Neoantigen Cancer Vaccine Market Size, Share & Trends Analysis Report By Product (Personalised neo-antigen vaccine, Off-the-shelf neoantigen vaccine), By Neoantigen Type (Synthetic Long Peptide, Nucleic acid, Dendritic cell, Tumour cell), By Route of Administration (Intravenous, Intramuscular, Transdermal, Others), By Cell (Autologous, Allogenic), By Technology (RNA Sequencing, Whole Genome Sequencing, HLA Typing), By Delivery Mechanism (Liposomes, Virosomes, Gene gun, Electroporation, Others), By Application (Lung, Melanoma, Gastrointestinal, Brain cancer, Others) and By Region(North America, Europe, APAC, Middle East and Africa, LATAM) Forecasts, 2022-2030

Market Overview

Having the North American region as its most dominant market, the global neoantigen cancer vaccine market size is projected to reach USD 1.38 billion by 2030 at a CAGR of 76% from 2022 to 2030. Neoantigens that arise from cancer-specific mutations are an additional class of antigens that are desirable for therapeutic cancer vaccines. Vaccination against tumour-specific neoantigens reduces the possibility of inducing central and peripheral tolerance, as well as the risk of autoimmunity. Recent preclinical and early-phase clinical studies have demonstrated that cancer vaccines based on neoantigens have significant therapeutic potential.

Cancer vaccines employ weakened or killed viruses, bacteria, or other infection-causing agents to elicit an immune response in the body. These vaccines are intended to have a similar effect, in which the immune system will recognise, attack, and destroy cancer cells. They identify cancer cells as foreign and consequently prime the immune system to attack them. Vaccines against cancer are one way to utilise the immune system to combat cancer.

Market Dynamics

Drivers for the Neoantigen Cancer Vaccine Market

• Huge Investments Drive the Market

The growth of the market for Neoantigen cancer vaccines is primarily attributable to rapid technological advancements and improvements in the healthcare industry's infrastructure. In addition to this, the increasing investments by governments and other healthcare providers are expected to create opportunities for the global neoantigen cancer vaccine market over the next few years.

• Rising Numbers of Cancer Cases

Nowadays, sedentary lifestyles, unhealthy diets, and at times even some sorts of addiction are catering to a rise in numbers of cancer cases. This drives the market for cancer treatment and the Neoantigen Cancer Vaccines. With new research and development now, it can be assured that Cancer can be prevented as well as cured.Moreover, the demand for oncology pharmaceuticals and, it appears, the global Neoantigen Cancer Vaccine market are being driven by increased awareness of particular & effective cancer management treatments worldwide. The pharmaceutical industry has made significant investments in R&D operations to meet the latent and present demand for Neoantigen Cancer Vaccines due to the growing emphasis on individualized cancer therapy and the increasing financial burden associated with cancer treatment procedures.

• Personalised Medicines

As each person’s health conditions are different, and each body’s responses to medicine are different, with the increasing awareness, the adoption of Personalized Medicine to Tailor Patient's Treatment on an Individual Level has increased. This boosts the market for neoantigen cancer vaccine.Personalized cancer vaccines are a revolutionary formulation that calls for identifying the proper antigens in a specific patient before vaccine creation. Due to their excellent specificity and targetability for each disease, tailored vaccinations have recently attracted the most interest from academic institutions, pharmaceutical corporations, and researchers. Because the revolutionary customized cancer vaccine is created based on each person's unique genetic profile, it can overcome the drawback of traditional vaccines, which were effective in just a small subpopulation. Additionally, it lowers the price and likelihood that medications would fail in treating cancer patients. This boosts the market for a neoantigen cancer vaccine.

• Increasing Strategic Partnerships among Major Market Players to Drive Market Growth

The market is characterized by a significant focus on introducing novel vaccines by industry companies like Merck & Co., Inc., GSK plc, and others. However, a sizable market gap is feared due to a lack of product approvals and an imbalance of therapeutic indications in the pipeline for new vaccines. Additionally, small and mid-size biotech businesses and academic institutions working to develop novel cancer vaccines are having trouble finding funding and investments. Therefore, new business structures that encourage collaboration are being adopted so that these businesses may access international markets and provide the market with cutting-edge new items.

Restraints for the Neoantigen Cancer Vaccine Market

• Quite A Costly Process

Although the adoption of personalised medicines acts as a boon for the market, this is quite an expensive process. Moreover, the research & development in this process and its setup also require more considerable investments. This requirement of high capital is restricting the growth of the neoantigen cancer vaccine market.

