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Capillary Electrophoresis Market

Capillary Electrophoresis Market: Information by Product Type (Instrument, Consumables), Mode (Capillary Zone), Application (Nucleic Acid Analysis), and Region — Forecast till 2030

Published At : 05 Aug, 2022
Updated At : 07 Aug, 2022
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Market Snapshot
Base Year:
2021
Study Period:
2020-2030
CAGR:
5.6 %
Fastest Growing Market:
Asia Pacific
Largest Market:
North America

The global capillary electrophoresis market size was valued at USD 39 million in 2021. It is expected to reach USD 557.6 million by 2030, growing at a CAGR of 5.6% during the forecast period (2022–2030). Diagnostics are an integral component of medical decision-making and aid in acquiring information for a vast array of treatment dissemination, highlighting their significance in healthcare. Capillary electrophoresis is essential to the precision medicine approach, as it ensures the safe and efficient administration of targeted therapeutics. The majority of market participants in the global capillary electrophoresis industry offer products in kits and reagents, instruments, and software. In addition, many diagnostics and pharmaceutical companies collaborate to develop various capillary electrophoresis modes for applications in various disease indications to facilitate efficient diagnosis, treatment selection, dosage selection, and treatment monitoring.

Capillary electrophoresis has become an integral part of routine healthcare by providing laboratory tests in infectious disease and genetics and an increasing number of oncology tests. The massively parallel methods that have now surpassed capillary electrophoresis enable inexpensive sequencing of entire genomes. The majority of microorganisms are now categorized based on their sequence rather than their phenotype due to extensive sequencing procedures.

The advanced classes of biomarkers, such as microRNAs and long non-coding RNAs, demonstrate substantial disease correlations. An example of a genetic diagnosis is the consistent association of a patient's sequence with a disease. Likewise, cancer is caused by the extensive variation in the genome sequence. Typically, these variations accompany multiple copy number and sequence changes spanning the entire genome. Several of these variants target molecular pathways that can be inhibited or stimulated by drugs that affect tumor growth.

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Market Dynamics

Market Driving Factors

Strategic Initiatives by Major Players to a Positive Impact on Global Market

The global capillary electrophoresis market is receiving more attention due to the strategic initiatives implemented by newly emerging companies and established market juggernauts. The most successful companies on the market are actively expanding their operations through product launches, mergers and acquisitions, and other strategic moves. The introduction of new products is causing existing players in the market to engage in a more intense level of competition to maintain their position. Capillary electrophoresis industry participants have demonstrated consistent competition by developing a diverse range of products and a wide range of alternatives. It is anticipated that the subsequent trend of strategic initiatives will continue to be prevalent in the global market for capillary electrophoresis.

Increasing Use of Personalized Medicine and Sequencing in Researching Fields to Aid Growth

Next-generation sequencing (NGS), also known as deep sequencing, is utilized for DNA and RNA analysis detection. The emergence of sequencing technologies, specifically next-generation sequencing (NGS), has altered diagnosing genetic disorders, allowing physicians to understand the diseases better. Sequencing permits a more detailed analysis and resolution of the essential nature of the transcriptome. High-throughput next-generation sequencing is being reformed for RNA analysis. The most recent advancement in RNA sequencing has substantially affected sample preparation and sequencing. This is useful for describing the transcriptome and comprehending the potential for demonstrating distinct physiological and pathological criteria.

Clinical applications of capillary electrophoresis in precision medicine include the analysis of nucleic acids and proteins. The increasing prevalence of precision medicine and biologics and the patients' increasing adaptability to them has resulted in the rise of personalized treatments. Developing personalized medicine requires comprehensive knowledge of the disease's biological mechanism. Through cellular characterization, nucleic acid analysis enables the discovery of biomarkers and the development of target-based therapeutics. This information can create personalized treatments, thereby reducing treatment costs. With increasing awareness of its efficacy, the nucleic acid analysis method of diagnosing inherited diseases is gaining widespread acceptance.

Market Restraining Factors

Lack of Capital and Infrastructure to Hinder Market Growth

The accelerating pace of technological development necessitates highly developed laboratories and institutions to conduct full-time interdisciplinary research. Due to the current funding scenario, academic research institutions lack the necessary funds to establish the infrastructure required for capillary electrophoresis and its subsequent comprehensive interpretation. For example, high levels of automation are required to support complex genomic testing procedures. The availability of the required expertise for high-complexity testing facilities has also been identified as a limitation. Also, high-skilled personnel is hard to find because they need a wide range of skill sets to operate today's most advanced platforms. In addition, academic institutions' salary restrictions prevent the availability of these specialized high-complexity testing centers.

Despite the high opportunity for expansion in various emerging and major markets, the high investment and infrastructure requirements are the primary factors restricting the expansion. Consequently, the amount of capital required depends on the size and capabilities of the laboratory established. Despite the enormous growth potential of the global capillary electrophoresis market, the high capital investment requirement restricts the market's ability to expand globally, creating a barrier to this goal.

Key Market Opportunities

Growing Support from the Government and Private Sectors to Spur Market Opportunities

Numerous nations are investing in national programs for population sequencing. Government agencies have sequenced millions of genomes to advance research and find better ways to diagnose and treat cancer and rare disorders. The large genome is sequenced using capillary electrophoresis to identify and track genetic variation more efficiently and precisely. The Bio-Analysis Centre provided deltaDOT to its clients to expand capillary electrophoresis techniques in contract research, training, and research development to aid in identifying and quantifying a vast array of analytes.

