.
Hospitalization costs, implant costs, surgical fees, and post-operative care can be expensive for orthopedic operations like joint replacement surgeries and fracture repair. The high expense of these procedures can be a significant barrier to access for patients, healthcare providers, and payers, limiting the use of modern orthopedic therapies and bone cement and glue solutions. Hip replacements, knee replacements, spinal fusions, and repairing hip and femur fractures or dislocations are the most expensive orthopedic surgery performed worldwide. A knee replacement can cost USD 20,000 in the United States but only USD 9,000 in Mexico.
Furthermore, the average hospital cost for a primary total knee replacement (TKA) in the United States varies from USD 11,317 in Montgomery, Alabama, to USD 69,654 in New York, New York. These patients' average hospital stay is 4.27 days, ranging from 3 to 10 days. These costs may exclude extra charges such as medical fees, anesthesia, imaging, and rehabilitation services, which can raise the total cost of care.
In addition, orthopedic surgery expenses in India vary greatly based on the treatment, location, and other considerations. For example, a complete knee replacement surgery in India can cost between INR 1,50,000 and INR 4,00,000, whereas a total hip replacement surgery can cost between INR 2,00,000 and INR 6,00,000. According to Indicure, orthopedic surgery in India costs between 60% and 90% less than in the United States, United Kingdom, Canada, Australia, or any other Western country.
Moreover, orthopedic operations can be prohibitively expensive for patients, healthcare providers, and payers, limiting access to sophisticated orthopedic therapies, bone cement, and adhesive solutions. Patients may face out-of-pocket costs, insurance deductibles, or co-payments that make orthopedic operations prohibitively expensive. Healthcare providers and payers may face financial or reimbursement constraints that limit their capacity to offer or cover costly orthopedic therapies.
The world's aging population is a primary driver of demand for joint replacement surgeries such as total hip arthroplasty (THA) and knee arthroplasty. As people age, they are more likely to develop degenerative joint illnesses like osteoarthritis, which can cause pain, stiffness, and limited mobility. Joint replacement operations are excellent treatments for symptom relief and functional restoration, and bone cement and adhesive are essential for anchoring orthopedic implants and fostering bone healing.
Additionally, countries with aging populations, including Japan, the United States, and numerous European countries, have seen an increase in joint replacement surgeries in recent years. In 2023, 1.1 billion people will be 60 or older, accounting for 13.9% of the world's population of 7.9 billion. By 2050, the global elderly population will quadruple to 2.1 billion, accounting for 22% of the population. In developing countries, 3.7% of the population is 65 years or older, compared to 9% in other developing countries and 20% in industrialized nations. According to the World Health Organization (WHO), 73% of people with osteoarthritis (OA) are over the age of 55, with women accounting for 60%.
As the prevalence of degenerative joint illnesses increases, so will the number of orthopedic treatments that require bone cement and adhesive. This trend emphasizes the critical role of these products in meeting the clinical demands of seniors with musculoskeletal problems, boosting mobility, and improving quality of life.
| Study Period | 2020-2032 | CAGR | 5.9% |
| Historical Period | 2020-2022 | Forecast Period | 2024-2032 |
| Base Year | 2023 | Base Year Market Size | USD 1.3 billion |
| Forecast Year | 2032 | Forecast Year Market Size | USD 2.3 billion |
| Largest Market | North America | Fastest Growing Market | Asia Pacific |
North America is the most significant global bone cement and glue market shareholder and is estimated to grow at a CAGR of 5.6% over the forecast period. North America dominated the bone cement & glue market due to sophisticated healthcare infrastructure, a high prevalence of chronic diseases, increased heart disorders, rising healthcare investments, rising demand for plastic surgeries, and a growing senior population. Furthermore, increased patient knowledge of musculoskeletal problems and potential therapies, rising demand for surgical procedures, and the existence of prominent players are all driving market expansion. Significantly, increasing emergency room visits for fracture diagnosis drives market growth.
Furthermore, the market is expected to grow in the United States due to breakthroughs in osteoporosis therapies, the rapid expansion of orthopedic specialty clinics, government initiatives to support sports, and high demand for arthroplasty procedures. The market is being driven by an increase in motor vehicle accidents resulting in catastrophic joint and spinal cord injuries, as well as the local presence of numerous significant enterprises with established distribution networks and advantageous reimbursement policies. Also, in 2021-2022, more than 117,000 hip and knee replacements were performed in Canada, a 5.9% increase over the previous year. In 2021-2022, a hip or knee replacement cost USD 11,979, while rehabilitation for an inpatient surgery was USD 12,402.
Asia-Pacific is anticipated to exhibit a CAGR of 6.1% over the forecast period. Regarding revenue growth, China and India are expected to outperform the rest of Asia-Pacific. Every year, about 200,000 people in India get knee arthroplasty procedures. Over 250,000 people in India will undergo total knee replacement (TKR) surgeries in 2022, more than double the number of TKR surgeries conducted in prior years.