Opportunities for the Neoantigen Cancer Vaccine Market

• Research And Development Are Predicted To Drive The Market Further

The new research and development are creating a lot of things for the market like reducing treatment gaps, reducing turnaround time and cost etc. This may boost the growth of the market in the near future. Also, the partnership and collaboration between various healthcare stakeholders are creating room for further research and development, which is predicted to drive the market in future.

• Rapid innovation in the healthcare sector

Rapid technological and infrastructure advancements in the healthcare sector are another essential aspect projected to support the growth of the neoantigen cancer vaccine market globally in the upcoming year's increased investments by governing authorities and healthcare providers.

Regional Analysis

Due to the rising prevalence and incidence of lung cancer, melanoma, gastrointestinal, pancreatic cancer, and other solid tumour indications, North America is anticipated to be the leading regional market for neoantigen cancer vaccines over the forecast period. Countries like the United States of America are enriched with good healthcare infrastructure, and they are also investing massive amounts in research and development making them the most dominant regions in the global neoantigen cancer vaccine market.

Due to the increased prevalence and incidence of cancer cases, including lung cancer, melanoma, gastrointestinal, pancreatic, and other solid tumor indications, the Asia Pacific neoantigen cancer vaccine market is anticipated to be the leading region throughout the forecast period.

Segmental Analysis

The global neoantigen cancer vaccine market is segmented on the basis of product, neoantigen type, administration route, cell, technology, delivery mechanism, application, region, and company. The market can be segmented by route of administration into intravenous, intramuscular, transdermal, and other segments. The intravenous segment is anticipated to dominate the market, while the intramuscular segment is projected to grow at the fastest rate during the forecast period. This growth can be attributed to rapid response and the fact that drug dosage can be easily controlled. In addition, intramuscular injections may be used instead of intravenous injections for drugs that cause vein irritation when administered intravenously. This is anticipated to result in substantial growth of the intramuscular route of the administration segment over the next several years.

The application segment is subdivided further into lung, melanoma, digestive, and brain cancers, among others. As the neoantigen-based immunotherapy of OSE Immunotherapeutic, which is in development for the Tedopi (OSE2101) neoantigen cancer vaccine, is expected to launch in 2022, lung cancer will dominate the market during the forecast period. Tedopi (OSE2101) is used to treat patients with HLA-A2+ Non-small cell lung cancer (NSCLC). Currently, the vaccine is in clinical development phase III.

Impact of covid-19

Covid-19 had some profound adverse impacts on the global advanced ceramics market.

COVID-19 spread across the world from China, making the whole world stand still and to a complete lockdown situation. Covid-19 is an infectious disease that was caused by a newly discovered coronavirus. During the time, the fatality rate among the population above 40 was also high globally. The disease causes severe illness for people suffering from medical conditions like diabetes, cardiovascular disease, chronic respiratory disease, etc.

Considering the situation during that time, it was declared a pandemic which led to numerous countries, including the major economies like China, the United States, India, and others, implementing lockdowns which adversely affected the global economy.

In the first two quarters of 2020, the economic and industrial operations temporarily halted. Almost every manufacturing unit where advanced ceramics is used, such as electrical and electronics, transportation, industrial, chemical, and other End-user Industries (except medical), reduced their manufacturing capacities due to the lack of workers. The lockdown implemented put a halt to global supply chains. This resulted in repercussions in terms of both production and demand for advanced ceramics.

Market Recovery Timeline and Challenges

With time the lockdowns were uplifted, and relaxation was made to the public. Gradually, the economy picked up the pace and started its operations, bringing the demand in the global advanced ceramics market and increasing among various industries. As the situation improved during the initial months of 2021, the economies also strengthened their fiscal policies and initiated their development process; the end-user industries began their activities, bringing the overall ceramics market back on track.

Recent Developments

• In December 2022, First Patient Dosed with Anti-PD1 Monoclonal Antibody OSE-279 in a Phase 1/2 Clinical Trial in Advanced Solid Tumors or Lymphomas, According to OSE Immunotherapeutics.
• In December 2022, At the American Society of Hematology (ASH) Annual Meeting 2022, OSE Immunotherapeutics will present the most recent preclinical efficacy data on its anti-IL-7 receptor antagonist OSE-127 in acute lymphoblastic leukemia.
• In January 2023, To strengthen its leading position in AI-powered drug discovery, design, and development, BioNTech will acquire InstaDeep.
• In January 2023, Up to 10,000 Patients Will Receive Personalized mRNA Cancer Immunotherapies From BioNTech By 2030, the company said in an announcement with the U.K. government.
• In February 2023, the European Commission expanded Roche's Hemlibra label to encompass Europeans with moderate hemophilia A.