CRISPR Gene Editing Market Size, Share & Trends Analysis Report By Product Type (CRISPR Products, CRISPR Services), By Application (Agricultural, Biomedical, Industrial, Genome Engineering, Disease Models, Functional Genomics, Others), By End User (Academic Institutes and Research Centres, Biotechnology Companies, Contract Research Organizations (CROs), Pharmaceutical and Biopharmaceutical Companies) and By Region(North America, Europe, APAC, Middle East and Africa, LATAM) Forecasts, 2024-2032

CRISPR Gene Editing Market Size & Trends

The global CRISPR gene editing market size was valued at USD 3.44 billion in 2023. It is expected to reach USD 25.28 billion in 2032, growing at a CAGR of 24.81% over the forecast period (2024-32). CRISPR-Cas9 technology revolutionized gene editing by enabling precise modifications in genetic sequences. Continuous advancements in CRISPR tools, such as Cas proteins, CRISPR-Cas systems, and delivery methods, enhance editing efficiency and specificity.

Gene editing, also known as genome editing, is a technique for altering an organism's DNA using a variety of methods. This approach allows for the replacement, addition, or removal of genetic material at spotted places in the genome. As a result, a variety of editing techniques have been created for its use in the industry. Human disorders such as cystic fibrosis, sickle cell disease, HIV infection, cancer, and others are also treated and prevented through gene editing.

Genome engineering has had a significant impact on the future of the healthcare and life science industries, as evidenced by its progress. The remarkable efficiency of the CRISPR-Cas9 method for genome editing has been established in much research, leading to considerable investments in the field of genome engineering. Prior to any clinical use, it is necessary to weigh the benefits and drawbacks of each potential variant. CRISPR gene editing technique has its limitations, and many researchers are attempting to overcome them in order to get better outcomes. Incredibly, the CRISPR gene editing technology holds enormous promise for modifying human genomes and disease conditions. However, ethical and societal problems abound.

Research organizations, pharmaceutical, and biotechnology firms, and institutions are seeking more efficient genome editing tools to increase specificity, cost-effectiveness, turnaround speed, and human errors. Genome editing methods have evolved to enable applications in industrial biotech and agricultural research. These new technologies are simple, efficient, cost-effective, multiplex, and high throughput. The increasing geriatric population, cancer cases, and genetic abnormalities will boost the demand for CRISPR gene editing.

CRISPR Gene Editing Market Growth Factors

The Market Will Grow as More Money Is Invested in Genetic Research

The growth of the CRISPR gene editing business will be fueled by increased financing for genetic research in industrialized areas like North America. Many governmental agencies in the United States invested in the creation of new materials, equipment, and processes for the benefit of the public good. Government funding helps to develop and manufacture medical discoveries for rare genetic illnesses. Funding for genomics research is provided by the National Human Genome Research Institute (NHGRI).

Genetic and biological research is carried out by the National Institutes of Health (NIH), an agency of the Department of Health and Human Services and a medical research organization in the United States. Arizona State University and Bayer College of Medicine will get USD 1.6 million from the NIH in 2021 to test human genome editing. It is expected that the CRISPR gene editing market growth will be boosted by the development of new treatments for genetic diseases.

Chronic Diseases Are Becoming More Common and More Prevalent

When it comes to chronic illnesses, one in three persons suffer from one or more. Many people's health and well-being have been adversely affected by chronic diseases. Clustered regularly interspaced short palindromic repeats (CRISPR) is the abbreviation for this technology. Using CRISPR, a gene-editing technique has become a powerful tool in recent years. Huntington's disease, muscular dystrophy, cancer, and excessive cholesterol all benefit from CRISPR. Consider, for example, the diagnosis rate for Duchenne Muscular Dystrophy in 2021 as reported by NORD - the National Organization for Rare Disorders, Inc. (DMD). Every 3,500 male babies around the world are born with the hereditary disorder known as Duchenne Muscular Dystrophy (DMD). In addition, factors like as rising disposable income, an increasing prevalence of chronic diseases, and alterations in lifestyle will all contribute to the expansion of the global market.

Market Restraints

CRISPR-Based Diagnostics Have Become More Expensive

There is a high price to pay for CRISPR-based therapies. Due to the increased time and resources required for the research and production of maximum genome editing medicines, the cost rises. In addition, a wide range of people can benefit from CRISPR gene detection and diagnostic assay kits and treatments. Patients are forced to bear the burden of these expenses. As a result, a decline in the current high price is projected in the future. For example, the first commercially accessible CRISPR-based diagnostic assay for SARS-CoV-2, comprising reverse transcription LAMP (RT-LAMP) as pre-amplification, will be available in July 2021 at USD 30.15 per response, according to Integrated DNA Technologies, Inc. The Global CRISPR Gene Editing Market growth is expected to experience slow over the next few years due to ethical concerns about genetic editings, such as safety and the high cost of gene treatments.

Market Opportunities

Developing Gene Editing Technologies Offer Tremendous Market Growth Potential

The market is divided into contract research organizations (CROs), biotechnology and pharmaceutical businesses, and research institutes according to the type of end-user they serve. In 2021, the segment consisting of biotech and pharmaceutical companies held more than 45.5 percent of the market share. The segmental expansion will be increased as a result of an increasing focus on the development of novel gene editing methods by a variety of biotechnology companies. For example, Horizon Discovery's goal was to develop a genome editing tool that utilized cutting-edge technology to produce functional genes that were both precise and effective. The company has released a number of products, one of which is the Modify-R algorithm CRISPR guide RNAs, which can edit the gene that is being targeted. Over the course of the past several years, developments in technology have made it possible for market participants to develop gene editing tools that are effective for the treatment of genetic illnesses.

