Home Speciality Chemicals Ortho Phthalaldehyde Market Size, Trends, Growth, Share, Forecast to 2031

Ortho Phthalaldehyde Market

Ortho Phthalaldehyde Market Size, Share & Trends Analysis Report By End-User (Organic Synthesis, Isomeric Han LT Hides in Winemaking, Testing, Polymerization, Disinfection, Biochemistry, Others), By Applications (Amino Acids and Detection, Quantization of High-Pressure Liquid Chromatography) and By Region(North America, Europe, APAC, Middle East and Africa, LATAM) Forecasts, 2023-2031

Report Code: SRSC54777DR
Study Period 2019-2031 CAGR 5.23%
Historical Period 2019-2021 Forecast Period 2023-2031
Base Year 2022 Base Year Market Size USD 5.67 Billion
Forecast Year 2031 Forecast Year Market Size USD 8.53 Billion
Largest Market North America Fastest Growing Market Asia Pacific
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Market Overview

The global ortho phthalaldehyde market size was valued at USD 5.67 billion in 2022. It is projected to reach USD 8.53 billion by 2031, growing at a CAGR of 5.23% during the forecast period (2023-2031).

Highlights

  • Disinfection dominates the end-user segment.
  • Amino acids and detection dominate the application segment.
  • North America is the most significant shareholder in the global market.

OPA is an abbreviation for ortho phthalaldehyde. It is a pale yellow solid substance known as the fundamental building block of pharmaceutical compounds. Ortho phthalaldehyde crystals, also known as formaldehyde derivation reagents, are fluorescent derivation reagents used for various microbicidal activities. It has excellent material compatibility and a barely perceptible odor, so no exposure monitoring is required. Ortho phthalaldehyde is widely used in the medical field as a substitute for glutaraldehyde, a sensitizer. It is also highly susceptible to several anti-mycobactericidal activities at low concentrations. It is also a premium disinfection solution with FDA approval and has no detrimental effects on the mucosa, eyes, or respiratory system. However, using these compounds in a well-ventilated area and keeping containers closed is recommended.

Market Dynamics

Global Ortho Phthalaldehyde Market Drivers:

Rising Prevalence of Hospital-Acquired Infections (HAIs)

The market is anticipated to grow as hospital-acquired infections (HAIs) are becoming more common. The Centres for Disease Control and Prevention (CDC) estimates that HAIs account for about 687,000 illnesses and 72,000 fatalities each year in the United States, resulting in expenses in the billions of dollars. The prevalence of catheter-associated urinary tract infections (UTIs), central line-associated bloodstream infections (CLABSIs), ventilator-associated pneumonia (VAP), and surgical site infections are monitored by the CDC and reported. Infections linked to devices include those linked to central lines, such as catheter-related bloodstream infections, urinary tract infections linked to catheters, pneumonia linked to ventilators, and infections linked to surgical sites.

Growing Scope of Innovation to Manufacture Efficient and Safe Chemicals

Research and industry collaborations are advancing the development of more effective and secure chemicals in the rapidly expanding field of innovation in chemical manufacturing. The American Chemistry Council funds initiatives to encourage innovation in chemical safety assessment while chemical engineers plan, design, build, and operate production facilities safely at ever-increasing scales and efficiency. Ortho Phthalaldehyde is another chemical substance employed in hospitals, labs, and other industrial settings as a sterilant and disinfectant. The disinfectants and equipment sterilization markets primarily drive the market. The FDA has given the green light for the new chemical sterilant ortho-phthalaldehyde (OPA). The CDC offers details on the characteristics of chemical disinfectants, such as Ortho Phthalaldehyde. Such factors drive market growth over the forecast period.

Global Ortho Phthalaldehyde Market Restraint:

High Raw Material Cost and Regulatory Difficulties

Ortho phthalaldehyde is employed in healthcare settings as a sterilant and disinfectant. The chemical is a reagent in analyzing amino acids and a component in synthesizing heterocyclic compounds. Still, it is only occasionally available, driving up the price of raw materials. Ortho Phthalaldehyde aerosols' toxicity results in regulatory challenges because handling the substance necessitates protective precautions.

