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NPPA India: Price Reductions for Non-scheduled Anti-cancer Drugs

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National Pharmaceutical Pricing Authority (NPPA), India’s drug price regulator’s latest Trade Margin Rationalisation (TMR) for 137 non-scheduled anti-cancer drugs took effect on 9 November 2026. As of 8 November, 85 companies had reported revised MRPs for 1,364 formulations covering 121 drugs; 679 brands reported cuts above 50%, with the largest reduction reaching 96.45%.

NPPA India: Price Reductions for Non-scheduled Anti-cancer Drugs

Selected Cancer Drugs Recording Price Cuts Under NPPA’s TMR Revision, November 2026

Drug Manufacturer/Brand Focus area Old MRP (₹) Revised MRP (₹) Approx. price cut

Bevacizumab 100 mg

Zydus Lifesciences– Bryxta

Lung, colon, ovarian & cervical cancer

25,995

3,318

87.2%

Bevacizumab 100 mg

Reliance Life Sciences– BevaciRel

Lung, colon, ovarian & cervical cancer

24,079

3,985

83.4%

Bevacizumab 100 mg

Hetero Healthcare– CIZUMAB

Lung, colon, ovarian & cervical cancer

15,658

3,103

80.2%

Denosumab 60 mg

Reliance Life Sciences– DenOsteoRel

Breast & prostate cancerBbone loss

24,955

6,240

75.0%

Pemetrexed 500 mg

Reliance Life Sciences– ReliTrexed

Lung cancer

9,977

1,113

88.8%

Pemetrexed 500 mg

Medicamen Biotech– PEMETOMED

Lung cancer

5,062

940

81.4%

Pertuzumab 420 mg

Lupin– LUPIHER 2

Breast cancer

83,520

37,358

55.3%

Azacitidine 100 mg

Dr. Reddy’s Laboratories–Azacytin

Blood cancers/Myelodysplastic syndromes

6,337

1,495

76.4%

Dasatinib 20 mg

Natco Pharma–Dasanat 20

Leukemia

2,812.50

1,085.93

61.4%

Denosumab 60 mg

RPG Life Sciences– Debrumab

Breast & prostate cancer/Bone loss

22,031.25

5,941

73.0%

Enzalutamide 40 mg

RPG Life Sciences– Enuta

Prostate cancer

6,578.20

2,232

66.1%

Erlotinib 150 mg

Neon Laboratories– ERLIB

Lung cancer

4,637.45

2,008

56.7%

Fludarabine 50 mg

Hetero Healthcare– FLUDANOX

Blood cancers

14,235

2,432

82.9%

Fulvestrant 50 mg

RPG Life Sciences– Fulbreca

Breast cancer

26,072.16

5,491

78.9%

Anastrozole 1 mg

RPG Life Sciences– ANARZOLE

Breast cancer

695.76

73

89.5%

Pegfilgrastim 6 mg

Hetero Healthcare– PEG FILTERO

Prevention of chemotherapy-induced neutropenia

9,093

1,631

82.1%

Abiraterone acetate 250 mg

Arvincare Pharma– ABIRONE

Prostate cancer

41,250

3,218.23

92.2%

The government itself highlighted examples such as Bryxta (bevacizumab) falling from ₹25,995 to ₹3,318, ReliTrexed (pemetrexed) from ₹9,977 to ₹1,113 and LUPIHER 2 (pertuzumab) from ₹83,520 to ₹37,358. Press Information Bureau The earlier NPPA release also lists anastrozole, azacitidine, dasatinib, denosumab, enzalutamide, erlotinib, fludarabine and fulvestrant among the revised brands.

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