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Europe Organ-On-Chip Market Size, Share & Trends Analysis Report By Organ Type (Heart on chip, Human on chip, Intestine on chip, Kidney on chip, Liver on chip, Lung on chip), By Applications (Drug Discovery, Toxicology Research, Physiological Model Development), By End-User (Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Others) and By Country(U.K., Germany, France, Italy, Russia, Nordic, Benelux, Rest of Europe) Forecasts, 2024-2032

Report Code: SRBI56413DR
Last Updated : Aug 26, 2024
Author : Straits Research
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Europe Organ-On-Chip Market Size and Trends

The European organ-on-chip market size was valued at USD 94.51 million in 2023. It is estimated to reach USD 1,103.66 million by 2032, growing at a CAGR of 31.4% during the forecast period (2024–2032). In recent years, there has been a rise in regulatory support for the development of alternative experimentation methods for animal testing, which is anticipated to drive the European organ-on-chip market. Moreover, there has been a rise in research funding and collaborative efforts taken by the major stakeholders in the market to advance organ-on-chip technology for its better efficiency, thereby creating opportunities for regional market expansion.

Europe Organ-On-Chip Market

Europe Organ-On-Chip Market Growth Factors

Increasing Regulatory Support for Alternative Testing Methods

The European Organ-On-Chip (OOC) market is bolstered by growing regulatory support for alternative testing methods to animal experimentation. European regulatory bodies, including the European Medicines Agency (EMA) and the European Centre for the Validation of Alternative Methods (ECVAM), are advocating for the adoption of more ethical, human-relevant testing approaches. Organ-on-chip technology aligns with the European Union's directive to reduce animal testing, particularly in drug development and toxicology assessments.

This regulatory encouragement is accelerating the integration of OOC devices into preclinical testing frameworks. Additionally, the EU's stringent regulations on animal welfare, coupled with its emphasis on scientific advancements, are driving pharmaceutical and biotechnology companies to adopt Organ-On-Chip models. This regulatory push is not only fostering innovation but also ensuring that Europe remains at the forefront of developing humane and effective testing alternatives.

Europe Organ-On-Chip Market Restraint

High Cost and Technical Challenges

Despite the promising potential of Organ-On-Chip technology, its adoption in Europe faces significant restraints, primarily due to high costs and technical challenges. The development and production of OOC devices involve advanced microfabrication techniques, specialized materials, and complex integration of biological components, leading to substantial costs. Thus, the high cost of manufacturing and maintaining OOC devices limits their widespread adoption, particularly among small and medium-sized enterprises (SMEs) in the pharmaceutical and biotechnology sectors.

Additionally, the technology is still in its early stages, with technical challenges such as ensuring the long-term viability of cells within the chips, replicating the complexity of human organs, and achieving standardization across different OOC models. The lack of standardized protocols and regulatory frameworks for OOC technology further complicates its commercialization. These challenges, coupled with the need for significant upfront investment, are restraining the growth of the European OOC market, especially among companies with limited resources.

Europe Organ-On-Chip Market Opportunities

Expansion of Research Funding and Collaboration

The European Organ-On-Chip market presents substantial opportunities, particularly through the expansion of research funding and collaborative initiatives. The European Union (EU) has been actively promoting innovation in biomedical research, with a focus on developing alternative methods to traditional animal testing. The Horizon Europe program, which has allocated €95.5 billion for research and innovation from 2021 to 2027, includes significant funding for Organ-On-Chip technology.

This financial support is encouraging the development and commercialization of OOC devices, enabling researchers and companies to overcome the existing technical and cost-related challenges. Moreover, increasing collaborations between academic institutions, research organizations, and industry players are driving the advancement of OOC technology. For instance, the Human Organ and Disease Model Technologies (ORGANs) project, funded by the EU, is a collaborative effort to develop standardized OOC platforms for various applications. These initiatives are fostering innovation, accelerating the development of more robust and accessible OOC systems, and opening new avenues for market growth in Europe.

Study Period 2020-2032 CAGR 31.4%
Historical Period 2020-2022 Forecast Period 2024-2032
Base Year 2023 Base Year Market Size USD 94.51 million
Forecast Year 2032 Forecast Year Market Size USD 1,103.66 million
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Europe Organ-On-Chip Market Regional Analysis

The European Organ-On-Chip market is led by Germany, the UK, France, and the Netherlands and is driven by strong pharmaceutical sectors, government funding, and research infrastructure. Germany and the UK dominate, with significant investments in OOC technology, while France and the Netherlands are emerging due to their innovation in microfluidics and biomedical research. Additionally, there has been a rise in the initiatives by researchers and academic institutes to advance organ-on-chip technology.

