Home Pharmaceuticals Cell Isolation/Cell Separation Market Size to Boost at US $31.31 billion by 2031

Cell Isolation/Cell Separation Market Size, Share & Trends Analysis Report By Product (Consumables, Instruments), By Cell Type (Animal Cells, Human Cells), By Separation Technique (Centrifugation-Based Cell Isolation, Surface Marker-Based Cell Isolation, Filtration-Based Cell Isolation, Others), By Application (Biomolecule Isolation, Cancer Research, Stem Cell Research, Tissue Regeneration, In Vitro Diagnostics, Others), By End-User (Research laboratories and institutes, Biotechnology and biopharmaceutical companies, Cell banks, Hospitals and diagnostic laboratories) and By Region(North America, Europe, APAC, Middle East and Africa, LATAM) Forecasts, 2023-2031

Report Code: SRPH1210DR
Last Updated : Jan 16, 2023
Author : Straits Research
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Market Overview

The global cell isolation/cell separation market size was valued at USD 7.8 billion in 2022. It is estimated to reach USD 31.31 billion by 2031, growing at a CAGR of 16.7% during the forecast period (2023–2031).

Removing individual cells from a heterogeneous suspension of cells or tissues is called cell separation or cell isolation. Cell isolation is a crucial step in biological research's cellular biology phase for studies like cell characterization, cell counting, and cell storage and preservation of a particular type. The design and development of biologics, the production of therapeutic proteins, in-vitro diagnostics, and other research applications all benefit from cell separation.

Testing the various blood components by medical prescriptions is the common goal of this technique. Cell characteristics like surface markers, surface charge and adhesion, density, and size affect how easily cells can be isolated. A few factors anticipated to boost market growth during the forecast period include rising chronic disease incidence and prevalence due to an aging population, technological advancements in cell separation technologies, and rising demand for biopharmaceuticals and personalized medicine.


Market Dynamics

What Are the Driving Factors for Cell Isolation/Cell Separation?

The Prevalence of Chronic Diseases Has Increased

Increased sedentary lifestyle, aging of the global population, increase in alcohol consumption, and increase in cigarette smoking are all contributing factors to the rise in chronic diseases like diabetes, obesity, arthritis, cardiac diseases, and cancer. According to Imperial College London, seven out of ten deaths worldwide are expected to be caused by chronic diseases in 2020, accounting for about 41 million deaths annually. Nearly 17 million of these deaths are considered premature, with the average person passing away at a younger age than anticipated. As a result, the need for cellular therapies to treat chronic diseases is growing along with the burden of chronic diseases. This is directing attention and funding toward research to create efficient treatments. Therefore, the global market for cell separation technologies is being driven by increased cellular research activities.

An Increase in The Geriatric Population Boost Demand for Clinical Trials

The geriatric population is more likely than the younger population to experience chronic illnesses like cancer and neurological disorders. Furthermore, the geriatric population is proliferating compared to the younger population. Alzheimer's, dementia, cancer, and immune diseases are predicted to become more prevalent as the population ages 65 and over increases. This is expected to increase the need for corrective treatment for these disorders. This will probably increase the demand for cell separation products used in clinical trials and other types of research. These elements are anticipated to drive the market for cell separation technologies worldwide. According to the United Nations, the geriatric population over 60 is anticipated to grow to 2.1 billion in 2050.

What Are the Challenges for the Cell Isolation/Cell Separation Market?

High Cost of Cell-Based Research and Cell-Separation Equipment

In-depth research is done in cell biology to create novel treatments like stem cell and gene therapies. The tools, reagents, and other products used in this research must be of the highest caliber to get reliable results. Cell biology research costs are high because it must uphold high standards and adhere to regulations set forth by regulatory bodies. Additionally, very little cell-based research has been successful, and most cell therapy trials have a low success rate. Budget restrictions prevent many institutions and small businesses from purchasing expensive goods. This is particularly true in developing nations, where lackluster healthcare spending and underdeveloped infrastructure facilities limit the use of cutting-edge technology. As a result, these nations only occasionally use robotic kits and tools. This is one of the main things holding back the market for cell isolation instruments.

What Are the Future Opportunities for Cell Isolation/Cell Separation?

Use In Regenerative Medicine Development Stem Cell Research Engine

In the development of regenerative medicine, which replaces tissues or organs rather than treating them, stem cells are a well-known cell therapy. As a result, the stem cell research sector held a sizable portion of the global market in 2022. The geriatric population is anticipated to grow significantly faster than the adult population, which is anticipated to increase the demand for stem cell therapy. The demand for cell separation technology is anticipated to increase globally due to the significantly more extensive clinical trials stem cells require. Government and private funding for stem cell research are anticipated to increase, creating significant opportunities for stem cell separation technologies.

