North America Plasmapheresis Machines Market Size & Outlook, 2025-2033

North America Plasmapheresis Machines Market Size

The North America plasmapheresis machine market size was valued at USD 868.8 million in 2024 and is projected to reach from USD 947.1 million in 2025 to USD 1,929.6 million by 2033, growing at a CAGR of 9.25% during the forecast period (2025-2033).

A plasmapheresis machine is a machine that performs plasmapheresis to extract small amounts of blood at a time. Plasmapheresis is a method of removing blood plasma from the body that entails drawing blood, separating it into plasma and cells, and then reintroducing the cells into circulation. In the therapy of autoimmune illnesses, it is done precisely to eradicate antibodies. Any technique that removes blood, filters and keeps elements of it, and then returns the blood to the body is known as pheresis or apheresis. It is possible to separate platelets, red blood cells, white blood cells, or plasma. A machine is used to remove little volumes of blood at a time during the treatment.

The components of blood can be separated in two ways:

Centrifugation: This mechanism rotates the blood, dividing it into portions based on its density.

Filtration: The blood is separated from the plasma by passing it through a filter. The equipment will discard unhealthy plasma and replace it with healthy plasma from a donor during a plasma exchange. Saline, albumin, or a combination of the two can be used to replace unhealthy plasma.

Due to a growing number of apheresis treatments and developments, a growing number of apheresis centres, and access to well-developed infrastructure, the United States is likely to lead the market in the North American area.

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Market Dynamics

Market Driving Factors

• Growing Medical Tourism

  Over the next seven years, the North American medical tourism business is expected to surpass USD 3 billion in sales, putting it in the billion-dollar club. The availability of highly experienced medical personnel and the utilization of new technologies to provide diagnosis and treatment are driving the medical tourism market in North America. The concept of medical tourism has exploded in popularity in both developed and poor countries.

• Hematologic Illnesses Are Becoming More Common

  Blood illnesses are known to be dangerous, regardless of whether they are malignant or not. Due to their great prevalence, non-cancerous blood diseases such as hemoglobinopathies, platelet & coagulation problems, and orphan hematopoietic system diseases are known to have higher mortality rates. Hematologic diseases in North America have increased is the past few years and hence it accelerated the demand for plasmapheresis machines in the market and the trend is expected to remain the same in near future.

Market Restraining Factors

• Apheresis-Related Complications

  In general, therapeutic apheresis is associated with a number of problems, the most prevalent of which are citrate-induced hypocalcemia and urticarial reactions to the protein-containing replacement fluid. When many units of fresh frozen plasma are utilized as the replacement fluid, the most serious consequences occur when an anaphylactic reaction occurs, and this is a significant restraint that can impede the growth of the market.

Key Market Opportunity

Emerging Markets Will Offer Profitable Prospects

Emerging markets, such as Mexico, offer both existing and new market participants great opportunities for total market expansion. This is owing to ongoing improvements in healthcare infrastructure, decreased regulatory barriers, growth in the target patient population, and increased healthcare spending. Regulatory policies in the Asia-Pacific region are more adaptive and business-friendly than in developed countries. Leading firms in the plasmapheresis machines market size have turned their focus to emerging areas due to growing competition in developed countries.

Regional Analysis

The United States, Canada, Mexico, and other powerful nations make up the American regional market. In terms of market share and income generated by essential enterprises in the region, it topped the global industry. This business is being propelled forward by the increased incidence of chronic disorders and technological improvements. The growing older population and the rising frequency of hematologic illnesses are driving the growth of the apheresis equipment market. Growing medical tourism in Mexico, on the other hand, is expected to boost the expansion of the North American apheresis equipment market in the coming years.

Furthermore, according to the US Census Bureau, the number of Americans aged 65 and older is expected to more than double from 46 million in 2016 to over 98 million by 2060, with the 65-and-older age group accounting for about 24% of the global population, up from 15%. As a result, the region's growing geriatric population is expected to boost the apheresis equipment market over the forecast period.

In light of a private company - Canadian Plasma Resources - planning to construct two plasma collection facilities in downtown Toronto that would reimburse donors, the topic of donating plasma for use in the creation of pharmaceutical products has received significant media attention.

Segmental Analysis

The North America plasmapheresis machines market size is segmented into type, application, end-user, and geographic segments.

Multicomponent Collection Systems (MCCS) is a form of the improved plasma collection system that catches various components of human blood during donation. It is commonly mixed with plasma and other components such as serum, RBCs, and leukocytes. Although some definitions determine multi-component collection as a technique that results in two different blood components, the vast majority of research publications written by scientists worldwide define multicomponent apheresis as a process that results in the collection of two or more identical or distinct blood components. These multicomponent collections typically use the same centrifugation procedures used for collecting each component individually under various circumstances.

Plasmapheresis is an extracorporeal therapy process because it involves the removal, treatment, return, and exchange of blood plasma/its components from and to the blood circulation. Extracorporeal refers to a medical procedure that is conducted outside of the body. The rising autoimmune disorders, such as thrombotic thrombocytopenic purpura, Goodpasture's syndrome, lupus, Guillain-Barre syndrome, myasthenia gravis, and other chronic illnesses, government reimbursement programs in developed countries, and rising demand for plasma-derived medicines are driving the growth of the extracorporeal therapy segment.

Due to the recent spike in the COVID-19 pandemic, the hospitals and clinics segment is likely to gain the most market share. This is primarily due to the increased frequency of therapeutic plasma exchange operations and increased plasma and blood component donations due to COVID-19 infection. Hospitals with in-house transfusion facilities are predicted to improve the most during the forecast period.

Impact of Covid-19

The automotive industry is critical to the economy's growth. However, during the second and third quarters of 2020, the COVID-19 outbreak impacted the whole automotive supply chain, affecting new car sales in FY 2020.

South America is most affected by COVID-19, with Brazil leading the way, followed by Ecuador, Chile, Peru, and Argentina. South America's government (SAM) has taken a number of steps to protect its citizens and stem the spread of COVID-19. South America is expected to have fewer export revenues as commodity prices fall and export volumes fall, particularly to China, Europe, and the United States, which are all significant trading partners. The manufacturing industry, especially automotive manufacturing, has been damaged by containment measures in various South American countries. Due to the pandemic, major automotive manufacturers have also temporarily halted manufacturing in the region as a cost-cutting move. Furthermore, the automobile disc brake industry has been significantly affected in 2020 due to a lack of raw materials and supply chain disruption.

The Automotive Brake System control module of a vehicle is meant to alert the driver with a warning light if the system fails. The module itself is rarely defective; instead, the sensors or the wiring to the sensors are frequently defective. The most typical cause of dysfunction is when the Automotive Brake System is contaminated with particles or metal shavings. There is no signal continuity when sensor wiring is destroyed. Brake fluid becomes contaminated in corrosive situations, and the hydraulic unit fails to function.

List of key players in North America Plasmapheresis Machines Market

1. Medica SPA
2. Terumo Corporation
3. Braun Melsungen AG
4. Fresenius Medical Care AG & Co. KGaA
5. Asahi Kasei Corporation
6. Haemonetics Corporation
7. HemaCare Corporation
8. KANEKA MEDIX CORPORATION
9. Baxter International Inc

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Recent Developments

• In 2021 – CSL Plasma Ltd. stated its intention not to extend its Supply Agreement with Haemonetics to use PCS2 plasma collection system equipment and acquire a disposable plasmapheresis kit in the United States after the present term expires in June 2022.