For instance, in April 2024, the Middle Eastern Technical University Electromechanical Systems (ODTÜ MEMS) Center researchers are currently undertaking a groundbreaking effort to create a chip that has the potential to transform pharmaceutical research by substituting animal testing. The "Strategic Partnership Focused on Organ-on-Chip Systems (OrChESTRA)" initiative, funded by the European Union's Horizon Europe program, seeks to position the MEMS Center as a prominent player in the field of organ-on-chip technology within the region.

Moreover, the market players in this region are involved in strategic initiatives to enhance their market share. For instance, in January 2024, Cambridge-based biotech companies CN Bio and Altis Biosystems collaborated to integrate Altis' RepliGut Planar-Jejunum model, an in vitro 'organ-on-a-chip' system, with CN Bio's PhysioMimix liver on a chip. The PhysioMimix liver-on-a-chip developed by CN Bio is a microphysiological system (MPS) designed to replicate the functioning of the human liver. The technologies are anticipated to eliminate the necessity for preclinical animal experiments and reduce drug development expenses. Consequently, all these factors are expected to augment the European organ-on-chip market growth.

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Europe Organ-On-Chip Market Segmentation Analysis

The liver-on-chip segment dominated the organ type segment and is expected to grow at a CAGR of 30.8% in the European organ-on-chip market. The Liver-On-Chip segment is expanding in Europe due to the liver's critical role in drug metabolism and toxicity testing. These chips provide a more accurate model for assessing liver function and drug-induced hepatotoxicity, which is crucial for predicting human responses and improving drug safety, driving their adoption in pharmaceutical and biotechnology research.

The toxicology research segment is estimated to own the application segment and is anticipated to expand at a CAGR of 31.0% in the European organ-on-chip market. The toxicology research segment is expanding in the European Organ-On-Chip market as OOC devices offer more precise and ethical alternatives to animal testing. These chips replicate human organ responses, enabling accurate assessment of drug toxicity and safety, thus aligning with stringent European regulatory requirements and reducing the risk of adverse drug reactions.

The pharmaceutical and biotechnology companies segment held the largest market share and is estimated to develop at a CAGR of 30.7% over the forecast period. The pharmaceutical and biotechnology companies' end-user segment in the European Organ-On-Chip market is growing due to the increasing demand for advanced, human-relevant models in drug discovery and development. These companies are investing in Organ-On-Chip technology to enhance drug testing accuracy, reduce clinical trial failures, and accelerate the development of personalized medicines.

Market Size By Organ Type

Market Size By Organ Type
  • Heart on chip
  • Human on chip
  • Intestine on chip
  • Kidney on chip
  • Liver on chip
  • Lung on chip


  • List of key players in Europe Organ-On-Chip Market

    1. AxoSim Inc.
    2. BiomimX SRL
    3. CN Bio
    4. Emulate Inc.
    5. Hurel Corporation
    6. InSphero AG
    7. MIMETAS BV Nortis Inc.
    8. Tara Biosystems Inc.
    9. TissUse GmbH
    10. Others
    Europe Organ-On-Chip Market Share of Key Players

    Europe Organ-On-Chip Market Segmentations

    By Organ Type (2020-2032)

    • Heart on chip
    • Human on chip
    • Intestine on chip
    • Kidney on chip
    • Liver on chip
    • Lung on chip

    By Applications (2020-2032)

    • Drug Discovery
    • Toxicology Research
    • Physiological Model Development

    By End-User (2020-2032)

    • Pharmaceutical and Biotechnology Companies
    • Academic and Research Institutes
    • Others

    Frequently Asked Questions (FAQs)

    How big is the European Organ-On-Chip Market?
    The European organ-on-chip market size is estimated to reach USD 1,103.66 million by 2032, growing at a CAGR of 31.4% during the forecast period (2024–2032).
    The key European organ-on-chip market players are AxoSim Inc., BiomimX SRL, CN Bio, Emulate Inc., Hurel Corporation, InSphero AG, MIMETAS BV Nortis Inc., Tara Biosystems Inc., TissUse GmbH, and others.
    The European organ-on-chip market is segmented by organ type, application, and end-user.


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