Additionally, according to the Arthritis Foundation, hip replacements will grow by 171 percent by 2030, while knee replacements may climb by 189 percent. PMMA bone cement is commonly employed in knee injury cases; thus, such cases are expected to drive demand for PMMA bone cement, resulting in market growth throughout the forecast period.
Europe has a sizable part of the bone cement and glue market. The region's aging population and a high incidence of orthopedic ailments boost demand for these products. The presence of significant market players, as well as ongoing research and development initiatives, all contribute to market growth in Europe.
Latin America provides significant growth potential for the bone cement and glue market. The region's growing healthcare expenditure, increased awareness of orthopedic therapies, and the presence of a large underserved population all help to drive market expansion.
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The market is further segmented into Bone Cement and Bone Glue. Bone cement accounts for 50% of the global market, owing to a rise in arthroplasty procedures and osteoporosis patients worldwide. Bone cement, known as polymethylmethacrylate (PMMA) cement, is a biocompatible substance widely used in orthopedic treatments to anchor implants and bridge gaps between bone and prosthetic components. It is usually made up of a powder component (polymer) and a liquid monomer, combined to form a dough-like product that hardens quickly when exposed to body warmth.
Bone glue, also known as surgical adhesive or sealant, is a bonding substance used to connect bone fragments or reinforce implants without the use of mechanical fixation, such as screws or pins. It can be constructed of various materials, including cyanoacrylate, fibrin, and collagen-based substances. Bone glue is applied directly to the bone surface or fracture site and instantly attaches, forming a solid bond that promotes bone healing and stabilization.
The market can be bifurcated into Arthroplasty, Kyphoplasty, and Vertand ebroplasty. The significant frequency of autoimmune diseases such as rheumatoid arthritis among women is expected to drive up demand for arthroplasty over the predicted period. Arthroplasty is the surgical repair or replacement of a joint to improve function and relieve pain caused by arthritis or joint deterioration. In the context of bone cement and glue, arthroplasty primarily refers to joint replacement surgeries, such as total hip arthroplasty (THA) and total knee arthroplasty (TKA). Bone cement is often used in arthroplasty surgeries to attach orthopedic implants, such as artificial hips and knees, to the surrounding bone. It offers stability, fixation, and load distribution, enabling early mobility and enhanced joint function.
Additionally, arthroplasty operations are necessary for individuals with severe osteoarthritis, rheumatoid arthritis, or traumatic joint injuries, as they provide considerable benefits in quality of life and mobility. This feature may motivate patients to undergo total knee arthroplasty to restore joint function, increasing the need for bone cement.
Kyphoplasty is a minimally invasive surgical surgery that treats vertebral compression fractures (VCFs) caused by osteoporosis, trauma, or tumor infiltration. Kyphoplasty involves inserting a balloon catheter into the broken vertebral body and inflating it to form a cavity, followed by injecting bone cement to fix the fracture and restore vertebral height. Bone cement provides structural support, pain alleviation, and fracture stabilization, alleviating symptoms like back pain, spinal deformity, and loss of mobility. Kyphoplasty is a viable therapeutic option for patients with symptomatic VCFs, providing immediate pain relief, improved spine alignment, and improved functional outcomes.
The market is fragmented into Hospitals, Clinics, and Ambulatory Surgery Centers. Hospitals are an essential end-user segment for bone cement and adhesive products. Orthopedic operations that require bone cement and adhesive, such as joint replacement surgery, fracture repair, and spinal fusion, are frequently performed in hospitals. Hospitals often offer specialist orthopedic departments outfitted with advanced surgical facilities, imaging technologies, and post-operative care services, making them ideal for complex orthopedic procedures. Surgeons and orthopedic teams in hospitals have vast knowledge and competence in performing orthopedic surgeries, assuring high-quality care and the best patient outcomes.
Furthermore, hospitals act as referral facilities for patients with orthopedic disorders, providing complete multidisciplinary care and access to specialized medical knowledge. Rising income levels, increased health knowledge, increased prevalence of lifestyle disorders, improved insurance coverage, and a larger senior population needing osteotomy procedures all contribute to increased hospital demand.
Clinics, including orthopedic clinics and specialist outpatient facilities, are critical in providing orthopedic care and utilizing bone cement and adhesive solutions. Orthopedic clinics diagnose, treat, and perform surgery on patients suffering from musculoskeletal illnesses such as arthritis, fractures, sports injuries, and degenerative spine conditions. Clinics may provide a variety of orthopedic treatments and procedures, such as joint injections, arthroscopic surgery, and fracture management, and frequently collaborate with hospitals or ambulatory surgery centers.
Consequently, bone cement and adhesive products are commonly used in clinics for minor orthopedic operations, outpatient surgeries, and follow-up care, providing patients with convenience, accessibility, and individualized treatment options.