Due to extensive genomics research for clinical decision-making, the industry is developing complex equipment to complement their sequencing instruments and aid professionals in generating actionable insights. These advances have separated genomics-based applications for diagnosing complex disorders, from rare diseases to infectious diseases such as COVID-19. Given the escalating rate of progress in genomics, it is essential to recognize the field's dynamism. Newer technologies are replacing them because they enable a deeper comprehension of the complexities of genome behavior in healthy and diseased individuals.

 

Segmental Analysis

The global capillary electrophoresis market is segmented by Product Type, Mode, Application, and End-User.

On the Basis of Product Type

Based on product type, the global market is categorized into instruments, consumables, and software.

The consumables segment is dominating the market with the highest revenue, growing at a CAGR of 6.4% during the forecast period. An assay is a technique used in molecular biology, pharmacology, laboratory medicine, and environmental biology for qualitative or quantitative measurement of a target entity's presence, quantity, or functional activity (the analyte). The analyte may be an organic sample, a cell within an organism, a drug, or a biochemical compound. The measured substance is typically the analyte, the assay's target or measure. Typically, the assay measures and expresses an intensive property of the analyte in the appropriate measurement units (e.g., molarity, density, etc.).

On the Basis of Mode

Based on mode, the global market typically includes capillary zone electrophoresis, capillary gel electrophoresis, and capillary electrochromatography.

The capillary gel electrophoresis dominates the market, growing at a CAGR of 6.09% during the forecast period. Although capillary gel electrophoresis is at the forefront of developing advanced technology-based products, capillary zone electrophoresis has a wide range of diagnostic applications. Additionally, it is anticipated that capillary zone electrophoresis and capillary gel electrophoresis will actively incorporate diagnostics due to a shift in emphasis toward next-generation sequencing and an increase in the prevalence of infectious diseases and various types of cancer. Compared to other modes, capillary electrochromatography contributes significantly to expanding the global capillary electrophoresis market.

On the Basis of Application

Based on application, the global market includes nucleic acid and protein analysis.

The nucleic acid analysis electrophoresis dominates the market, growing at a CAGR of 6.09% during the forecast period. Nucleic acid analysis generally involves isolating and characterizing the target DNA or RNA sample. Analyses of nucleic acids include purification techniques, hybridization, in situ hybridization, and DNA sequencing. The primary application of capillary electrophoresis is nucleic acid analysis, which includes genotyping, gene expression analysis, epigenetic analysis, and microbiome research.

On the Basis of End-Users

Based on end-users, the global market typically includes academic and research institutions, clinical laboratories, pharmaceutical, and biotechnology companies.

The academic and research institutions are dominating the market and are expected to reach USD 215 million during the forecast period. In addition, academic and research institutions and clinical laboratories are anticipated to actively incorporate diagnostics due to a shift in emphasis toward next-generation sequencing and a rise in the prevalence of infectious diseases and various cancers. Considering other pharmaceutical and biotechnology companies as capillary electrophoresis market end-users is crucial to the market's expansion.

 

Regional Analysis

The global capillary electrophoresis market is segmented into different regions, namely, North America, Europe, Asia-Pacific, Latin America, and Rest-of-the-World.

Capillary Electrophoresis Market Regional Analysis

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North America is dominating the global capillary electrophoresis market and is expected to reach USD 227.78 million in 2030, growing at a CAGR of 6.05% during the forecast period. Due to the substantial funding and the country's concentration of university-affiliated pharmaceutical research centers, the region remains the primary hub for pharmaceutical development and outsourcing. In addition, the favorable regulatory environment and improved availability of logistics and quality have resulted in market expansion. The United States and Canada dominate the North American capillary electrophoresis market. The U.S. region dominated the regional segment due to many market participants already present in the country and significant regional investments. In addition, the country's research and development expenditures are substantial, encouraging the expansion of manufacturing facilities in the region.

 

Competitive Players

  • QIAGEN
  • Thermo Fisher Scientific Inc.
  • Agilent Technologies Inc.
  • Bio-Rad Laboratories Inc.
  • Danaher
  • Bio-Techne
  • PerkinElmer Inc.
  • Merck KGaA
  • Shimadzu Corporation
  • Hitachi Ltd.
  • Teledyne Technologies Incorporated
  • Helena Laboratories
  • BiOptic Inc.
  • LABGENE Scientific SA
  • Helena Laboratories
  • Promega Corporation
  • BiOptic Inc.
  • LABGENE Scientific SA.

 

Recent Developments

  • May 2022- QIAGEN continued to update its automation solutions with the launch of the high-sensitive capillary electrophoresis instrument QIAxcel Connect. QIAGEN announced the launch of QIAxcel Connect, a high-speed, high-resolution, and high-sensitivity capillary electrophoresis (CE) instrument for nucleic acid analysis.
  • May 2022- QIAGEN launched therascreen EGFR Plus RGQ PCR Kit featuring C797S detection to help guide non-small cell lung cancer (NSCLC) treatment. therascreen EGFR Plus RGQ PCR Kit is a new in-vitro diagnostic test for sensitive EGFR mutation analysis that detects all known activating and resistance EGFR mutations.

 

Global Capillary Electrophoresis Market: Segmentation

By Product Type

  • Instrument
  • Consumables
  • Software

By Mode

  • Capillary zone electrophoresis
  • Capillary gel electrophoresis
  • Capillary electrochromatography

By Application

  • Nucleic acid analysis
  • Protein analysis

By End-User

  • Academic and research institutions
  • Clinical laboratories
  • Pharmaceutical and biotechnology companies

By Regions

  • North America
  • Europe
  • Asia-Pacific
  • Latin America 
  • Rest-of-the-World
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