The global flow cytometry market had a revenue holding of USD 6,912 million in 2021. It is expected to reach USD 13,874 million by 2030, growing at a CAGR of 9.1% during the forecast period (2022–2030). Cytometry employs a vast array of cutting-edge techniques, the majority of which evaluate the molecular characteristics of cells by applying fluorescent labeling to detect specific antigens with antibodies, intracellular ions with indicator dyes, fluorescent reporter molecules such as green fluorescent protein (GFP), and DNA and RNA with nucleic acid-specific probes. The advancement of cytometry has been essential in developing the fields of biology, medicine, and technology. The most common examples of cytometry are flow and image cytometry, primarily optical techniques. However, "cytometry" can refer to any method used to extract quantitative information from individual cells. Flow cytometry is a technique that examines single cells or particles as they flow past single or several lasers in a buffered salt solution.
Flow cytometry is a laser-based method for detecting and analyzing cells' and particles' chemical and physical properties. It is frequently used to assess your body's fluids, including bone marrow and peripheral blood. A sample of cells or other particles is injected into a flow cytometer system while suspended in the liquid. A computer can analyze and process 10,000 cells in less than a minute. The global flow cytometry market is driven by the rising prevalence of viral diseases, immunodeficiency disorders, and cancer. The high demand for flow cytometry instruments is also a result of increasing research & development expenditures in biotechnology, life science, and pharmaceutical research activities. Microfluidic flow cytometry for Point-of-Care (POC) testing is one of the new and enhanced analytical instruments brought about by technological developments in flow cytometry.
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Increasing Prevalence of Target Diseases
Flow cytometry is frequently utilized to diagnose immune deficiencies and cancer. One of the elements anticipated to propel the market over the forecast period is the rising prevalence of certain disorders. Additionally, the adverse effects of chemotherapy and radiation therapy in cancer treatment have led doctors to favor autologous and allogeneic stem cell therapies more, favorably affecting the development of the flow cytometry market. The World Cancer Research Fund (WCRF) data indicated roughly 18 million new cancer cases worldwide in 2018. About 17,036,901 of which were brand-new cases. In 2018, there were approximately 437,033 newly diagnosed cases of leukemia, according to reports. Leukemia can be diagnosed and categorized using flow cytometry, making it easier to tell lymphoid from myeloid leukemia.
According to 2017 NCBI statistics, Primary Immunodeficiency Diseases (PID) ranged between 0.81 and 30.5 per 100,000 individuals. To identify and characterize immune cells, flow cytometry is deemed to be a crucial technique. Furthermore, it aids in identifying some underlying genetic flaws and confirms newly discovered ones. Organ transplantation, therefore, plays a vital role in accelerating market expansion. Flow cytometry is also employed to monitor the immune response following stem cell transplantation. Additionally, fueling demand for flow cytometry is the rise in bleed disorders. Hemophilia A and B and Von Willebrand disease are the most prevalent forms, according to NCBI statistics, which indicate that 1 in 1000 people worldwide suffers from a bleeding problem.
Since flow cytometry equipment is expensive, many emerging economies cannot afford the most cutting-edge flow cytometers. A four- to six-color and two-laser device costs close to USD 75,000 to USD 100,000, which places a significant financial strain on small- and medium-sized hospitals and diagnostic laboratories in developing economies. Attune, a two-laser, six-color instrument from Thermo Fisher Scientific, costs USD 99,000 in the United States. Thus, the high equipment cost will be anticipated to reduce the market for improved flow cytometers.
This market's prospects are anticipated due to technological advancements that improve accuracy, mobility, and cost-effectiveness. Due to its advantages over larger cytometers, such as portability and affordability, small high-throughput cytometers are anticipated to become more commonplace in the years to come. Future market growth is also expected due to advancements in fluorescent dyes and the release of bench-top cytometers. Rapid developments in multicolor flow cytometry, which has numerous applications in creating new drugs, have made it simple to analyze cells by evaluating multiple factors simultaneously. Many contract research groups have embraced these devices widely.
The deployment of flow cytometry in point-of-care diagnostics is anticipated to be aided by microfluidic tiny flow cytometry, which is considered an essential element enhancing future market growth. By serving customers in research laboratories and small auxiliary laboratories, the advent of multiplex reagents and probes for specialized applications in drug discovery & diagnostics is anticipated to open up new growth potential. The domain of flow cytometry has undergone a revolution due to digital signal processing. It enables a more realistic representation of scattered and fluorescence data processing. The degree of flexibility in data analysis has been increased due to this technology; for instance, one of the functions, fluorescence correction, can be carried out after data collection.
The global flow cytometry market is segregated into product, technology, application, end-user, and region.
Product-wise, the global flow cytometry market comprises Instruments, Reagents & Consumables, Software, Accessories, and Services.
