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Understand the influence of COVID-19 on the Nucleic Acid Isolation and Purification Market with our analysts monitoring the situation across the globe.

Market Overview

The nucleic acid isolation and purification market was valued at USD 2,400 million in 2019 and is expected to grow with a CAGR of 7.2% during the forecast period.

Critical care systems are designed to care for seriously ill patients, requiring 24-hour treatment and monitoring. The care systems include patient monitoring, respiratory and cardiac support, emergency resuscitation systems, and other life support equipment, which are extensively used in the field of life science research, genetic engineering, and forensics and molecular diagnostics.

Nucleic-Acid-Isolation-and-Purification-Market

Rising Prevalence of STDs to Increase the Demand for Nucleic Acid-Based Diagnostics

Increasing demand for pure nucleic acids in pharmaceutical and biotechnological firms and rising application of nucleic acid-based tests in diagnosis drive the market growth. Increasing government funding in R&D activities to develop technologically advanced solutions provide an impetus to the market growth. Nucleic acid-based diagnostics are widely used to treat umpteen medical conditions in laboratory settings.

The growing prevalence of cancer, infectious diseases, genetic disorders, and neglected tropical diseases is subsequently increasing the demand for DNA or RNA isolation for nucleic acid-based diagnostics. Nucleic acid has several diagnostic applications, which include STDs, congenital anomalies, and cancer. Almost all the STDs can be diagnosed using nucleic acid isolation and identification procedures, further driving the market growth. The World Health Organization (WHO) states that, globally, over a million sexually transmitted infections are acquired daily. Currently, about 500 million people suffer from herpes simplex virus (HSV), and 290 million women have human papillomavirus (HPV) infection.

Nucleic-Acid-Isolation-and-Purification-Market-Growth

Technological Advancements in Nucleic Acid-Based Diagnostics

The advent of new technologies in molecular diagnostics, such as expression analysis and genotyping, provides an impetus to the market growth. In the agriculture sector, the continuous advancement in science and technology has greatly revolutionized the production of genetically modified crops (GM).

Multiple traits introduced in GM crops using genetic engineering technologies include herbicide tolerance, drought tolerance, and crop resistance to insects. In line with this, the leading market players are actively working to develop automated nucleic acid insulation and purification solutions that allow for a faster, cleaner, and reliable process of nucleic acid extraction. In November 2019, Purigen Biosystems, Inc. launched the Ionic Purification System, which enables automated nucleic acid extraction from biological samples in an hour with higher yield and improved purity.

Nucleic Acid Isolation and Purification Market: Segmentation

Continuous Production of New DNA or RNA Insulation and Purification Kits by Prominent Players Drives the Segment Growth

The kits and reagents segment holds the highest market share on account of its widespread availability. The kits effectively isolate DNA or RNA from eukaryotic cells, bacteria, plasmid, virus, plants, seeds, and yeast in several downstream applications, including polymerase chain reactions. Continuous production of new DNA or RNA insulation and purification kits by prominent players drive the segment growth. In April 2019, Thermo Fisher introduced MagMax nucleic acid insulation kits-based on magnetic bead technology.

Rising Application of Viral DNA and Plasmid DNA Drive the DNA Isolation and Purification Segment Growth 

The division of DNA isolation and purification involves the isolation and purification of genomic, viral, plasmid, and other forms of DNA. The DNA isolation and purification segment is projected to witness the fastest growth on account of the rising application of viral DNA and plasmid DNA as gene therapy vectors and Nano biological tools. Similarly, rising use of plasmid DNA in gene therapy and vaccine development provides an impetus to the segment growth. 

Magnetic Bead-Based Segment to Hold the Largest Market Share  

The magnetic bead-based segment holds the largest market share as it uses high-capacity paramagnetic particles to isolate nucleic acids, providing higher yields and purity. Researchers are actively working to develop open-source protocols for magnetic bead-based methods, further driving the segment growth. For instance, the Bio-On-Magnetic-Beads (BOMB) is an open-source network consisting of magnetic bead process protocols that can assist a number of nucleic acid handling experiments.

Technological Advancements to Drive the Drug Discovery and Development Segment 

The drug discovery and development segment dominate the market on account of rapid technological advancement in the field of proteomics and genomics and development of advanced therapeutics in the healthcare industry, such as antisense therapy, gene therapy, and DNA vaccines. The newly developed techniques enable rapid detection of pathogenic activity at the DNA and RNA level, resulting in the detection of antimicrobial-resistant genes and characterization of strains using genotyping, further driving the segment growth.

