01 Growing Organ Transplant Activity The transplantation market is witnessing increasing activity as healthcare systems work to expand access to lifesaving organ and tissue procedures. According to WHO data, 172,397 solid organ transplants were recorded globally in 2024, representing a 9.5% increase from 2022. However, transplantation activity still meets less than 10% of global needs, highlighting the significant gap between organ demand and availability. For instance, in June 2026, the WHO released a draft Global Strategy on Donation and Transplantation aimed at improving organ availability, strengthening healthcare systems, and expanding equitable access to transplantation worldwide.
02 Advances in Xenotransplantation Xenotransplantation is emerging as a potential solution to the shortage of human donor organs. Researchers are using genetic engineering and improved immunosuppression approaches to investigate whether organs from genetically modified animals can be safely transplanted into humans. The FDA continues to develop regulatory guidance for xenotransplantation as research progresses. For instance, in 2025, the FDA maintained dedicated xenotransplantation guidance covering genetically modified animal organs, tissues, and cells intended for human transplantation.
May 2026 TransMedics expanded its Organ Care System (OCS) platform with new clinical capabilities and broader commercial deployment to improve organ preservation and transplantation outcomes.
March 2026 CareDx launched enhanced transplant monitoring solutions featuring advanced molecular diagnostics to improve post-transplant surveillance and personalized patient management.
October 2025 XVIVO Perfusion expanded its organ preservation portfolio by introducing upgraded perfusion technologies designed to improve donor organ viability and transplant success rates.
June 2025 Thermo Fisher Scientific expanded its transplant diagnostics portfolio with new HLA typing and compatibility testing solutions to support faster and more accurate transplant decision-making.