Gelatin Polypeptide Plasma Expanders Market Size, Share & Trends Analysis Report By Type: (Polygeline, Succinylated Gelatin), By Sources of Gelatin: (Porcine, Bovine), By Application: (Preoperative Prevention, Extracorporeal Circulation, Dialysis) and By Region (North America, Europe, APAC, Middle East and Africa, LATAM) Forecasts, 2026-2034

Last Updated: September 02, 2026 | Author: Debashree Bora | Format:

Market Overview

The global gelatin polypeptide plasma expanders market size was valued at USD 2.24 billion in 2025 and is projected to grow from USD 2.31 billion in 2026 to USD 3.00 billion by 2034, registering a CAGR of 3.3% during the forecast period from 2026 to 2034. North America dominated the gelatin polypeptide plasma expanders market with a market share of 38.45% in 2025.

Plasma expander, also known as plasma compatibilizer, is a plasma substitute. The global market for gelatin polypeptide plasma volume enhancers is highly concentrated. Plasma expanders are currently available in two types: colloid and crystalloid. It can be used as an alternative to dextran, albumin, and other colloidal expanders.

Volume expanders are extensively used in orthopedic, hepatic, and vascular surgeries daily. It is also used in an emergency or critical situation involving blood loss. According to CDC, in 2018, 35 million injury-related emergency care patients were admitted in the US. Thus, increasing the demand for plasma expanders and driving the market growth.

Gelatin Polypeptide Plasma Expanders Market Size

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Segmental Analysis

Kinds of Plasma Expanders

The market is divided into three segments based on application: perioperative, extracorporeal circulation, and dialysis. Perioperative had the largest market share, amounting to USD 134.6 million in 2018 due to a high number of surgeries and subsequent blood loss, mandating the use of plasma expanders to maintain plasma volume. Porcine gelatin, essentially made from pigskin, is the leading source of gelatin. It is preferred as it is cheaper and hence produces a huge market revenue.

Gelatin Polypeptide Plasma Expanders Market Size By Segments

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Gelatin Polypeptide Plasma Expanders Market Share By Segments

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Regional Analysis

North America Exhibits Humongous Demand

North America dominates the market. An intravenous volume expander is used in treating blood diseases, blood loss, hypovolemia, pancreatitis, and trauma. The treatment aids people injured in a severe accident. The number of road accidents is increasing at an alarming rate in North America, and many of these incidents are caused by drunk driving. These accidents result in injuries, life-long impairment, or death, depending on their severity. In the United States, 12 million vehicles were involved in accidents in 2018.

Over 4.4 billion people live in Asia-Pacific. The region provides reasonably decent healthcare at a low cost and bears the brunt of the global disease burden. Cancer, heart diseases, diabetes, and COPD affect Japan, Australia, and South Korea. Many countries in Asia-Pacific have boosted their healthcare spending to provide better healthcare services.

North America Gelatin Polypeptide Plasma Expanders Market Revenue Share 2025

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List of Key and Emerging Players in Gelatin Polypeptide Plasma Expanders Market

B. Braun Medical Ltd.

Abbott

Piramal Pharma

Fresenius Kabi AG

Sanofi

Serumwerk Bernburg AG

Beacon Pharmaceuticals Ltd.

Key Industry Developments

June 2026

Fresenius Kabi expanded its plasma volume replacement and infusion therapy portfolio with advanced solutions for critical care applications. The company focused on improving fluid management, patient safety, and hospital care capabilities through innovative plasma expander products.

March 2026

B. Braun expanded its infusion therapy portfolio with new volume replacement and clinical nutrition solutions. The developments support healthcare providers with improved fluid resuscitation options and enhanced patient management in surgical and emergency care settings.

January 2026

Vifor Pharma expanded its hospital care solutions portfolio with advancements in supportive therapies for critical care and perioperative applications. The company focused on improving treatment options for patients requiring specialized fluid management.

October 2025

Medtronic expanded its patient care solutions portfolio with advancements in hospital-based therapies and fluid management technologies. The initiatives support improved clinical workflows and treatment efficiency in critical care environments.

Report Scope

Segmentation

By Type: 2

Polygeline
Succinylated Gelatin

By Sources of Gelatin: 2

Porcine
Bovine

By Application: 3

Preoperative Prevention
Extracorporeal Circulation
Dialysis

Geographies Covered

North America 2

U.S.
Canada

Europe 8

U.K.
Germany
France
Spain
Italy
Russia
Nordic
Benelux

APAC 7

China
Korea
Japan
India
Australia
Taiwan
South East Asia

Middle East and Africa 6

UAE
Turkey
Saudi Arabia
South Africa
Egypt
Nigeria

LATAM 5

Brazil
Mexico
Argentina
Chile
Colombia

Competitive Coverage B. Braun Medical Ltd. · Abbott · Piramal Pharma · Fresenius Kabi AG · Sanofi

Research Deliverables Revenue Forecast, Competitive Landscape, Growth Factors, Environment & Regulatory Landscape and Trends

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Frequently Asked Questions (FAQs)

The gelatin polypeptide plasma expanders market size is valued at USD 2.31 Billion in 2026 and is projected to reach USD 3.00 Billion by 2034, at a CAGR of 3.3% during the forecast period 2026-2034.

North America dominated the market with a share of 38.45% in 2025.

The leading players in this market are B. Braun Medical Ltd., Abbott, Piramal Pharma, Fresenius Kabi AG, Sanofi.

The gelatin polypeptide plasma expanders market is projected to grow at a CAGR of 3.3% during the forecast period of 2026 2034.

About the Author

Debashree Bora

Healthcare Lead

Debashree Bora is a strategic healthcare research professional with nearly eight years of hands on experience in market intelligence, encompassing primary research, secondary research, market estimation, and consulting engagements. She specializes in pharmaceutical, biotechnology, medical devices, healthcare services, clinical trials, and healthcare outsourcing sectors, providing actionable insights on evolving industry trends, regulatory landscapes, and competitive dynamics.
Debashree’s research helps global clients evaluate market potential, identify growth opportunities, strengthen commercial strategies, and make informed business decisions.