Market Dynamics
Global Preparative and Process Chromatography Market Drivers
Growing Prevalence of Diabetes across the Globe
According to the International Diabetes Federation, in 2019, approximately 463 million adults are living with diabetes, and by 2045 the number will rise to 700 million. There is a rising demand for insulin as the amount of insulin needed to effectively treat type 2 diabetes would rise by more than 20 percent over the next 12 years. More than half of the population in China, India, and the U.S. within the age group of 20 to 79, are living with type 2 diabetes. These numbers are expected to soar up to more than 500 million by 2030 in these countries.
The overall cost of treatment for chronic diabetes depends on the cost of insulin. The financial burden for the treatment of diabetes is a challenge for all the healthcare systems around the world, even though insulin is a relatively low-priced drug, however, the chronic nature of diabetes leads to elevated cost for insulin treatment, and together with an increasing number of patients around the world creating a challenge to deal. Thus, a price reduction of insulin is needed to improve its availability especially in lower to lower-middle-income countries. Therefore, optimization of the purification chromatography is required to obtain a secure production of high purity insulin with maximum yield.
Therefore, the mounting diabetic population leading to rising demand for insulin is increasing the gravity of the situation for developing better and effective methods of extraction and purification chromatography. Thus, giving rise to the demand for chromatography and driving the market growth.
Increasing Consumer Awareness about the Health Benefits of Omega-3
Omega-3 fatty acids are a group of polyunsaturated fatty acids that are required for certain vital functions and benefits in the human body, but the body cannot produce these fatty acids on its own, thus are required to source from outside in the form of a supplement. These Omega-3 fatty acids such as Alpha-linolenic acid (ALA) is important for the eye, nerve, and membrane development, whereas Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) are significant for the production of prostaglandins, that help to regulate blood pressure, inflammation, neurological functions, hormones production, etc. in the human body.
A daily intake of 250 mg of Omega-3 per adult gives optimal protection against diseases such as coronary heart disease, also for children, 150 mg per day is enough for optimal brain development. Fish are the natural food source of omega-3 fatty acids. As people are becoming more health-conscious, there is an increased demand for supplements.
With the increased focus, research, and knowledge on the beneficial properties of these fatty acids, demand for omega-3 supplements has skyrocketed. Thus, extraction and purification chromatography gives the maximum yield for Omega-3 to meet the requirement. Therefore, driving market growth.
Rise in Geriatric Population Boosting Market Growth
The aging population is projected to nearly double from 52 million in 2018 to 95 million by 2060. The 65-and-older age group's share of the total population will rise from 16% to 23% in the U.S. The elderly population is more prone to diabetes, cardiovascular diseases, etc. Resulting in an increased economic pressure on the public finances, which goes towards the health management of the aging population, placing stress on the redistribution of income from the young to the retired.
Japan is the biggest example of facing the problem of the aging population for putting forward secular stagnation in a country. Chromatography helps in the process of extraction and purification of important biopharmaceutical products with maximum yield such as insulin, supplements, monoclonal antibodies, etc., reducing the prices of these products and thus leading to relaxing the stress on the public incomes. Therefore, it is contributing to the growth of the market.
Global Preparative and Process Chromatography Market Opportunities
Rising Awareness and Demand for Monoclonal Antibodies across the Globe
Monoclonal antibodies (mAb) are laboratory-produced molecules, designed to bind specifically with the cancer cells and engineered to serve as substitute antibodies that can restore or enhance the immune system's attack on cancer cells. Making it easier to identify a cancerous cell from healthy cells, which then can be treated or removed. According to WHO, cancer is the second leading cause of death globally and is responsible for an estimated 9.6 million deaths in 2018. Globally, about 1 in 6 deaths is due to cancer.
Size exclusion chromatography (SEC) is an important process used in the separation and purification of mAb, thus, leading to the increased demand for preparative and process chromatography, and boosting the growth of the market.
Regional Analysis
North America to Dominate the Market during the Forecast Period
North America dominates the preparative and process chromatography market as the region is backed by a well-established healthcare system, high disposable income, high penetration, and adoption rate for biopharmaceutical products, increase in awareness for health-conscious, therefore, resulting in the increased demand for preparative and process chromatography. Moreover, the rising geriatric population leading to the surging prevalence of target diseases such as diabetes, cardiovascular diseases, etc. in the region is further anticipated to propel market growth.
According, the U.S. Department of Health & Human Services, in 2019, 34.2 million Americans have diabetes, and the number is growing. Besides, the local presence of key players such as Johnson & Johnson, Merck & Co., etc. is also one of the indicators that portray its current huge market potential.
Furthermore, lifestyle changes such as increased alcohol and tobacco consumption, absence of physical activities, inactive work life, and dietary habits which include high intake of saturated fats and sugars are observed among the adult population. These factors increase the risk of diabetes, cardiovascular and other diseases. Therefore, leading to the rising burden of target diseases is expected to boost the market in the forthcoming years. Thus, these factors contribute to accelerated regional market growth.
Impact of covid-19
With the rapid spread of the COVID-19 virus across the globe, the need for essential medical devices/equipment is also increasing. The COVID-19 infection is measured based on oxygen levels in the bloodstream and is characterized as normal to severe and even life-threatening. So, the need for oxygen support devices like ventilators, oxygen concentrators, etc., is rising day by day with the increasing number of cases of COVID-19 patients across the globe. Breathlessness is a major issue with the patients suffering from COVID-19, thus requiring an oxygen concentrator device.
As per the American Journal of Tropical Medicine and Hygiene (ASTMH), the symptoms start arising within 7-10 days of illness. The current treatment for severe COVID-19 depends majorly on providing the best possible oxygen supportive care. Patients infected with the COVID-19 virus may suffer from mild to severe symptoms.
With hospitals being overcrowded and the lack of ventilators' availability in underprivileged settings is a challenge, oxygen concentrators are proving to be helpful in such situations. As most cases are patients with mild symptoms who don't require ventilator support, breathing therapy by oxygen concentrator helps stabilize the health of the patient. Thus, it is contributing to the medical oxygen concentrators market growth.
