Global Intraoperative Radiation Therapy Market Revenue Grows at a CAGR of 8.17%

Introduction

Straits Research released its highly anticipated report, “Global Intraoperative Radiation Therapy Market Size & Outlook, 2026-2034”. According to the study, the market size is valued at USD 129.01 million in 2025 and is projected to expand to USD 260.67 million by 2034, registering a compound annual growth rate (CAGR) of 8.17%.

Market Dynamics

The global intraoperative radiation therapy (IORT) market is witnessing steady growth, primarily driven by the rising prevalence of various cancers and the growing demand for precise, targeted radiation therapies that minimize exposure to surrounding healthy tissues. Increasing incidences of breast, brain, gastrointestinal, and head and neck cancers worldwide are fueling the adoption of IORT, as this technology allows surgeons to deliver high-dose radiation directly to the tumor bed during surgery, reducing the need for prolonged post-operative radiation sessions. Additionally, advancements in mobile, compact, and image-guided IORT systems are enhancing procedural accuracy, workflow efficiency, and patient convenience, further supporting market expansion.

However, the market faces notable restraints due to the stringent regulatory and approval processes associated with medical radiation devices. IORT systems must undergo extensive clinical trials, safety evaluations, and compliance checks before market entry, which substantially increase development costs, delay commercialization, and limit the rapid adoption of innovative solutions. These regulatory complexities pose challenges for manufacturers seeking to introduce next-generation IORT technologies and may hinder the pace of market growth. On the other hand, a notable opportunity exists in the increasing integration of IORT in emerging and underserved regions, where hospitals and specialty clinics are investing in advanced cancer care infrastructure. The adoption of portable, cost-efficient, and mobile IORT devices enables broader accessibility in both urban and semi-urban centers.

Market Highlights

• Products & Services: The systems and accelerators segment held the highest revenue market share of 61.05% in 2025.
• Technology: The electron IORT segment dominated the market in 2025.
• Application: The breast cancer segment dominated the market in 2025 with a revenue share of 42.31%
• End User: The hospitals segment dominated the market in 2025.
• Regional Insights: North America dominated the market, accounting for 42.64% share in 2025, owing to the high concentration of leading oncology centers.

Competitive Players

1. BElekta AB
2. Carl Zeiss Meditec AG
3. Novacure, Inc.
4. Xoft, Inc.
5. Accuray Incorporated
6. Varian Medical Systems, Inc. (Siemens Healthineers)
7. Brainlab AG
8. IntraOp Medical, Inc.
9. Ion Beam Applications SA (IBA)
10. Mevion Medical Systems, Inc.
11. AAPM Technologies
12. RaySearch Laboratories AB
13. Innovative Radiation Solutions, Inc.
14. Theragenics Corporation
15. Sensus Healthcare, Inc.
16. IZI Medical Products
17. Best Theratronics Ltd.
18. ViewRay, Inc.
19. Others

Recent Developments

• September 2025: Accuray Incorporated launched the Accuray Stellar Solution in the U.S. market to address the evolving treatment of patients undergoing radiotherapy.

Segmentation

1. By Systems and Accelerators (2026-2034)
   1. Applicators & Afterloaders
   2. Treatment Planning Systems
   3. Accessories
   4. Services
2. By Technology (2026-2034)
   1. Electron IORT
   2. Intraoperative Brachytherapy
3. By Application (2026-2034)
   1. Breast Cancer
   2. Brain Tumor
   3. Gastrointestinal Cancer
   4. Head and Neck Cancer
   5. Colorectal Cancer
   6. Others
4. By End User (2026-2034)
   1. Hospitals
   2. Specialty Clinics
   3. Others
5. By Region (2026-2034)
   1. North America
   2. Europe
   3. Asia Pacific
   4. Latin America
   5. The Middle East and Africa