Furthermore, the FDA has particular guidelines for reprocessing reusable medical equipment and using Ortho Phthalaldehyde as a sterilant or disinfectant. For instance, the formulations approved by the FDA and on the market contain 2.4% glutaraldehyde, 0.55% ortho phthalaldehyde (OPA), and 0.95%. Ortho Phthalaldehyde (OPA) safety experts advise health and safety officials to maintain increased preventative measures. The National Institute has started a two-year, multihospital research for Occupational Safety and Health (NIOSH) to investigate potential OPA-related risks.

Global Ortho Phthalaldehyde Market Opportunities:

Technological Advancements

The market for ortho phthalaldehyde is primarily driven by the equipment disinfectants and sterilization industry. Ortho Phthalaldehyde is also being used increasingly in evaluating histamine and protein modification. Ortho-phthalaldehyde (OPA) is a high-level disinfectant approved by the FDA in October 1999 and is used to sterilize medical instruments sensitive to heat. In addition, OPA is seen as a safer substitute for glutaraldehyde. It has been discovered that OPA has numerous biochemical targets in its impact on bacteria. Protein modification and histamine testing use ortho phthalaldehyde more and more frequently, driving market growth over the forecast period.

Regional Analysis

Based on regions, the global ortho phthalaldehydes market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

North America Dominates the Global Market

North America is the most significant global ortho phthalaldehydes market shareholder and is estimated to exhibit a CAGR of 5.1% during the forecast period. In the next years, North America will likely hold the top spot in the global ortho phthalaldehyde market due to the rising preference for ortho phthalaldehyde over glutaraldehyde in various applications, including high-level disinfection. Its stability across a broad pH range and lack of activation may contribute to its rising popularity. However, the government is encouraging the use of recyclable and reusable materials in the area to promote sustainable development, which is projected to boost the expansion of the regional market, given that ortho phthalaldehyde solution can be used again after about 14 days. Additionally, hospital waste sterilization, disinfection, and control will become increasingly important due to the region's growing number of hospitals and clinics and the rising prevalence of several infectious diseases.

Asia-Pacific is expected to grow significantly over the forecast period. The region's need for ortho phthalaldehyde compounds will rise due to this growth in demand. The Asia-Pacific market is anticipated to grow significantly due to the growing demand for healthcare services, public awareness of the importance of infection prevention, and investments in medical infrastructure. In order to stop the spread of infections, ortho phthalaldehyde (OPA) is frequently used as a disinfectant and sterilizer in healthcare facilities. OPA's popularity as a sterilant is fueled by the rising number of surgeries and other medical procedures carried out globally. Additionally, HAIs are a major cause of morbidity and mortality worldwide, and it is essential to effectively disinfect medical surfaces and equipment to stop the spread of these infections. OPA is a popular choice for healthcare facilities to prevent HAIs because of its well-known broad-spectrum antimicrobial activity and high efficacy against various microorganisms.

Report Scope

Report Metric Details
Segmentations
By End-User
  1. Organic Synthesis
  2. Isomeric Han LT Hides in Winemaking
  3. Testing
  4. Polymerization
  5. Disinfection
  6. Biochemistry
  7. Others
By Applications
  1. Amino Acids and Detection
  2. Quantization of High-Pressure Liquid Chromatography
Company Profiles MP Biomedicals LLC Sigma-Aldrich Co. LLC TCI America Parchem fine & specialty chemicals DPX Fine Chemicals Thermo Fisher Scientific Inc. Merck Millipore Corporation Alfa Aesar A Johnson Matthey Company AK Scientific Inc
Geographies Covered
North America U.S. Canada
Europe U.K. Germany France Spain Italy Russia Nordic Benelux Rest of Europe
APAC China Korea Japan India Australia Taiwan South East Asia Rest of Asia-Pacific
Middle East and Africa UAE Turkey Saudi Arabia South Africa Egypt Nigeria Rest of MEA
LATAM Brazil Mexico Argentina Chile Colombia Rest of LATAM
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, Environment & Regulatory Landscape and Trends
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Segmental Analysis

The global ortho phthalaldehyde market is segmented into end-user and applications.

Based on the end-user, the global market is bifurcated into organic synthesis, isomeric Han LT hides in winemaking, testing, polymerization, disinfection, biochemistry, and others.