The Instrument section will likely hold the largest market share over the forecast period, growing at a CAGR of 8.75%. Flow cytometry instruments include cell analyzers, cell sorters, sample preparation devices such as cell analysis platforms, and replaceable components such as filters, lasers, and detectors. Flow cytometry is among the optofluidic technologies. It involves cell suspension in a liquid stream passed via a laser-based electronic detection device. This market segment is anticipated to increase steadily in the future years.
The Reagents & Consumables section will hold a significant market share. This is attributable to its widespread use in flow cytometry for various applications. This segment includes dyes, beads, recombinant proteins, antibodies, and buffers for research applications in cell biology and immunology. Increasing demand for sensitive assays, fluorescent dyes, and antibodies for identifying new biomarkers while developing new vaccines and medicines is anticipated to drive sector expansion over the forecast period.
Technology-wise, the global flow cytometry market comprises Cell-based and Bead-based.
The Cell-based section is projected to grow at a CAGR of 8.9% and hold the largest market share over the forecast period. The market for cell-based flow cytometry is anticipated to grow significantly over the forecast period due to its widespread application in various scientific disciplines. In drug discovery, cell-based assays are used to evaluate the physiological properties of cells and analyze the obtained data. In addition, technical improvements, such as multiparameter flow cytometry in rare cell analysis, are anticipated to drive segment demand in the future years.
The Bead-based section will hold the second-largest market share. The development of bead-based assays for the study of infectious illnesses. Due to developments in molecular engineering and monoclonal antibody production, as well as the related benefits, such as cost-effectiveness, low sample requirement, and quick turnaround time, the demand for these assays is anticipated to increase at a healthy rate over the projection period.
Application-wise, the global flow cytometry market comprises Research, Industrial, and Clinical.
The Research section will hold the largest market share over the forecast period, growing at a CAGR of 9.2%. Flow cytometry has become an indispensable research tool for the past several decades. The rising incidence of cancer and hematologic illnesses and the demand for novel treatments for their treatment has significantly increased the demand for flow cytometry solutions for scientific research. Additionally, increased R&D expenditures in the pharmaceutical and biotechnology industries are anticipated to foster market expansion.
The Industrial section will hold the second-largest market share. Flow cytometry is utilized in food microbiology and tissue culture to monitor pathogenicity. Using conjugating antibodies, it analyzes various cell characteristics in microbial populations and identifies individual bacteria. In the field of food microbiology, flow cytometry is utilized to assess food safety. Thus, it is projected that expanding the food business in both developed and developing nations will generate profitable prospects for flow cytometry solutions.
End-user-wise, the global flow cytometry market comprises Commercial Organizations, Hospitals, Academic Institutes, and Clinical Testing Labs.
The Commercial Organization section will grow at a CAGR of 9.5% and hold the largest market share over the forecast period. This segment includes pharmaceutical & biotechnology firms, cosmetics, food & beverages, biodefense, veterinary, agriculture, and contract research organizations, which employ flow cytometry. This section includes firms that use flow cytometry platforms for industrial applications, such as the large-scale manufacturing of therapeutic proteins, monoclonal antibodies, and cell lines.
The Hospital section will hold the second-largest market share. This sector includes hospital and university laboratories that use flow cytometry for disease diagnostics and other purposes. Flow cytometry diagnoses minimally invasive illnesses, cancer, and infectious disorders. It has many clinical applications, including transplantation, tumor immunology, hematology and chemotherapy, prenatal diagnostics, sperm sorting for sex selection, and genetics.
North American Prevalence in the Global Market
Region-wise, the global flow cytometry market is analyzed across North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa.
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North America will command the market, growing at a CAGR of 8.4% over the forecast period. The US's well-established healthcare system and pharmaceutical sector have created a massive demand for flow cytometry solutions for clinical and research applications, which accounts for the region's large market share. Extensive research & development initiatives for producing vaccines and therapies for covid, as well as increased public-private funding in cancer research, have boosted the demand for flow cytometry solutions in the country, resulting in rapid market expansion. In addition, the US is the most lucrative market in the world due to its affordability and widespread adoption of innovative and advanced flow cytometry systems and solutions. Government support and financing to facilitate the development of innovative flow cytometry technologies in regional nations are also expected to generate attractive growth prospects.
Europe will likely generate USD 3,673 million by 2030, growing at a CAGR of 8.85%. The expansion of the Europe flow cytometry market is primarily attributable to the rising demand for flow cytometry products in nations with well-established biotechnology sectors, including Germany, the United Kingdom, and Italy. The increasing biotechnology sector in Spain and Russia also fosters the expansion of the Europe flow cytometry market. In addition, continual research activities conducted by European manufacturers for the creation of new and innovative flow cytometry technologies are predicted to generate attractive market growth prospects.