Regional Insights

The Global CRISPR Gene Editing Market share is segmented by geography into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.

North America dominated the global share of the global market because of significant investments by pharmaceutical and biotech organizations, improved healthcare infrastructure, rising per capita income, early availability of approved therapies, and the presence of state-of-the-art research labs and institutions in the region. Because to the rise in rare illnesses in the United States and Canada, North America accounted for roughly 38% of the market in 2021 and is predicted to grow significantly throughout the forecast years. Approximately 7,000 uncommon diseases impact between 25 and 30 million Americans, according to the National Institutes of Health (NIH). As a result, as new gene editing tools and technologies become available, the demand for medication development to treat rare disorders grows.

Due to major advances in drug discovery analysis, an expansion in the number of research studies, the growth of the biotech industry, and other factors, the United States has risen to the top of the market.

North America is expected to have the greatest market share in 2031. The rise in government and private funding, the existence of big pharma and gene therapy businesses, and the use of CRISPR in a variety of applications are all contributing to this. Furthermore, crops treated with CRISPR-based gene editing are not deemed GMOs in the United States, which has prompted a number of agricultural companies to work on CRISPR-edited crop commercialization.

The Asia Pacific market for crispr gene editing market was valued at approximately 1.9 billion USD in 2022. An increasing number of research organizations in emerging countries will contribute to an improved industry landscape in the region. Growth in the regional sector is expected to be fueled by the major corporations' current focus on the development of gene editing technology. The market for bioscience is experiencing the most rapid expansion in the Asia Pacific region. This occurs as a result of the increased financing provided by the government to the biotechnology industry for the purpose of enhancing disease treatment. The growth of research and development efforts in China, Japan, and India will also play a role in driving regional market trends.

Due to a lack of technical understanding, the expansion of the global market will be hampered by the limited development in the biotechnology sector that has occurred in both the Middle East and Africa

Segmental Analysis

By Product Type

The market is segmented into CRISPR Products and Services. CRISPR Products are further divided into Kits and Enzymes (Vector-Based Cas9, and DNA-Free Cas9), Libraries, Design Tools, Antibodies, and Other Products (CRISPR/Cas9 plasmids, CRISPR Controls, and CRISPR RNAs). CRISPR Services are further divided into gRNA Design and Vector Construction, Cell Line and Engineering, Screening Services, and Other Services (Mediated Transcriptome Editing, and Epigenome Editing Services).

By Application

The Global CRISPR Gene Editing Industry is segmented into Agricultural, Biomedical (which include Gene Therapy, Drug Discovery, And Diagnostics), Industrial, and Other Applications such as Genetically Modified Foods (GM Foods), Biofuel, And Animal (Livestock) Breeding.

By End-User

The global market is segmented into Academic Institutes and Research Centers, Biotechnology Companies, Contract Research Organizations (CROs), and Pharmaceutical and Biopharmaceutical Companies. Biotechnology Companies and Pharmaceutical and Biopharmaceutical Companies are the most important End-User segments among all others.

Impact of covid-19

Covid-19 had some profound adverse impacts on the global advanced ceramics market.

COVID-19 spread across the world from China, making the whole world stand still and to a complete lockdown situation. Covid-19 is an infectious disease that was caused by a newly discovered coronavirus. During the time, the fatality rate among the population above 40 was also high globally. The disease causes severe illness for people suffering from medical conditions like diabetes, cardiovascular disease, chronic respiratory disease, etc.

Considering the situation during that time, it was declared a pandemic which led to numerous countries, including the major economies like China, the United States, India, and others, implementing lockdowns which adversely affected the global economy.

In the first two quarters of 2020, the economic and industrial operations temporarily halted. Almost every manufacturing unit where advanced ceramics is used, such as electrical and electronics, transportation, industrial, chemical, and other End-user Industries (except medical), reduced their manufacturing capacities due to the lack of workers. The lockdown implemented put a halt to global supply chains. This resulted in repercussions in terms of both production and demand for advanced ceramics.

Market Recovery Timeline and Challenges

With time the lockdowns were uplifted, and relaxation was made to the public. Gradually, the economy picked up the pace and started its operations, bringing the demand in the global advanced ceramics market and increasing among various industries. As the situation improved during the initial months of 2021, the economies also strengthened their fiscal policies and initiated their development process; the end-user industries began their activities, bringing the overall ceramics market back on track.

Recent Developments

• May 2024 - A clinical trial called BRILLIANCE, involving researchers from the Perelman School of Medicine at the University of Pennsylvania and CHOP, demonstrated that CRISPR-Cas9 gene editing can improve vision in children with Leber Congenital Amaurosis (LCA). This was the first time children with this form of inherited blindness received gene editing treatment, resulting in measurable improvements in sight for nearly half of the participants, including the children. The study found no significant side effects or dose-limiting toxicities.
• April 2024 - A recent study conducted by a team at Montana State University demonstrated the ability to modify RNA, which is a closely related chemical compound to DNA, using CRISPRs. The study uncovers a novel mechanism within human cells that holds promise for the treatment of a diverse range of hereditary disorders.