Study Period 2019-2031 CAGR 16.7%
Historical Period 2019-2021 Forecast Period 2023-2031
Base Year 2022 Base Year Market Size USD XX Billion
Forecast Year 2031 Forecast Year Market Size USD 31.31 Billion
Largest Market North America Fastest Growing Market Asia Pacific
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Regional Analysis

The global cell isolation/cell separation market is bifurcated into four regions: North America, Europe, Asia-Pacific, and LAMEA.

North America Dominates the Global Market

North America is the most significant shareholder in the global cell isolation/cell separation market share and is expected to grow at a CAGR of 16.21% during the forecast period. The U.S. and Canada are included in the analysis of the cell isolation/cell separation market growth in North America. The increasing emphasis on drug discovery, the established and well-developed research infrastructure, and the presence of international biotechnology companies like Pfizer, Mylan, Amgen, and others in the American region all contribute to market dominance. Significant market players like Thermo Fischer, Corning Inc., Becton, Dickinson and Company Limited, STEMCELL Technologies Inc., and others are in the regional market. This gives the area a significant competitive advantage and further boosts revenue generation. Additionally, there is a greater need for cell separation solutions for research and clinical applications due to the high prevalence of chronic and infectious diseases, including the COVID-19 outbreak.

Asia Pacific is expected to grow at a CAGR of 16.93% during the forecast period. China, Australia, India, Japan, and the rest of Asia-Pacific are all included in the Asia-Pacific cell isolation/cell separation market analysis. As clinical research organizations and biopharmaceutical firms like Biocon, IPCA, Lupin, and others expand their cell separation techniques in downstream processing and R&D in this region, the market is predicted to proliferate. Numerous biopharmaceutical companies are drawn to this region due to the availability of skilled labor at reasonable prices and the lack of strict regulations for drug development. This encourages increased market product adoption, which fuels the sector's expansion in this area. The market product adoption in these regional countries is also boosted by extensive research projects involving cell-based studies and the region's growing Stem Cell research activity.

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Segmental Analysis

The market is segmented by product, cell type, separation technique, application, and end user.

Based on product, the global cell isolation/cell separation market is bifurcated into consumables and instruments.

The consumables segment is the highest contributor to the market and is expected to grow at a CAGR of 16.4% during the forecast period. Due to frequent purchases of consumables, this market segment held the largest market share. Rising R&D expenditures are also driving the segment by biotechnology and biopharmaceutical firms for the creation of advanced biologics, such as monoclonal antibodies and vaccines. As a result, it is anticipated that there will still be a high demand for consumables during the forecast period.

Based on cell type, the global cell isolation/cell separation market is bifurcated into animal and human cells.

The human cell segment is the highest contributor to the market and is forecasted to grow at a CAGR of 16.82% during the forecast period. One of the main factors driving its largest share is the growing emphasis on human and cancer research and the numerous uses of isolated human cells in biopharmaceutical development, clinical trials, and research. The favorable reimbursement policies for personalized medicine in developed nations also increase the demand for human cell isolation.

Based on the separation technique, the global cell isolation/cell separation market is bifurcated into centrifugation-based cell isolation, surface marker-based cell isolation, filtration-based cell isolation, and others.

The centrifugation-based cell isolation segment is the highest contributor to the market and is anticipated to grow at a CAGR of 16.57% during the forecast period. This is because academic institutions, research facilities, and biotechnology and biopharmaceutical companies use this technique extensively. One of the most crucial steps in cell isolation is centrifugation. Cell isolation typically involves the use of differential centrifugation and density gradient centrifugation. While differential centrifugation uses a lysate to sever cell membranes to separate particles, density gradient centrifugation uses the molecular weights of the particles to be separated.

Based on application, the global cell isolation/cell separation market is bifurcated into biomolecule isolation, cancer research, stem cell research, tissue regeneration, in vitro diagnostics, and others.

The biomolecule isolation segment is the highest contributor to the market and is forecasted to grow at a CAGR of 16.33% during the forecast period. The primary factor causing the highest share is the increased attention paid to the production of biopharmaceuticals, such as monoclonal antibodies, recombinant proteins, and biosimilars. Additionally, expanding government funding for developing new drugs fuels market expansion. The study period is expected to see profitable growth in the stem cell and cancer research sectors. Growing corporate and academic investment in cell-based research is a significant factor in the segment's expansion.

Based on end users, the global cell isolation/cell separation market is bifurcated into research laboratories & institutes, biotechnology & biopharmaceutical companies, cell banks, hospitals & diagnostic laboratories.