Regional Overview

North-America-Lead-Nucleic-Acid-Isolation-and-Purification-Market

Increasing R&D Funding in Biotechnology and Healthcare Drive North America’s Nucleic Acid Isolation and Purification Market

North America leads the nucleic acid isolation and purification market as the region possesses rapid technological advancements, increasing R&D funding in biotechnology and healthcare, and growing use of nucleic acid isolation in food production, farming, and environmental testing. The region is also backed by the presence of food safety regulatory bodies, monitoring processed food products, such as the Food and Drug Administration (FDA) and the Food Safety and Inspection Service (FSIS).

As per the Centres for Disease Control and Prevention (CDC), in the U.S., hemophilia A affects one in every 5,000 male births, and approximately 400 babies are born with hemophilia A every year. The country is backed by the robust presence of prominent players, such as Thermo Fisher, Illumina, and Agilent Technologies, which are actively working to develop automatic systems for downstream applications, such as next-generation sequencing and PCR in real-time.

China to Hold the Largest Market Share in Asia-Pacific’s Nucleic Acid Isolation and Purification Market

Asia-Pacific is projected to witness the fastest growth in the nucleic acid isolation and purification market. China holds the largest share in the regional market on account of the rapid growth in the preparation of DNA and RNA libraries for next-generation sequencing. Additionally, a large number of life science laboratories in China are conducting experiments on the purification of nucleic acids, further boosting the regional market growth.

Key Players

  • QIAGEN
  • Illumina, Inc.
  • Danaher; F.
  • Hoffmann-La Roche Ltd.
  • Merck KGaA
  • Thermo Fisher Scientific, Inc.
  • Agilent Technologies
  • Bio-Rad Laboratories, Inc.
  • GE Healthcare
  • Promega Corporation
  • NorgenBiotek Corp

Recent Developments

  • In July 2019, Kerafast, Inc., a U.S.-based life sciences firm, signed an agreement with the Institute of Forest Genetics and Tree Breeding based in Coimbatore, India, to commercialize its ArborEasy DNA Isolation Kit and strengthen its product sales in the Indian market.
  • In May 2019, Thermo Fisher Scientific Inc. acquired a drug substance manufacturing site in Cork, Ireland, from GlaxoSmithKline plc. to expand its production capacity to meet customer demand

Nucleic Acid Isolation and Purification Market Segmentation

By Product

  • Kits
  • Reagents
  • Instruments

By Method

  • Column-Based Isolation and Purification
  • Reagent-Based Isolation and Purification
  • Magnetic Bead-Based Isolation and Purification

 By Type

  • Plasmid DNA Isolation and Purification
  • Total RNA Isolation and Purification
  • Genomic DNA Isolation and Purification
  • Messenger RNA Isolation and Purification
  • Micro RNA Isolation and Purification
  • Circulating Nucleic Acid Isolation and Purification
  • PCR Cleanup

By Application

  • Diagnostics
  • Drug Discovery and Development
  • Precision Medicine
  • Agriculture and Animal Research

By End-User

  • Research Centres and Academic and Government Institutes
  • Hospitals and Clinics
  • Pharmaceutical and Biotechnology Companies 

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Central and South America and the Caribbean
  • The Middle-East and Africa

Frequently Asked Questions (FAQs)

Increasing demand for pure nucleic acids in pharmaceutical and biotechnological firms and rising application of nucleic acid-based tests in diagnosis drive the market growth. Increasing government funding in R&D activities are the key factors expected to drive Nucleic Acid Isolation and Purification Market during forecast period.
In 2019 Global Nucleic Acid Isolation and Purification Market was valued at USD 2,400 million.
QIAGEN, Illumina, Inc., Danaher; F., Hoffmann-La Roche Ltd., Merck KGaA, Thermo Fisher Scientific, Inc., Agilent Technologies, Bio-Rad Laboratories, Inc., GE Healthcare are the top players in Nucleic Acid Isolation and Purification Market.
North America is expected to hold the highest market share in Nucleic Acid Isolation and Purification Market.
Magnetic Bead-Based Segment is expected to be leading segment in Nucleic Acid Isolation and Purification Market during the forecast period.
The nucleic acid isolation and purification market was valued at USD 2,400 million in 2019 and is expected to grow with a CAGR of 7.2% during the forecast period.
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