DNA and Gene Cloning Services Market Size & Outlook, 2026-2034

DNA and Gene Cloning Services Market Overview

The global DNA and gene cloning services market size is valued at USD 2.88 billion in 2025 and is estimated to reach USD 9.91 billion by 2034, growing at a CAGR of 14.76% during 2026-2034. The global market observed impressive growth, stimulated by the rising demand for synthetic microbial chassis development for precision metabolic engineering.

Key Market Trends & Insights

• North America held a dominant share of the global market, accounting for 42.08% in 2025.
• The Asia Pacific region is estimated to grow at the fastest pace, with a CAGR of 16.74% during the forecast period.
• Based on service, the custom cloning segment is expected to register the fastest CAGR of 15.21%.
• By application, the mutagenesis segment is estimated to grow at the fastest CAGR of 15.08% during the forecast period.
• Based on end use, the academic & research institutes segment dominated the market in 2025, with a revenue share of 41.96%.
• The U.S. dominates the DNA and gene cloning services market, valued at USD 948.44 million in 2024 and reaching USD 1,084.35 million in 2025.

Table: U.S. DNA and Gene Cloning Services Market Size (USD Million)

Source: Straits Research

Market Size & Forecast

• 2025 Market Size: USD 2.88 billion
• 2034 Projected Market Size: USD 9.91 billion
• CAGR (2026-2034): 14.76%
• Dominating Region: North America
• Fastest Growing Region: Asia Pacific

The DNA and gene cloning services market comprises specialized services such as gene synthesis, custom cloning, sub-cloning, and other related offerings. These services are extensively applied in DNA sequencing, mutagenesis, genotyping, and various genetic research applications. The market primarily serves academic and research institutes, pharmaceutical and biotechnology companies, as well as contract manufacturing and research organizations, supporting advancements in genomics, personalized medicine, and biotechnology.

Latest Market Trends

Rise of Automated High-Throughput Gene Cloning Platforms

A key trend in the DNA and gene cloning services market is the growing adoption of automated high-throughput gene cloning platforms. These systems enable faster, more accurate synthesis and assembly of DNA sequences, reducing human error and turnaround time. Driven by increasing demand for large-scale genomic research and personalized medicine, automation is enhancing efficiency, reliability, and scalability, allowing service providers to meet the rising demand of pharmaceutical companies, academic institutions, and biotechnology firms globally.

Rising Adoption of Synthetic Biology-Driven Gene Ploning

The growing integration of synthetic biology in DNA and gene cloning services is transforming genetic research and therapeutic development. By enabling the design and construction of customized genetic circuits and synthetic genes, researchers can accelerate drug discovery, gene therapy, and metabolic engineering projects. This trend is driven by the increasing demand for precision, scalability, and rapid turnaround in academic, pharmaceutical, and biotechnology applications, boosting market growth and innovation.

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Market Drivers

Increasing Investment in Personalized Medicine and Gene Therapy

The rising focus on personalized medicine and gene therapy is a key driver of the DNA and Gene Cloning Services market. Growing demand for customized genetic solutions enables targeted treatments for complex diseases, including rare genetic disorders and cancer. Pharmaceutical companies, biotechnology firms, and research institutions are increasingly adopting advanced cloning services to develop precision therapies, accelerate drug discovery, and enhance treatment efficacy, thereby propelling market growth globally.

Market Restraints

Limited Standardization in Cloning Protocols

A niche restraint in the DNA and gene cloning services market is the lack of standardized protocols across laboratories and service providers. Variations in cloning techniques, vector systems, and quality control measures can lead to inconsistent results, impacting the reproducibility and reliability of genetic research. This inconsistency poses challenges for large-scale studies and collaboration between institutions, limiting market adoption and slowing the integration of advanced cloning services in pharmaceutical and academic applications.

Market Opportunity

Expansion into AI‑Enabled Automated Cloning Services

A major opportunity in the DNA and gene cloning services market is the rapid adoption of AI‑powered automated cloning platforms that drastically improve design precision, reduce timelines, and lower costs. Recent launches of AI‑assisted vector design systems and end‑to‑end automated workflows are enabling providers to offer high‑fidelity custom constructs with faster turnaround, attracting both large biopharma firms and smaller research labs seeking scalable, reliable gene assembly solutions.

Regional Analysis

North America dominated the DNA and gene cloning services market in 2025, accounting for 42.08% market share. This growth is driven by the presence of advanced genomic infrastructure and federally funded research programs, which provide access to cutting-edge sequencing and cloning technologies. This strong ecosystem enables faster adoption, innovation, and large-scale genomic projects across academic and pharmaceutical institutions.

In Canada, the major federal investment in the Canadian Precision Health Initiative, aimed at generating and sharing genomic data for over 100,000 individuals, is a major market driver. This large-scale population genomics effort enhances research capabilities, accelerates precision health studies, and expands demand for advanced cloning and sequencing services across Canadian institutions.

Asia Pacific Market Insights

Asis Pacific is emerging as the fastest-growing region with a CAGR of 16.74% from 2026-2034. The growth is driven by China’s large-scale national genomics initiatives, which establish advanced sequencing centers and high-throughput cloning facilities. These programs accelerate research, diagnostics, and therapeutic development, boosting regional service demand.

The Australian DNA and gene cloning services market is expanding due to the establishment of Genomics Australia, a national genomics agency launched in 2025 to integrate cutting-edge genomic research into healthcare and boost precision medicine. This strategic body strengthens the coordination of genomic technologies and drives demand for advanced gene cloning and sequencing services across research and clinical sectors.