The disinfection segment owns the highest market share and is expected to grow at a CAGR of 5.02% over the forecast period. Ortho-phthalaldehyde (OPA) is a high-level disinfectant that works quickly and is efficient against a variety of microorganisms, including coat-defective spores, Bacillus subtilis spores, and mycobacteria that are resistant to glutaraldehyde. It is a potential substitute for glutaraldehyde, a volatile respiratory irritant with an unpleasant odor. In addition, 1,2-benzenedicarboxaldehyde (OPA) is a transparent, pale blue liquid with a pH of 7.5 and contains 0.55%. It is a high-level disinfectant with a quick action time of 12 minutes when used at room temperature. However, the equipment needed to create the product may be pricey because it is necessary to carefully control variables like pH, current, and redox potential.

The chemical ortho-phthalaldehyde (OPA) is used in various fields, including analytical and organic chemistry. One of the dialdehydes most frequently utilized in fluorometric techniques for analyzing amino acids and biogenic amines is OPA. In order to label oligodeoxynucleotides (DNA) for bioconjugation with native proteins via a condensation reaction, OPA has been developed and synthesized. Additionally, OPA has been functionalized to create a water-soluble copolymer that can be quickly, chemoselectively, and successfully conjugated with native proteins when used in a physiological setting.

Based on application, the global market is segmented into amino acids and detection and quantization of ortho phthalaldehyde.

The amino acids and detection segment dominates the global market and is expected to exhibit a CAGR of 4.98% over the forecast period. There are various benefits to using ortho-phthalaldehyde (OPA) to identify amino acids. OPA enhances sensitivity with fluorescence detection and allows the separation of amino acid derivatives on typical reversed-phase columns. In high-performance liquid chromatography (HPLC), OPA can be employed as a pre-or post-column detection reagent for amino acid analysis. HPLC, which has significantly improved speed and sensitivity in amino acid analyses, is suited to using OPA and subsequent fluorimetric detection.

In high-pressure liquid chromatography (HPLC), amino acids are quantified using ortho-phthalaldehyde (OPA). It is well known that OPA can be used to derivatize amino acids, allowing for the separation of the derivatives on typical reversed-phase columns and enhancing sensitivity with fluorescence detection. Compared to other hydrazines, the reaction of OPA with amino acids offers several benefits, such as the production of a single product, which simplifies quantitative measurement and is straightforward, quick, and accomplished in a water matrix.

Market Size By End-User

Market Size By End-User
  • Organic Synthesis
  • Isomeric Han LT Hides in Winemaking
  • Testing
  • Polymerization
  • Disinfection
  • Biochemistry
  • Others
  • Recent Developments

    • January 2023- The Binding Site Group ("The Binding Site"), a global leader in specialty diagnostics, was acquired by Thermo Fisher Scientific Inc., the world leader in providing science services, from a shareholder group led by European private equity firm Nordic Capital in an all-cash deal valued at EUR 2.3 billion, or USD 2.8 billion at the current exchange rate.
    • March 2022- The third generation of Automated Nucleic Acid Purification, the MPure-32, was released by MP Biomedicals.

    Top Key Players

    Ortho Phthalaldehyde Market Share of Key Players

    Ortho Phthalaldehyde Market Share of Key Players
    MP Biomedicals LLC Sigma-Aldrich Co. LLC TCI America Parchem fine & specialty chemicals DPX Fine Chemicals Thermo Fisher Scientific Inc. Merck Millipore Corporation Alfa Aesar A Johnson Matthey Company AK Scientific Inc Others

    Frequently Asked Questions (FAQs)

    What is the market size of Ortho Phthalaldehyde?
    The global Ortho Phthalaldehyde market size was valued at USD 5.67 billion in 2022.
    During the forecast period, the Ortho Phthalaldehyde market is grown at a CAGR of 5.23 % in North America.
    The amino acids and detection market sector is expected to dominate over the forecast period.
    MP Biomedicals LLC, Sigma-Aldrich Co. LLC, TCI America, Parchem fine & specialty chemicals, DPX Fine Chemicals, Thermo Fisher Scientific Inc., Merck Millipore Corporation, Alfa Aesar, A Johnson Matthey Company, AK Scientific Inc, and Others are the prominent players in the Ortho Phthalaldehyde market.
    Technological Advancement is one of the key trends in the Ortho Phthalaldehyde market.


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