The global animal model market size was valued at USD 2.91 billion in 2025 and is projected to grow from USD 3.15 billion in 2026 to USD 6 billion by 2034 at a CAGR of 8.36% during the forecast period 2026–2034.
An animal model is an animal used for biological and pathological research and testing. Animal models are used because of the human body and their functional similarities. These models are used to study the development and advancement of various diseases and test new treatment methods before conducting human trials. However, animal welfare guidelines are to be followed while animal models are used for experiments. Rats, mice, guinea pigs, and rabbits are among the animals utilized as animal models.
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Three viral outbreaks have occurred in the last two decades: SARS-CoV in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019. SARS-CoV-2 is far worse than SARS-CoV in 2002 and has spread to 213 countries, impacting millions of people. The 2019 appearance of COVID-19 prompted the use of animal models to understand its pathogenesis and create viable treatments. Aside from COVID-19 research, the mice model is ideal for hepatitis C virus (HCV), Zika virus, cytomegalovirus (CMV), and hepatitis B virus (HBV). Johns Hopkins University estimates that COVID-19 has killed 3.7 million individuals. Mouse models are frequently used in viral research because of their ease of use and high repeatability. As a result, animal models in virology and infectious diseases encourage market growth.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a time-saving, easy-to-perform technique as it enables quick, cost-effective animal model creation. It enables the development of mutant mouse models that were previously impossible to create using traditional methods. This method has resulted in developing knock-in and knock-out animal models for drug testing. It allows quick generation of mice with single point mutations or conditional alleles, mimicking human patients in weeks. This technology is the primary tool for studying gene function and genetic modification in vivo.
Implementing animal protection and welfare legislation has restricted animal use as many nations forbid animal testing in cosmetics. Australia prohibited animal test data for cosmetics in 2019. In 2018, Minas Gerais banned cosmetic animal experiments, and Sri Lanka passed an animal protection law. National Institutes of Health (NIH)-funded institutes must follow Public Health Service (PHS) guidelines on laboratory animal usage (ILAR). Research institutions should seek the Association for Assessment & Accreditation of Laboratory Animal Care International (AAALAC) to enhance financing. Complying with mandatory rules for animal models may be complex and time-consuming, which may limit the market expansion.
Unexplored, expanding territories, improved healthcare infrastructure, and rising pharmaceutical and medical device sectors are expected to drive expansion in the animal model industry. Rising demand for advanced manufacturing technologies and government expenditures to modernize healthcare facilities are boosting the healthcare industry in emerging nations. Patent expiration and higher demand drive growth in India, China, and Japan. Asian nations have improved pharmacology via animal studies and rich resources, which is expected to boost the market.
North America is the most significant global animal model market shareholder and is expected to grow at a CAGR of 6.2% during the forecast period. The US held the highest portion of North America's revenue. Prominent enterprises such as Horizon Discovery, The Jackson Laboratory, and Crown Bioscience Inc are a few market players dominating North America's animal model market. Growth in the industry is driven by increased government and non-government financing for pharmacological development, viral infections, and animal models. The growing use of animal models in biomedical, neurological, genetic, toxicological, cancer, physiological, and research contributes to North America's regional dominance.
Europe is predicted to grow at a CAGR of 5.5%, generating USD 712 million during the forecast period. Due to the rising demand and establishment of companies like GenOway S.A., EUROFINS SCIENTIFIC, JANVIER LABS, and PolyGene, the European animal model market is expected to rise. The European Union's measures to improve animal welfare and usage of animal models in R&D help the industry. Novel pharmaceutical research, animal testing to ensure drug safety, pharma and biotech R&D, and preclinical trials support Europe's growth. The desire for precision medicine, understanding diseases such as cancer, cardiovascular diseases, and more, and using CRISPR technology are other market drivers.
Asia-Pacific is predicted to have the fastest market growth resulting from government support, efforts, and investment in medication R&D employing animal models. The availability of modern healthcare systems, the significant increase in demand for cutting-edge healthcare facilities, the rise in preclinical activities by CROs and pharmaceutical companies in the region, the rise in mouse clinical trials (MCTs) for further predicting results, the ongoing improvements in animal models, the availability of modern healthcare systems, and more are significant drivers of market expansion.
Latin America, the Middle East and Africa are expanding markets predicted to present attractive development possibilities for significant players due to an increase in the target population, increased use of animal models in virology and infectious illnesses, and improved healthcare infrastructure. Increased incidence of chronic illnesses and government engagement in research institutions in LAMEA drive the usage of animal models, propelling market expansion.
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Healthcare Lead
Debashree Bora is a Healthcare Lead with over 7 years of industry experience, specializing in Healthcare IT. She provides comprehensive market insights on digital health, electronic medical records, telehealth, and healthcare analytics. Debashree’s research supports organizations in adopting technology-driven healthcare solutions, improving patient care, and achieving operational efficiency in a rapidly transforming healthcare ecosystem.
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