Regional Market share (%) in 2025

Source: Straits Research

Europe Market Insights

In Europe, the DNA and gene cloning services market is accelerated by the EU’s “1+ Million Genomes” initiative, which aims to create a federated European genomic data infrastructure linking whole‑genome sequencing data from over a million citizens. This massive, collaborative genomics resource accelerates research, boosts demand for advanced cloning services, and supports personalized medicine development across European institutions.

In the UK, market growth is supported by the integration of genomics into routine clinical care through the NHS Genomic Medicine Service, which supports large‑scale genomic testing and research. This infrastructure expands demand for advanced cloning expertise, linking genomic data to novel therapeutic and diagnostic development.

Latin America Market Insights

In Latin America, the market growth is propelled by the emergence of large-scale national genomic biodiversity projects, such as Chile’s 1000 Genomes initiative to sequence the DNA of diverse native species. This unique effort expands regional genomics capabilities, increases local demand for sequencing and cloning services, and enhances research infrastructure across the region.

In Brazil, the DNA and gene cloning services market growth is supported by the strategic partnership between MGI Tech and major Brazilian institutions like Sabin Group and Fiocruz, which expands access to advanced genomic sequencing and cloning technologies for precision medicine and cancer diagnostics. These collaborations boost local capacity, improve data quality, and accelerate the adoption of cloning services in clinical and research settings.

Middle East and Africa Market Insights

In the Middle East, the market is expanding due to the expansion of regional genomic reference databases and collaborative research consortia such as the Catalogue for Transmission Genetics in Arabs (CTGA) and similar initiatives. These databases systematically document population‑specific genetic variants, boosting demand for localized cloning, sequencing, and functional genomics services tailored to regional health challenges and research priorities.

In Egypt, the DNA and gene cloning services market is growing due to the development of Egypt’s first accredited oncogenomics and next-generation sequencing research units, such as the Molecular Genomics Unit at Ain Shams University. These labs enhance local capacity for advanced genomic analysis, cloning research, and precision disease studies, reducing dependence on international services and boosting domestic demand for genetic workflows.

Service Insights

The gene synthesis segment dominated the market in 2025, accounting for 41.53% revenue share. This growth is driven by rising demand for codon-optimized synthetic genes for extremophile enzymes, enabling researchers to study proteins that function under extreme conditions, supporting industrial biotechnology and novel drug development applications.

The custom cloning segment is projected to witness the fastest CAGR of 15.21% during the forecast timeframe. This growth is augmented by increasing demand for rare epigenetically modified gene constructs, allowing researchers to study gene regulation patterns and develop targeted epigenetic therapies, particularly in oncology and neurodegenerative disease research.

By Service Market Share (%), 2025

Source: Straits Research

Application Insights

The DNA sequencing segment dominated the market in 2025 with a revenue share of 37.94%. This growth is driven by the increasing use of single-cell sequencing for microbiome and immune profiling, allowing researchers to analyze genetic heterogeneity at the cellular level, accelerating personalized medicine and immunotherapy development.

The mutagenesis segment is estimated to grow at a CAGR of 15.08% during the forecast period. This growth is stimulated by increasing adoption of high-throughput CRISPR-based functional screening, which allows researchers to systematically induce targeted mutations across genomes, accelerating gene function studies, drug target discovery, and the development of novel therapeutics.

End Use Insights

The academic & research institutes segment dominated the market in 2025, accounting for 41.96% revenue share in 2025 because of the expanding government and private funding for genomic research programs, which is enabling universities and research centers worldwide to adopt advanced DNA and gene cloning services for large-scale studies.

The pharmaceutical & biotechnology companies segment is expected to grow at the fastest CAGR during 2026-2034, due to rising demand for customized synthetic antibodies and therapeutic gene constructs, enabling accelerated biologics development, targeted therapies, and precision medicine applications in oncology and rare genetic disorders.

Competitive Landscape

The global DNA and gene cloning services market is moderately consolidated, with major players such as Thermo Fisher Scientific, GenScript Biotech, Bio‑Techne, Charles River Laboratories, and others. Competition is driven by technological advancements, strategic collaborations, and service expansion, including gene synthesis and automated cloning platforms. Continuous innovation, global reach, and tailored solutions enable these companies to strengthen market positioning.

VectorBuilder: An emerging market player

VectorBuilder is an emerging specialist in the market, offering a highly intuitive online platform for custom vector design and cloning that streamlines workflows for researchers worldwide. The company’s modular, high-efficiency cloning systems and rapid turnaround services empower biotech labs, academic researchers, and pharmaceutical developers to accelerate genetic construct production with reduced costs and simplified project management, enhancing its competitive foothold in the industry.

List of key players in DNA and Gene Cloning Services Market

1. Agilent Technologies Inc.
2. Bio‑Rad Laboratories Inc.
3. Bio‑Techne
4. Charles River Laboratories International
5. Danaher Corporation
6. Eurofins Scientific
7. GenScript Biotech Corporation
8. Integrated DNA Technologies (IDT)
9. Lonza Group
10. MedGenome
11. Merck KGaA
12. New England Biolabs Inc.
13. Origene Technologies Inc.
14. Sartorius AG
15. Takara Bio Inc.
16. Thermo Fisher Scientific Inc.
17. Twist Bioscience Corporation
18. Sino Biological
19. Creative Biogene
20. Others

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Strategic Initiative

• May 2025: Twist Bioscience expanded its collaboration with Ginkgo Bioworks, securing long DNA technology licenses to strengthen its DNA synthesis offerings and meet rising demand in the global gene cloning services market.