The research laboratories & institutes segment is the highest contributor to the market and is anticipated to grow at a CAGR of 16.64% during the forecast period. This results from increased R&D efforts by academic institutions to create cutting-edge cancer and neurological treatments. The segment is also expected to be significantly influenced by the expanding number of research institutes and laboratories worldwide. For instance, the New York Stem Cell Foundation (NYSCF), which focuses on conducting the most cutting-edge stem cell research, opened a new Research Institute in Manhattan.

Market Size By Product

Market Size By Product
  • Consumables
  • Instruments

  • Impact of covid-19

    Before the pandemic, several developments took place on an international level. The U.S.-China trade war has affected all economies. The U.K.'s exit from the EU is expected to result in a considerable slowdown for the British economy before it gains ground. However, France, Italy, and Germany are expected to benefit from the scenario. And Germany's dominance in the automobile, electronics, and pharmaceuticals sectors will prove beneficial for the Resistive Load Banks market. The U.S.-China trade war and Brexit hint at the global economy moving towards protectionism. 

    The pandemic has put several restraints on the global economy and brought international trade to a standstill. Manufacturers of resistive load banks are expected to have begun evaluating alternative raw materials suppliers. In addition, more prominent companies, which have a large balance sheet, are likely to adopt strategies such as vertical integration, which will gain control of the supply chain and aid in gaining a deeper understanding of domestic markets. These players are expected to absorb smaller players, with smaller businesses either shutting down temporarily or permanently. Key players are also likely to turn to increased automation, keeping in mind the uncertainty of the global economy and the workforce. This will also be done to improve just-in-time solutions (JIT) and is expected to aid in the provision of customizations.


    List of key players in Cell Isolation/Cell Separation Market

    1. Thermo Fisher Scientific, Inc. (The U.S.)
    2. Becton, Dickinson and Company Limited (The U.S.)
    3. Beckman Coulter Inc. (Danaher Corporations) (The U.S.)
    4. Merck KGaA (Germany)
    5. Terumo BCT (Japan)
    6. GE Healthcare (The U.S.)
    7. Bio- Rad Laboratories Inc. (The U.S.)
    8. Corning Inc. (The U.S.)
    9. Hoffmann-La Roche Ltd. (Switzerland)
    10. Miltenyl Biotech (Germany)
    11. STEMCELL Technologies Inc. (Canada)
    12. Invent Biotechnologies (The U.S.)

    Cell Isolation/Cell Separation Market Share of Key Players

    Cell Isolation/Cell Separation Market Share of Key Players

    Recent Developments

    • May 2022, The development of a new human B cell isolation product and an updated protocol for its current human isolation kits have been announced by Akadeum Life Sciences, Inc., a leader in buoyancy-based technology for cell therapy manufacturing, clinical diagnostics, and cell & molecular research for human health and life sciences.
    • April 2022, The MARS platform from Applied Cells and the EasySep immunomagnetic cell separation kits from STEMCELL will be combined to create a new, high-performance cell separation solution, according to a joint announcement from the two companies.

    Cell Isolation/Cell Separation Market Segmentations

    By Product (2019-2031)

    • Consumables
    • Instruments

    By Cell Type (2019-2031)

    • Animal Cells
    • Human Cells

    By Separation Technique (2019-2031)

    • Centrifugation-Based Cell Isolation
    • Surface Marker-Based Cell Isolation
    • Filtration-Based Cell Isolation
    • Others

    By Application (2019-2031)

    • Biomolecule Isolation
    • Cancer Research
    • Stem Cell Research
    • Tissue Regeneration
    • In Vitro Diagnostics
    • Others

    By End-User (2019-2031)

    • Research laboratories and institutes
    • Biotechnology and biopharmaceutical companies
    • Cell banks
    • Hospitals and diagnostic laboratories

    Frequently Asked Questions (FAQs)

    What is the growth rate for the Cell Isolation/Cell Separation Market?
    Cell Isolation/Cell Separation Market size will grow at approx. CAGR of 16.7% during the forecast period.
    Some of the top industry players in Cell Isolation/Cell Separation Market are, Thermo Fisher Scientific, Inc. (The U.S.), Becton, Dickinson and Company Limited (The U.S.), Beckman Coulter Inc. (Danaher Corporations) (The U.S.), Merck KGaA (Germany), Terumo BCT (Japan), GE Healthcare (The U.S.), Bio- Rad Laboratories Inc. (The U.S.), Corning Inc. (The U.S.), Hoffmann-La Roche Ltd. (Switzerland), Miltenyl Biotech (Germany), STEMCELL Technologies Inc. (Canada), Invent Biotechnologies (The U.S.), etc.
    North America has held a dominant position in the Cell Isolation/Cell Separation Market, with the largest market share.
    The Asia Pacific region has experienced the highest growth rate in the Cell Isolation/Cell Separation Market.
    The global Cell Isolation/Cell Separation Market report is segmented as follows: By Product, By Cell Type, By Separation Technique, By Application, By End-User


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