Introduction
DNA polymerase is a group of enzymes that speeds up DNA synthesis during replication. A cell's DNA is duplicated during cell division. Nucleotides are added to the 3'OH group to digest the growing DNA strand. It is significant because it facilitates the transmission of genetic information from one generation to the next. The increasing demand for PCR and DNA sequencing technologies in research and clinical applications drives the market. The demand for DNA polymerases is anticipated to increase even further as genetic research develops and the demand for personalized medicine rises.
Market Dynamics
Increasing Incidence of Chronic Diseases Drives the Global Market
The DNA polymerase industry has a huge growth potential, given the prevalence of cancer, neurological disorders, genetic mutations, and the rise of chronic diseases. The WHO forecasts an increase in cancer-related fatalities of more than 70% over the following ten years. The market for DNA polymerase will expand as recombinant medications for treating chronic diseases become more prevalent.
Substantial Use of DNA Polymerase in the Biotechnology Industries Creates Tremendous Opportunities
Over the past ten years, the market has been growing quickly as a result of the increased use of DNA polymerase across numerous industries, including forensic science, biopharmaceuticals, research facilities, and diagnostic centers. Numerous biotechnological processes depend heavily on DNA polymerase, including the polymerase chain reaction (PCR), DNA cloning, DNA sequencing, single nucleotide polymorphism, whole genome amplification, and molecular diagnostics. Additionally, partnerships, the introduction of more recent DNA polymerase enzymes, and patent approval are the main techniques used by market participants.
Regional Analysis
North America dominates the market with a 47.28% share, which may be ascribed to the significant demand for biotechnology methods. Several large pharmaceutical and biotechnology firms have established research and development facilities. Commercial enterprises' widespread adoption of PCR, sequencing, and genetic engineering has increased the demand for DNA polymerases. For instance, Cepheid released the Xpert Xpress MVP in November of 2022. A single sample can be used in this multiplexed PCR assay to detect DNA from organisms linked to bacterial trichomoniasis, vaginosis, and vulvovaginal candidiasis. In addition, DNA polymerase is in higher demand in biotechnology labs for DNA replication and later extension due to the prevalence of chronic diseases like cancer, diabetes, and others.
Key Highlights
- The global DNA polymerase market size was valued at USD 0.141 billion in 2022. It is projected to reach USD 0.180 billion by 2031, growing at a CAGR of 2.50% during the forecast period (2023-2031).
- Based on the type, the DNA Polymerase market is bifurcated into Prokaryotic DNA Polymerase and Eukaryotic DNA Polymerase. The prokaryotic DNA polymerase segment owns the highest market share.
- Based on the application, the global DNA polymerase market is split into DNA cloning, SNP analysis, next-generation sequencing applications, and other applications. The DNA cloning segment is the highest contributor to the market and is expected to grow at a CAGR of 1.88% during the forecast period.
- Based on end-user, the global DNA polymerase market is categorized into pharmaceutical and biotechnology companies, academic and research institutes, diagnostic centers, and others. The diagnosis segment owns the highest market share and is expected to grow at a CAGR of 1.97% over the forecast period.
- North America dominates the market with a 47.28% share, which may be ascribed to the significant demand for biotechnology methods.
Competitive Players
Competitive Players
The global DNA Polymerases market key players are Novus Biologicals, Excell Bio, SYGNIS AG, New England Biolabs, Hoffmann-la Roche, Illumina Inc., Qiagen, Thermo Fisher Scientific, Agilent Technologies, Merck KGaA, and Others.
Recent Developments
Market News
- In April 2023, Agilent Technologies Inc. announced the launch of the Agilent Cancer Assay. This assay was developed in partnership with important cancer researchers for distinct somatic profiling for solid tumor types on a larger scale.
- In April 2023, Takara Bio Inc. announced that it had submitted a clinical trial application to Health Canada and had heard nothing to stop it from starting a trial for CD19 treatment. Once the operation is finished, the clinical trial will begin for patients who test CD19-positive.
- In September 2022, Oxidative damages were produced and repaired in "junk" DNA, according to research from the Healthy Life Span Institutes and the University of Sheffield's Neuroscience Department published. The discoveries open the door to the creation of cancer medications and cures for neurological diseases, including Alzheimer's and dementia.
Segmentation
Global DNA Polymerase Industry: Segmentation
By Type
- Prokaryotic DNA Polymerase
- Eukaryotic DNA Polymerase
- HiFi Polymerase
- phi29 Polymerase
By Application
- DNA Cloning
- SNP Analysis
- Next-Generation Sequencing Applications
- Other Applications
By End User
- Pharmaceutical and Biotechnology Companies
- Academic and Research Institutes
- Diagnostic Centers
- Others
By Regions
- North America
- Europe
- Asia-Pacific
- LAMEA